HPV in situ hybridization signal patterns as a marker for cervical intraepithelial neoplasia progression

Gynecologic Oncology

Volumn 112, Issue 1, 2009, Pages 114-118

  De Marchi Triglia, Renata ^a   Metze, Konradin ^a   Zeferino, Luiz Carlos ^a   Lucci De Angelo Andrade, Liliana A ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Cervical intraepithelial neoplasia; Disease progression; HPV; In situ hybridization; Integration

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; BASAL CELL; CANCER GROWTH; CELL COUNT; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE MARKER; EPITHELIUM; FEMALE; FISHER EXACT TEST; FOLLOW UP; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RANK SUM TEST; UTERINE CERVIX BIOPSY; UTERINE CERVIX CARCINOMA IN SITU; WART VIRUS;

ADOLESCENT; ADULT; AGED; BIOPSY; CELL TRANSFORMATION, VIRAL; CERVICAL INTRAEPITHELIAL NEOPLASIA; DISEASE PROGRESSION; DNA, VIRAL; FEMALE; HUMANS; IN SITU HYBRIDIZATION; MIDDLE AGED; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS INFECTIONS; RETROSPECTIVE STUDIES; UTERINE CERVICAL NEOPLASMS; VIRUS INTEGRATION; YOUNG ADULT;

EID: 57649110514     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2008.09.047     Document Type: Article

References (25)

1. Pett M., and Coleman N. Integration of high-risk human papillomavirus: a key event in cervical carcinogenesis?. J. Pathol. 212 (2007) 356-367
2. Hopman A.H.N., Kamps M.A., Smedts F., et al. HPV in situ hybridization: impact of different protocols on the detection of integrated HPV. Int. J. Cancer 115 (2005) 419-428
3. Evans M.F., Mount S.L., Beatty B.G., and Cooper K. Biotinyl-tyramide-based in situ hybridization signal patterns distinguish human papillomavirus type and grade of cervical intraepithelial neoplasia. Mod. Pathol. 15 12 (2002) 1339-1347
4. Song S.H., Lee J.K., Oh M.J., Hur J.Y., Park Y.K., and Saw H.S. Risk factors for the progression or persistence of untreated mild displasia of uterine cervix. Int. J. Gynecol. Cancer 16 (2006) 1608-1613
5. Vinokurova S., Wentzensen N., Kraus I., et al. Type-dependent integration frequency of human papillomavirus genomes in cervical lesions. Cancer Res. 68 1 (2008) 307-313
6. INK4a immunoexpression and high-risk in situ hybridization signal types. Am. J. Clin. Pathol. 128 (2007) 208-217
7. Kalof A.N., Evans M.F., Simmons-Arnold L., Beatty B.G., and Cooper K. p16 immunoexpression and HPV in situ hybridization signal patterns. Potential markers of high-grade cervical intraepithelial neoplasia. Am. J. Surg. Pathol. 29 (2005) 674-679
8. Bryan J.T., Taddeo F., Skulsky D.M., et al. Detection of specific human papillomavirus types in paraffin-embedded sections of cervical carcinomas. J. Med. Virol. 78 (2006) 117-124
9. Herrington C.S. Demystified...in situ hybridization. J. Clin. Pathol.: Mol. Pathol. 51 (1998) 8-13
10. Biedermann K., Dandachi N., Trattner M., et al. Comparison of real-time PCR signal-amplified in situ hybridization and conventional PCR for the detection and quantification of human papillomavirus in archival cervical cancer tissue. J. Clin. Microbiol. 42 8 (2004) 3758-3765
11. Cooper K., Herrington C.S., Stickland J.E., Evans M.F., and McGee J.O.D. Episomal and integrated human papillomavirus in cervical neoplasia shown by non-isotopic in situ hybridization. J. Clin. Pathol. 44 (1991) 990-996
12. Plummer T.B., Sperry A.C., Xu H.S., and Lloyd R.V. In situ hybridization detection of low copy nucleic acid sequences using catalyzed reporter deposition and its usefulness in clinical human papillomavirus typing. Diagn. Mol. Pathol. 7 (1998) 76-84
13. Guo M., Gong Y., Deavers M., Silva E.G., et al. Evaluation of a commercialized in situ hybridization assay for detecting HPV DNA in tissue specimens from patients with cervical intraepithelial neoplasia and cervical carcinoma. J. Clin. Microbiol. 46 (2008) 274-280
14. Kalof A.N., and Cooper K. Our approach to squamous intraepithelial lesions of the uterine cervix. J. Clin. Pathol. 60 (2007) 449-455
15. Gallo G., Bibbo M., Bagella L., et al. Study of viral integration of HPV 16 in young patients with LSIL. J. Clin. Pathol. 56 (2003) 532-536
16. Lizard G., Démares-Poulet M.-J., Roignot P., and Gambert P. In situ hybridization detection of single-copy human papillomavirus on isolated cells, using a catalyzed signal amplification system: GenPoint. Diagn. Cytopathol. 24 2 (2001) 112-115
17. Sano T., Hikino T., Niwa Y., et al. In situ hybridization with biotinylated tyramide amplification: detection of human papillomavirus DNA in cervical neoplastic lesions. Mod. Pathol. 11 1 (1998) 19-23
18. Dabic M.M., Hlupic L., Babic D., Jukic S., and Seiwerth S. Comparison of polymerase chain reaction signal amplification in situ hybridization methods for human papillomavirus detection in paraffin-embedded cervical preneoplastic and neoplastic lesions. Arch. Med. Res. 35 (2004) 511-516
19. Bernal M., Burillo I., Mayordomo J.I., Moros M., Benito R., and Gil J. Human papillomavirus (HPV) infection and intraepithelial neoplasia and invasive cancer of the uterine cervix: a case-control study in Zaragoza, Spain. Infect. Agent Cancer 3 (2008) 8-11
20. Evans M.F., and Cooper K. Human papillomavirus integration: detection by in situ hybridization and potential clinical implication. J. Pathol. 202 (2004) 1-4
21. Evans M.F., Aliesky H.A., and Cooper K. Optimization of biotinyl-tyramide-based in situ hybridization for sensitive background-free applications on formalin-fixed, paraffin-embedded tissue specimens. BMC Clin. Pathol. 3 1 (2003) 2
22. Evans M.F., Adamson C.S.C., and Cooper K. Evidence of HPV16 integration in low- and high-grade cervical lesions that regress demonstrated by multiple displacement amplification and Southern blot hybridization. J. Clin. Pathol. 61 (2008) 541-543
23. Cooper K., Evans M., and Mount S. Biology and evolution of cervical squamous intraepithelial lesions: a hypothesis with diagnostic prognostic implications. Adv. Anat. Pathol. 10 (2003) 200-203
24. Kulmala S.-M.A., Syrjanen S.M., Gyllenten U.B., et al. Early integration of high copy HPV16 detectable in women with normal and low grade cervical cytology and histology. J. Clin. Pathol. 59 (2006) 513-517
25. Schiller C.L., Nickolov A.G., Kaul K.L., et al. High-risk human papillomavirus detection: a split-sample comparison of hybrid capture and chromogenic in situ hybridization. Am. J. Clin. Pathol. 121 (2004) 537-545