Anorectal Function After Three- Versus Two-Dimensional Radiation Therapy for Carcinoma of the Prostate

International Journal of Radiation Oncology Biology Physics

Volumn 73, Issue 1, 2009, Pages 46-52

  Yeoh, Eric K ^a   Holloway, Richard H ^a   Fraser, Robert J ^b   Botten, Rochelle ^a   Di Matteo, Addolorata ^a   Moore, James W ^a   Schoeman, Mark N ^a   Bartholomeusz, Dylan L ^a  

^a ROYAL ADELAIDE HOSPITAL   (Australia)

^b REPATRIATION GENERAL HOSPITAL   (Australia)

Author keywords

3D CRT; Anorectal function; Manometry; Prostate cancer; Radiotherapy

Indexed keywords

PROBABILITY DENSITY FUNCTION; RADIATION EFFECTS; RADIOTHERAPY; TWO DIMENSIONAL;

3D CRT; ANORECTAL FUNCTION; BASE-LINES; EXTERNAL-; FECAL INCONTINENCES; MANOMETRY; PATHO PHYSIOLOGIES; PROGNOSTIC SIGNIFICANCES; PROSTATE CANCER; PROSTATE CARCINOMATA; RADIATION THERAPIES; SENSORY FUNCTIONS; TREATMENT GROUPS; TREATMENT TECHNIQUES;

THREE DIMENSIONAL;

ADULT; AGED; ANORECTAL DISEASE; ANORECTAL PRESSURE; ANUS SPHINCTER; ARTICLE; BEAM THERAPY; CANCER LOCALIZATION; CANCER RADIOTHERAPY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DEFECATION; DEFECATION URGENCY; FECES INCONTINENCE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; PROSTATE CARCINOMA; RADIATION DOSE FRACTIONATION; RANDOMIZED CONTROLLED TRIAL; RECTUM HEMORRHAGE; THREE DIMENSIONAL RADIATION THERAPY; TREATMENT OUTCOME; TWO DIMENSIONAL RADIATION THERAPY;

AGED; AGED, 80 AND OVER; ANUS DISEASES; AUSTRALIA; COMORBIDITY; HUMANS; INCIDENCE; MALE; MIDDLE AGED; PROSTATIC NEOPLASMS; RADIATION INJURIES; RADIOTHERAPY, CONFORMAL; RECTAL DISEASES; RISK ASSESSMENT; RISK FACTORS; TREATMENT OUTCOME;

EID: 57649083010     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2008.03.058     Document Type: Article

References (31)

1. Yeoh E.K., Russo A., Botten R., et al. Acute effects of therapeutic irradiation for prostatic carcinoma on anorectal function. Gut 43 (1998) 123-127
2. Sedgwick D.M., Howard G.C.W., and Ferguson A. Pathogenesis of acute radiation injury to the rectum: A prospective study in patients. Int J Colorect Dis 9 (1994) 23-30
3. Hanks G.E. External beam radiation therapy for clinically localised prostate cancer: Patterns of care studies in the United States. NCI Monogr 7 (1988) 75-84
4. Perez C.A., Lee H.K., Georgion A., et al. Technical factors affecting morbidity in definitive irradiation for localized carcinoma of the prostate. Int J Radiat Oncol Biol Phys 28 (1994) 811-819
5. Widmark A., Fransson P., and Tavelin B. Self-assessment questionnaire for evaluating urinary and intestinal late side effects after pelvic radiotherapy in patients with prostate cancer compared with an age-matched control population. Cancer 74 (1994) 2520-2532
6. Yeoh E., Botten R., Russo A., et al. Chronic effects of therapeutic irradiation for localized prostatic carcinoma on anorectal function. Int J Radiat Oncol Biol Phys 47 (2000) 915-924
7. Franklin C.I.V., Parker C.A., and Morton K.M. Late effects of radiation therapy for prostate carcinoma: The patient's perspective of bladder, bowel and sexual morbidity. Aust Radiol 42 (1998) 58-65
8. Denham J.W., O'Brien P.C., Dunstan R.H., et al. Is there more than one late radiation proctitis syndrome?. Radiother Oncol 51 (1999) 43-53
9. Yeoh E.K., Fraser R.J., McGowan R., et al. Evidence for efficacy without increased toxicity of hypofractionated radiation therapy for prostate carcinoma. Int J Radiat Oncol Biol Phys 55 (2003) 943-955
10. Yeoh E., Holloway R., Fraser R., et al. Hypofractionated vs. conventionally fractionated radiation therapy for prostate carcinoma: Updated results of a Phase III randomised trial. Int J Radiat Oncol Biol Phys 66 (2006) 1072-1083
11. Dearnaley D.P., Khoo V.S., Norman A.R., et al. Comparison of radiation side effects of conformal and conventional radiotherapy in prostate cancer: A randomised trial. Lancet 353 (1999) 267-272
12. Pollack A., Zagars G.K., Starkschall G., et al. Prostate cancer radiation dose response: Results of the MD Anderson Phase III randomized trial. Int J Radiat Oncol Biol Phys 53 (2002) 1097-1105
13. Dearnaley D.P., Sydes M.R., Graham J.D., et al. Escalated-dose vs. standard-dose conformal radiotherapy in prostate cancer: First results from the MRC RT01 randomised controlled trial. Lancet Oncol 8 (2007) 475-487
14. Eisenberger M., and Partin A. Progress toward identifying aggressive prostate cancer. [Editorial]. N Engl J Med 351 (2004) 100-181
15. Penson D.F., Litwin M.S., and Aaronson N.K. Health related quality of life in men with prostate cancer. J Urol 169 (2003) 1653-1661
16. Varma J.S., Smith A.N., and Busuttil A. Correlation of clinical and manometric abnormalities of rectal function following chronic radiation injury. Br J Surg 72 (1985) 875-878
17. Varma J.S., Smith A.N., and Busuttil A. Function of the anal sphincters after chronic radiation injury. Gut 27 (1986) 528-533
18. Yeoh E., Holloway R., Fraser R., et al. Anorectal dysfunction increases with time following radiation therapy for carcinoma of the prostate. Am J Gastrenterol 99 (2004) 361-369
19. Sun W.M., Read N.W., Prior A., et al. Sensory and motor response to rectal distension vary according to rate and pattern of balloon inflation. Gastroenterology 99 (1990) 1008-1015
20. Read N.W., and Sun W.M. Disordered anorectal motor function. Balleries Clin Gastroenterol 5 (1991) 479-504
21. Cohen J. Comparing two means. In: Machin D., and Campbell M.J. (Eds). Statistical tables for the design of clinical trials (1987), Blackwell Scientific Publications, Oxford, UK 79-88
22. Livsey J., Routledge J., Burns M., et al. Scoring of treatment-related late effects in prostate cancer. Radiother Oncol 65 (2002) 109-121
23. Sale C., Yeoh E., Scutter S., and Bezak E. 2D vs 3D radiation therapy for prostate carcinoma: A direct comparison of dose volume histograms. Acta Oncol 44 (2005) 3348-3354
24. Dawson L.A., Mah K., Franssen E., and Morton G. Target position variability throughout prostate radiotherapy. Int J Radiat Oncol Biol Phys 42 (1998) 1155-1161
25. Zelefsky M.J., Crean D., Mageras G.S., et al. Quantification and predictors of prostate position variability in patients evaluated with multiple CT scans during conformal radiotherapy. Radiother Oncol 50 (1999) 225-234
26. Smitsmans M.H.P., De Bois J., Sonke J.-J., et al. Automatic prostate localization on cone-beam CT scans for high precision image-guided radiotherapy. Int J Radiat Oncol Biol Phys 63 (2005) 975-984
27. Hsu I.C., Pickett B., Shinohara K., et al. Normal tissue dosimetric comparison between HDR prostate implant boost and conformal external beam radiotherapy boost: Potential for dose escalation. Int J Radiat Oncol Biol Phys 46 (2000) 851-858
28. Vordermark D., Schwab M., Ness D.R., et al. Association of anorectal dose volume histograms and impaired fecal continence after 3D conformal radiotherapy for carcinoma of the prostate. Radiother Oncol 69 (2003) 209-214
29. Fodkal L., Honore H., Hoyer M., and von der Maase H. Dose volume histograms associated to long term colorectal functions in patients receiving pelvis radiotherapy. Radiother Oncol 74 (2005) 203-210
30. al-Abany M., Helgason A.R., Cronqvist A.K.A., et al. Toward a definition of a threshold for harmless doses to the anal sphincter region and the rectum. Int J Radiat Oncol Biol Phys 61 (2005) 1035-1044
31. Peeters S.T.H., Lebesque J.V., Heemsbergen W.D., et al. Localized volume effects for late rectal and anal toxicity after radiotherapy for prostate cancer. Int J Radiat Oncol Biol Phys 64 (2006) 1151-1161