Trifluoromethyl ketones from enolizable carboxylic acids via enediolate trifluoroacetylation/decarboxylation

Journal of Organic Chemistry

Volumn 73, Issue 23, 2008, Pages 9476-9478

  Reeves, Jonathan T ^a   Song, Jinhua J ^a   Tan, Zhulin ^a   Lee, Heewon ^a   Yee, Nathan K ^a   Senanayake, Chris H ^a  

^a BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDS; CARBOXYLATION; CARBOXYLIC ACIDS; CHEMICAL REACTIONS; KETONES; ORGANIC ACIDS; QUENCHING;

AQUEOUS HCL; CHEMICAL EQUATIONS; GOOD YIELDS; REACTION MIXTURES; SINGLE STEPS; TRIFLUORO METHYLS;

ORGANIC COMPOUNDS;

CARBOXYLIC ACID; CARBOXYLIC ACID DERIVATIVE; KETONE DERIVATIVE; TRIFLUOROMETHYLKETONE; UNCLASSIFIED DRUG; ALDEHYDE; CARBON; KETONE;

ACETYLATION; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; CHEMICAL STRUCTURE; DECARBOXYLATION; METABOLISM; ONE POT SYNTHESIS; POLYMERIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; THERMOREGULATION; CHEMICAL MODEL; CHEMISTRY; CHROMATOGRAPHY; ORGANIC CHEMISTRY; PROCEDURES;

ACETYLATION; ALDEHYDES; CARBON; CARBOXYLIC ACIDS; CHEMISTRY, ORGANIC; CHROMATOGRAPHY; DECARBOXYLATION; KETONES; MODELS, CHEMICAL;

EID: 57449092672     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo801737c     Document Type: Article

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