15N-1H HSQC NMR evidence for distinct specificity of two active sites in Escherichia coli glyoxalase I

Biochemistry

Volumn 47, Issue 50, 2008, Pages 13232-13241

  Su, Zhengding ^a   Sukdeo, Nicole ^a   Honek, John F ^a  

^a UNIVERSITY OF WATERLOO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ESCHERICHIA COLI; IONS; METAL IONS; NUCLEAR MAGNETIC RESONANCE; PLANNING; STRATEGIC PLANNING; TITRATION; VOLUMETRIC ANALYSIS;

ACTIVE SITES; E. COLI; ENZYME SYSTEMS; FUNCTION RELATIONSHIPS; GLUTATHIONE; GLYOXALASE; HOMODIMERIC PROTEINS; HSQC NMR; ISOTHERMAL TITRATIONS; METALLATION; NEW STRATEGIES; OLIGOMERIC PROTEINS; POTENT INHIBITORS; SMALL MOLECULES; SPECTROSCOPIC EVIDENCES; X-RAY STRUCTURES;

NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ENZYME INHIBITOR; LACTOYLGLUTATHIONE LYASE; NICKEL; ESCHERICHIA COLI PROTEIN; NITROGEN; PROTON;

ARTICLE; ENZYME SPECIFICITY; ESCHERICHIA COLI; HETERONUCLEAR SINGLE QUANTUM COHERENCE; METALLATION; NITROGEN NUCLEAR MAGNETIC RESONANCE; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; AMINO ACID SEQUENCE; BINDING SITE; CHEMISTRY; COMPARATIVE STUDY; GENETICS; METABOLISM; METHODOLOGY; MOLECULAR GENETICS; NUCLEAR MAGNETIC RESONANCE; PROTEIN SECONDARY STRUCTURE;

ESCHERICHIA COLI;

AMINO ACID SEQUENCE; BINDING SITES; ESCHERICHIA COLI PROTEINS; LACTOYLGLUTATHIONE LYASE; MOLECULAR SEQUENCE DATA; NITROGEN ISOTOPES; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN STRUCTURE, SECONDARY; PROTONS; SUBSTRATE SPECIFICITY;

EID: 57649116071     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi8013278     Document Type: Article

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