Studies of meconium-induced lung injury: Inflammatory cytokine expression and apoptosis

Journal of Perinatology

Volumn 28, Issue , 2008, Pages S102-S107

  Vidyasagar, D ^a   Zagariya, A ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTITRYPSIN; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR; CAPTOPRIL; CASPASE 3; CYTOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 8; NITRIC OXIDE; PHOSPHOLIPASE; REACTIVE OXYGEN METABOLITE; SERINE PROTEINASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; COMPLEMENT ACTIVATION; CONFERENCE PAPER; CYTOKINE PRODUCTION; CYTOKINE RELEASE; HUMAN; INFLAMMATION; LUNG ALVEOLUS EPITHELIUM; LUNG ALVEOLUS MACROPHAGE; LUNG INJURY; MECONIUM ASPIRATION; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PROTEIN EXPRESSION; RECEPTOR BINDING;

ANGIOTENSIN II; ANIMALS; APOPTOSIS; CYTOKINES; HUMANS; INFANT, NEWBORN; LUNG; MECONIUM; MECONIUM ASPIRATION SYNDROME; SERPINS;

EID: 57549093049     PISSN: 07438346     EISSN: 14765543     Source Type: Journal    
DOI: 10.1038/jp.2008.153     Document Type: Review

References (39)

1. Vidyasagar D, Yeh TF, Harris MD, Pildes RS. Assisted ventilation in infants with meconium aspiration syndrome. Pediatrics 1975; 56(2): 208–213.
2. Shrinivasan HB, Vidyasagar D. Meconium aspiration syndrome: current concepts and management. Compr Ther 1999; 25(2): 82–89.
3. Tyler DC, Murphy J, Cheney FW. Mechanical and chemical damage to lung tissue caused by meconium aspiration. Pediatrics 1978; 62: 454–459.
4. Jones CA, Cayabyab RG, Kwong KY, Stotts C, Wong B, Hamdan H et al. Undetectable interleukin (IL)-10 and persistent IL-8 expression early in hyaline membrane disease: a possible development basis for the predisposition to chronic lung inflammation in preterm infants. Pediatr Res 1996; 39: 966–975.
5. Holopainen R, Soukka H, Kaapa P. Meconium aspiration induced a concentration-dependent pulmonary hypertension in newborn piglets. Pediatr Pulmonol 1998; 25: 107–113.
6. Zagariya A, Doherty J, Bhat R, Navale S, McMillan M, Uhal B et al. Elevated immunoreactive level of ET-1 levels in newborn rabbit lungs after meconium aspiration. Pediatr Crit Care Med 2002; 3(3): 297–302.
7. Soukka H, Viinikka L, Kaapa P. Involvement of thromboxane A2 prostacyclyn in the early pulmonary hypertension after porcine meconium aspiration. Pediatr Res 1998; 44(6): 838–842.
8. de Beaufort AJ, Pelikan DM, Elferink JG, Berger HM. Effect of interleukin 8 in meconium on in-vitro neutrophil chemotaxis. Lancet 1998; 352(9122): 102–105.
9. Uotila PJ, Kaapa PO. Cyclooxygenase-2 expression in human monocytes stimulated by meconium. Lancet 1998; 351: 978.
10. Castellheim A, Lindenskov PH, Pharo A, Fung M, Saugstad OD, Mollnes TE. Meconium is a potent activator of complement in human serum and in piglets. Pediatr Res 2004; 55(2): 310–318.
11. Davey AM, Becker JD, Davies JM. Meconium aspiration syndrome: physiological and inflammatory changes in the newborn piglet model. Pediatr Pulmonol 1993; 16: 101–108.
12. Holopainen R, Aho H, Laine J, Peuravuori H, Soukka H, Kaapa P. Human meconium has high phospholipase A2 activity and induced cellular injury and apoptosis in piglets lungs. Pediatr Res 1999; 46: 626–632.
13. Mollnes TE, Song WC, Lambris JD. Complement in inflammatory tissue damage and disease. Trends Immunol 2002; 23(2): 61–64.
14. Khan AM, Elidemir O, Epstein CE, Lally KP, Xue H, Blackburn M et al. Meconium aspiration produces airway hyperresponsiveness and eosinophilic inflammation in a murine model. Am J Physiol Lung Cell Mol Physiol 2002; 283(4): L785–L790.
15. Zagariya A, Bhat R, Navale S, Vidyasagar D. Cytokine expression in meconium-induced lungs. Indian J Pediatr 2004; 71(3): 195–201.
16. Zagariya A, Bhat R, Uhal B, Navale S, Freidine M, Vidyasagar D. Cell death and lung cell histology in meconium aspirated newborn rabbit lung. Eur J Pediatr 2000; 159(11): 819–826.
17. Tessler R, Pan J, Fiori HH, Belik J. Human meconium has a pulmonary vascular and airway smooth muscle relaxant effect. Pediatr. Res 2008; 64(1): 24–28.
18. Kojima T, Hattori K, Fujuwara T, Takedatsu-Sasai M, Kobayashi Y. Meconium-induced lung injury mediated by activation of alveolar macrophages. Life Sci 1994; 54: 1559–1562.
19. Soukka HR, Ahotupa M, Ruutu M, Kaapa PO. Meconium stimulates neutrophil oxidative burst. Am J Perinatol 2002; 19(5): 279–284.
20. Korhonen K, Soukka H, Halkola L, Peuravuori H, Aho H, Pulkki K et al. Meconium induces only localized inflammatory lung injury in piglets. Pediatr Res 2003; 54(2): 192–197.
21. Fijishima S, Aikawa N. Neutrophil-mediated tissue injury and its modulation. Intensive Care Med 1995; 21: 277–285.
22. Holopainen R, Soukka H, Halkola L, Kaapa P. Intravenous immunoglobulin G attenuates pulmonary hypertension but induces local neutrophil influx in meconium aspiration in piglets. Biol Neonate 2005; 87: 221–228.
23. Ruiz de Souza V, Carreno MP, Kaveri SV, Ledur A, Sadeghi H, Cavaillon JM et al. Selective induction of interleukin-1 receptor antagonist and interleukin-8 in human monocytes by normal polyspecific IgG (intravenous immunoglobulin). Eur J Immunol 1995; 25: 1267–1273.
24. Baggiolini M, Loetcher P. Chemokines in inflammation and immunity. Immunol Today 2000; 21: 418–420.
25. Lopez A, Bildfell R. Pulmonary inflammation associated with aspirated meconium and epithelial cells in calves. Vet Pathol 1992; 29: 104–111.
26. Kaapa P. Meconium aspiration syndrome: a role for phospholipase A2 in the pathogenesis? Acta Paediatr 2001; 90: 365–367.
27. Bardales RH, Xie SS, Schaefer RF, Hsu SM. Apoptosis is a major pathway responsible for the resolution of type II pneumocytes in acute lung injury. Am J Pathol 1996; 149: 845–852.
28. Zagariya A, Bhat R, Chari G, Uhal B, Navale S, Vidyasagar D. Apoptosis of airway epithelial cells in response to meconium. Life Sci 2005; 76(16): 1849–1858.
29. Kazzas JA, Xu J, Palaia TA, Mantel L, Fein AM, Horowitz S. Cellular oxygenotoxicity. Oxidant injury without apoptosis. J Biol Chem 1996; 271: 15182–15186.
30. Gaboury J, Woodman RC, Granger DN, Reinhardt P, Kubes P. Nitric oxide prevents leukocyte adherence: roleof superoxyde. Am J Physiol 1993; 265(3 pt 2): H862–H867.
31. Brune B, von Knethen A, Sanday KB. Nitric oxide and its role in apoptosis. Eur J Pharmacol 1998; 351: 261–272.
32. Janssen YMW, Matalon S, Mossman BT. Differential induction of c-fos, c-jun, and apoptosis in lung epithelial cells exposed to ROS or RNS. Am J Physiol 1997; 273(4 Pt 1): L789–L796.
33. Narula P, Xu J, Kazzaz A, Robbins CG, Davis JM, Horowitz S. Synergistic cytotoxicity from nitric oxide and hyperoxia in cultured lung cells. Am J Physiol 1998; 274: L411–L416.
34. Wang R, Zagariya A, Ang E, Ibarra-Sunga O, Uhal B. FAS-induced apoptosis of alveolar epithelial cells require angiotensinogen II generation and receptor interaction. Am J Physiol Lung Cell Mol Physiol 1999; 277: L1245–L1250.
35. Wang R, Alam G, Zagariya A, Gidea C, Pinillos H, Lalude O et al. Apoptosis of lung epithelial cells in response to TNFa requires Angiotensin II generation de novo. J Cell Physiol 2000; 185: 253–259.
36. Wang R, Zagariya A, Ibarra-Sunga O, Gidea C, Ang E, Deshmukh S et al. Angiotensin II induced apoptosis in human and rat alveolar epithelial cells. Am J Physiol 1999; 276: L885–L889.
37. Zagariya A, Uhal B, Navale S, Vidyasagar D. Inhibition of Meconium Induced Lung Cell Apoptosis by Captopril. Pediatric Academic Societies and American Academy of Pediatrics Joint Meeting, Boston, MA 2000, Abstract.
38. Zagariya A, Bhat R, Uhal B, Navale S, Vidyasagar D. Captopril Inhibits Meconium Induced Cytokines Expression and Lung Cell Apoptosis, Pediatric Academic Societies Meeting, Philadelphia, PA 2001, Abstract.
39. Zagariya AM, Bhat R, Zhabotynsky E, Chari G, Navale S, Xu Q et al. Characterization of serine/cysteine protease inhibitor alpha1-antitripsin from meconium-instilled rabbit lungs. J Cell Biochem 2005; 96(1): 137–144.