-
1
-
-
37849000966
-
Tandutinib, an oral, small-molecule inhibitor of FLT3 for the treatment of AML and other cancer indications
-
Cheng, Y. Paz, K. (2008) Tandutinib, an oral, small-molecule inhibitor of FLT3 for the treatment of AML and other cancer indications. IDrugs, 11, 46 56.
-
(2008)
IDrugs
, vol.11
, pp. 46-56
-
-
Cheng, Y.1
Paz, K.2
-
2
-
-
24144452797
-
Signal transduction of oncogenic Flt3
-
Choudhary, C., Müller-Tidow, C., Berdel, W.E. Serve, H. (2005) Signal transduction of oncogenic Flt3. International Journal of Hematology, 82, 93 99.
-
(2005)
International Journal of Hematology
, vol.82
, pp. 93-99
-
-
Choudhary, C.1
Müller-Tidow, C.2
Berdel, W.E.3
Serve, H.4
-
3
-
-
0033607203
-
Multiple in vivo tyrosine phosphorylation sites in EphB receptors
-
Kalo, M.S. Pasquale, E.B. (1999) Multiple in vivo tyrosine phosphorylation sites in EphB receptors. Biochemistry, 38, 14396 14408.
-
(1999)
Biochemistry
, vol.38
, pp. 14396-14408
-
-
Kalo, M.S.1
Pasquale, E.B.2
-
4
-
-
34548691437
-
Sensitivity toward sorafenib and sunitinib varies between different activating and drug-resistant FLT3-ITD mutations
-
Kancha, R.K., Grundler, R., Peschel, C. Duyster, J. (2007) Sensitivity toward sorafenib and sunitinib varies between different activating and drug-resistant FLT3-ITD mutations. Experimental Hematology, 35, 1522 1526.
-
(2007)
Experimental Hematology
, vol.35
, pp. 1522-1526
-
-
Kancha, R.K.1
Grundler, R.2
Peschel, C.3
Duyster, J.4
-
6
-
-
0037186464
-
Bis(1H-2-indolyl)methanones as a novel class of inhibitors of the platelet-derived growth factor receptor kinase
-
Mahboobi, S., Teller, S., Pongratz, H., Hufsky, H., Sellmer, A., Botzki, A., Uecker, A., Beckers, T., Baasner, S., Schächtele, C., Überall, F., Kassack, M.U., Dove, S. Böhmer, F.D. (2002) Bis(1H-2-indolyl)methanones as a novel class of inhibitors of the platelet-derived growth factor receptor kinase. Journal of Medicinal Chemistry, 45, 1002 1018.
-
(2002)
Journal of Medicinal Chemistry
, vol.45
, pp. 1002-1018
-
-
Mahboobi, S.1
Teller, S.2
Pongratz, H.3
Hufsky, H.4
Sellmer, A.5
Botzki, A.6
Uecker, A.7
Beckers, T.8
Baasner, S.9
Schächtele, C.10
Überall, F.11
Kassack, M.U.12
Dove, S.13
Böhmer, F.D.14
-
7
-
-
33744785117
-
Novel bis(1H-indol-2-yl)methanones as potent inhibitors of FLT3 and platelet-derived growth factor receptor tyrosine kinase
-
Mahboobi, S., Uecker, A., Sellmer, A., Cenac, C., Hocher, H., Pongratz, H., Eichhorn, E., Hufsky, H., Trümpler, A., Sicker, M., Heidel, F., Fischer, T., Stocking, C., Elz, S., Böhmer, F.D. Dove, S. (2006) Novel bis(1H-indol-2-yl)methanones as potent inhibitors of FLT3 and platelet-derived growth factor receptor tyrosine kinase. Journal of Medicinal Chemistry, 49, 3101 3115.
-
(2006)
Journal of Medicinal Chemistry
, vol.49
, pp. 3101-3115
-
-
Mahboobi, S.1
Uecker, A.2
Sellmer, A.3
Cenac, C.4
Hocher, H.5
Pongratz, H.6
Eichhorn, E.7
Hufsky, H.8
Trümpler, A.9
Sicker, M.10
Heidel, F.11
Fischer, T.12
Stocking, C.13
Elz, S.14
Böhmer, F.D.15
Dove, S.16
-
8
-
-
0038204144
-
SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo
-
O'Farrell, A.M., Abrams, T.J., Yuen, H.A., Ngai, T.J., Louie, S.G., Yee, K.W., Wong, L.M., Hong, W., Lee, L.B., Town, A., Smolich, B.D., Manning, W.C., Murray, L.J., Heinrich, M.C. Cherrington, J.M. (2003) SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo. Blood, 101, 3597 3605.
-
(2003)
Blood
, vol.101
, pp. 3597-3605
-
-
O'Farrell, A.M.1
Abrams, T.J.2
Yuen, H.A.3
Ngai, T.J.4
Louie, S.G.5
Yee, K.W.6
Wong, L.M.7
Hong, W.8
Lee, L.B.9
Town, A.10
Smolich, B.D.11
Manning, W.C.12
Murray, L.J.13
Heinrich, M.C.14
Cherrington, J.M.15
-
9
-
-
2442558941
-
Flt3 receptor tyrosine kinase as a drug target in leukemia
-
Schmidt-Arras, D., Schwäble, J., Böhmer, F.D. Serve, H. (2004) Flt3 receptor tyrosine kinase as a drug target in leukemia. Current Pharmaceutical Design, 10, 1867 1883.
-
(2004)
Current Pharmaceutical Design
, vol.10
, pp. 1867-1883
-
-
Schmidt-Arras, D.1
Schwäble, J.2
Böhmer, F.D.3
Serve, H.4
-
10
-
-
17644388474
-
Tyrosine phosphorylation regulates maturation of receptor tyrosine kinases
-
Schmidt-Arras, D.E., Böhmer, A., Markova, B., Choudhary, C., Serve, H. Böhmer, F.D. (2005) Tyrosine phosphorylation regulates maturation of receptor tyrosine kinases. Molecular and Cellular Biology, 25, 3690 3703.
-
(2005)
Molecular and Cellular Biology
, vol.25
, pp. 3690-3703
-
-
Schmidt-Arras, D.E.1
Böhmer, A.2
Markova, B.3
Choudhary, C.4
Serve, H.5
Böhmer, F.D.6
-
11
-
-
0141465061
-
The role of FLT3 in haematopoietic malignancies
-
Stirewalt, D.L. Radich, J.P. (2003) The role of FLT3 in haematopoietic malignancies. Nature Reviews Cancer, 3, 650 665.
-
(2003)
Nature Reviews Cancer
, vol.3
, pp. 650-665
-
-
Stirewalt, D.L.1
Radich, J.P.2
-
12
-
-
0035984518
-
Bis(1H-2-indolyl)-1-methanones as inhibitors of the hematopoietic tyrosine kinase Flt3
-
Teller, S., Kramer, D., Böhmer, S.A., Tse, K.F., Small, D., Mahboobi, S., Wallrapp, C., Beckers, T., Kratz-Albers, K., Schwäble, J., Serve, H. Böhmer, F.D. (2002) Bis(1H-2-indolyl)-1-methanones as inhibitors of the hematopoietic tyrosine kinase Flt3. Leukemia, 16, 1528 1534.
-
(2002)
Leukemia
, vol.16
, pp. 1528-1534
-
-
Teller, S.1
Kramer, D.2
Böhmer, S.A.3
Tse, K.F.4
Small, D.5
Mahboobi, S.6
Wallrapp, C.7
Beckers, T.8
Kratz-Albers, K.9
Schwäble, J.10
Serve, H.11
Böhmer, F.D.12
-
13
-
-
33645116285
-
Emerging Flt3 kinase inhibitors in the treatment of leukaemia
-
Tickenbrock, L., Müller-Tidow, C., Berdel, W.E. Serve, H. (2006) Emerging Flt3 kinase inhibitors in the treatment of leukaemia. Expert Opinion Emerging Drugs, 11, 153 165.
-
(2006)
Expert Opinion Emerging Drugs
, vol.11
, pp. 153-165
-
-
Tickenbrock, L.1
Müller-Tidow, C.2
Berdel, W.E.3
Serve, H.4
-
14
-
-
0033538676
-
A dual inhibitor of platelet-derived growth factor beta-receptor and Src kinase activity potently interferes with motogenic and mitogenic responses to PDGF in vascular smooth muscle cells. a novel candidate for prevention of vascular remodeling
-
Waltenberger, J., Uecker, A., Kroll, J., Frank, H., Mayr, U., Bjorge, J.D., Fujita, D., Gazit, A., Hombach, V., Levitzki, A. Böhmer, F.D. (1999) A dual inhibitor of platelet-derived growth factor beta-receptor and Src kinase activity potently interferes with motogenic and mitogenic responses to PDGF in vascular smooth muscle cells. A novel candidate for prevention of vascular remodeling. Circulation Research, 85, 12 22.
-
(1999)
Circulation Research
, vol.85
, pp. 12-22
-
-
Waltenberger, J.1
Uecker, A.2
Kroll, J.3
Frank, H.4
Mayr, U.5
Bjorge, J.D.6
Fujita, D.7
Gazit, A.8
Hombach, V.9
Levitzki, A.10
Böhmer, F.D.11
|