Understanding the solid-state forms of fenofibrate - A spectroscopic and computational study

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 71, Issue 1, 2009, Pages 100-108

  Heinz, Andrea ^a,b   Gordon, Keith C ^a   McGoverin, Cushla M ^a   Rades, Thomas ^a   Strachan, Clare J ^b  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Amorphous; Density functional theory; Infrared spectroscopy; Metastable; Polymorphism; Principal component analysis; Raman spectroscopy; Recrystallization

Indexed keywords

BENZENE DERIVATIVE; DIMER; FENOFIBRATE; MONOMER;

ARTICLE; CHEMICAL BOND; CRYSTALLIZATION; DRUG CONFORMATION; DRUG DOSAGE FORM; MOLECULAR INTERACTION; QUANTUM CHEMISTRY; RAMAN SPECTROMETRY; SOLID STATE;

CHEMISTRY, PHARMACEUTICAL; CRYSTALLIZATION; HYDROGEN BONDING; MODELS, MOLECULAR; MULTIVARIATE ANALYSIS; PROCETOFEN; QUANTUM THEORY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SPECTRUM ANALYSIS, RAMAN; TECHNOLOGY, PHARMACEUTICAL; VIBRATION;

EID: 57449095886     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2008.05.030     Document Type: Article

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