Structure of protein geranylgeranyltransferase-I from the human pathogen Candida albicans complexed with a lipid substrate

Journal of Biological Chemistry

Volumn 283, Issue 46, 2008, Pages 31933-31940

  Hast, Michael A ^a   Beese, Lorena S ^a,b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b DCMB Group   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; MAMMALS; PATHOGENS; PROTEINS; SIGNAL TRANSDUCTION; SULFUR;

ACTIVE SITES; ALBICANS; ANTICANCER THERAPEUTICS; ANTIFUNGAL ACTIVITIES; BINDING POCKETS; C TERMINUSES; CANDIDA ALBICANS; CAUSATIVE AGENTS; CELLULAR PROTEINS; CRITICAL AREAS; CYSTEINE RESIDUES; FUNGAL INFECTIONS; GERANYLGERANYL TRANSFERASES; GTPASES; HIGH RESOLUTIONS; HOMOLOGOUS PROTEINS; HUMAN PATHOGENS; INFECTIOUS DISEASES; ISOPRENOID; ISOPRENOID LIPIDS; MAMMALIAN PROTEINS; ONCOGENESIS; PRENYLTRANSFERASE; PROTEIN PRENYLATION;

CRYSTAL STRUCTURE;

DIMETHYLALLYLTRANSFERASE; GERANYLGERANYL PYROPHOSPHATE; GERANYLGERANYLTRANSFERASE 1; ISOPRENOID; LIPID; TRANSFERASE; UNCLASSIFIED DRUG;

ARTICLE; CANDIDA ALBICANS; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

ALKYL AND ARYL TRANSFERASES; BINDING SITES; CANDIDA ALBICANS; CRYSTALLOGRAPHY, X-RAY; HUMANS; LIPID METABOLISM; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN PRENYLATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; SUBSTRATE SPECIFICITY;

CANDIDA ALBICANS; MAMMALIA; PROTOZOA;

EID: 57649116081     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M805330200     Document Type: Article

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