Tissue plasminogen activator enhances the hypoxia/reoxygenation-induced impairment of the blood-brain barrier in a primary culture of rat brain endothelial cells

Cellular and Molecular Neurobiology

Volumn 28, Issue 8, 2008, Pages 1139-1146

  Hiu, Takeshi ^a   Nakagawa, Sinsuke ^a,b   Hayashi, Kentaro ^a   Kitagawa, Naoki ^a   Tsutsumi, Keisuke ^a   Kawakubo, Junichi ^a   Honda, Masaru ^a   Suyama, Kazuhiko ^a   Nagata, Izumi ^a   Niwa, Masami ^a,b  

^a NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

^b PharmaCo Cell Co Ltd   (Japan)

Author keywords

Blood brain barrier; Brain capillary endothelial cells (rat); Hypoxia reoxygenation (in vitro); Tight junction; Tissue plasminogen activator; Transendothelial electrical resistance; Transendothelial permeability

Indexed keywords

EVANS BLUE; FLUORESCEIN SODIUM; LUCIFER YELLOW; PROTEIN ZO1; TISSUE PLASMINOGEN ACTIVATOR;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ARTICLE; BLOOD BRAIN BARRIER; BRAIN; CELL TRANSPORT; CONTROLLED STUDY; ELECTRIC RESISTANCE; ENDOTHELIUM CELL; HYPOXIA; NONHUMAN; PERMEABILITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REOXYGENATION;

ANIMALS; BLOOD-BRAIN BARRIER; CELL HYPOXIA; CELL SURVIVAL; CELLS, CULTURED; ELECTRIC IMPEDANCE; ENDOTHELIAL CELLS; FLUORESCEIN; HUMANS; IMMUNOHISTOCHEMISTRY; ISOQUINOLINES; MEMBRANE PROTEINS; OXYGEN; PERMEABILITY; PHOSPHOPROTEINS; RATS; TIME FACTORS; TISSUE PLASMINOGEN ACTIVATOR;

RATTUS;

EID: 57449101902     PISSN: 02724340     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10571-008-9294-x     Document Type: Article

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