Para-aortic lymphadenectomy improves survival in patients with intermediate to high-risk endometrial carcinoma

Acta Obstetricia et Gynecologica Scandinavica

Volumn 87, Issue 12, 2008, Pages 1361-1369

  Chang, Suk Joon ^a   Kim, Woo Young ^a   Yoon, Jong Hyuck ^a   Yoo, Seung Chul ^a   Chang, Ki Hong ^a   Ryu, Hee Sug ^a  

^a Ajou University School of Medicine   (South Korea)

Author keywords

Endometrial carcinoma; Para aortic lymphadenectomy; Prognosis

Indexed keywords

CISPLATIN; DOXORUBICIN;

ADULT; AGED; ARTICLE; CANCER STAGING; CANCER SURVIVAL; CONTROLLED STUDY; ENDOMETRIUM CARCINOMA; FEMALE; HIGH RISK POPULATION; HUMAN; LYMPHADENECTOMY; MAJOR CLINICAL STUDY; PARAAORTIC LYMPH NODE; PARAAORTIC LYMPHADENECTOMY; PELVIS LYMPHADENECTOMY; PRIORITY JOURNAL;

DISEASE-FREE SURVIVAL; ENDOMETRIAL NEOPLASMS; FEMALE; HUMANS; KAPLAN-MEIERS ESTIMATE; LYMPH NODE EXCISION; LYMPH NODES; LYMPHATIC METASTASIS; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEOPLASM STAGING; PELVIS; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; SURVIVAL RATE;

EID: 57449090948     PISSN: 00016349     EISSN: 16000412     Source Type: Journal    
DOI: 10.1080/00016340802503054     Document Type: Article

References (24)

1. FIGO. Annual report on the results of treatment in gynecologic cancer. Int J Gynecol Obstet. 1989;28:189-93.
2. Homesley HD. Management of endometrial cancer. Am J Obstet Gynecol. 1996;174:529-34.
3. ACOG. ACOG practice bulletin, clinical management guidelines for obstetrician-gynecologists, number 65, August 2005: management of endometrial cancer. Obstet Gynecol. 2005;106:413-25.
4. Kilgore LC, Partridge EE, Alvarez RD, Austin JM, Shingleton HM, Noojin F III, et al. Adenocarcinoma of the endometrium: survival comparisons of patients with and without pelvic node sampling. Gynecol Oncol. 1995;56:29-33.
5. Cragun JM, Havrilesky LJ, Calingaert B, Synan I, Secord AA, Soper JT, et al. Retrospective analysis of selective lymphadenectomy in apparent early-stage endometrial cancer. J Clin Oncol. 2005;23:3668-75.
6. Cosa-NZ-UK Endometrial Cancer Study Groups. Pelvic lymphadenectomy in high risk endometrial cancer. Int J Gynecol Cancer. 1996;6:102-7.
7. Kitchener HC, Redman CW, Swart AM, Amos CL. ASTECA study in the treatment of the endometrial cancer: a randomized trial of lymphadenectomy in the treatment of the endometrial cancer. Gynecol Oncol. 2006;101:S21.
8. Belinson JL, Lee KR, Badger GJ, Pretorius RG, Jarrell MA. Clinical stage I adenocarcinoma of the endometrium - analysis of recurrences and the potential benefit of staging lymphadenectomy. Gynecol Oncol. 1992;44:17-23.
9. Corn BW, Lanciano RM, Greven KM, Schultz DJ, Reisinger SA, Stafford PM, et al. Endometrial cancer with para-aortic adenopathy: patterns of failure and opportunities for cure. Int J Radiat Oncol Biol Phys. 1992;24:223-7.
10. Kim YB, Niloff JM. Endometrial carcinoma: analysis of recurrence in patients treated with a strategy minimizing lymph node sampling and radiation therapy. Obstet Gynecol. 1993;82:175-80.
11. Faught W, Krepart GV, Lotocki R, Heywood M. Should selective paraaortic lymphadenectomy be part of surgical staging for endometrial cancer? Gynecol Oncol. 1994;55:51-5.
12. Mariani A, Webb MJ, Galli L, Podratz KC. Potential therapeutic role of para-aortic lymphadenectomy in node-positive endometrial cancer. Gynecol Oncol. 2000;76:348-56.
13. Hirahatake K, Hareyama H, Sakuragi N, Nishiya M, Makinoda S, Fujimoto S. A clinical and pathologic study on paraaortic lymph node metastasis in endometrial carcinoma. J Surg Oncol. 1997;65:82-7.
14. Mariani A, Keeney GL, Aletti G, Webb MJ, Haddock MG, Podratz KC. Endometrial carcinoma: paraaortic dissemination. Gynecol Oncol. 2004;92:833-8.
15. Chuang L, Burke TW, Tornos C, Marino BD, Mitchell MF, Tortolero-Luna G, et al. Staging laparotomy for endometrial carcinoma: assessment of retroperitoneal lymph nodes. Gynecol Oncol. 1995;58:189-93.
16. Fujimoto T, Nanjyo H, Nakamura A, Yokoyama Y, Takano T, Shoji T, et al. Para-aortic lymphadenectomy may improve disease-related survival in patients with multipositive pelvic lymph node stage IIIc endometrial cancer. Gynecol Oncol. 2007;107:253-9.
17. Morrow CP, Bundy BN, Kurman RJ, Creasman WT, Heller P, Homesley HD, et al. Relationship between surgical-pathological risk factors and outcome in clinical stage I and II carcinoma of the endometrium: a Gynecologic Oncology Group study. Gynecol Oncol. 1991;40:55-65.
18. Chan JK, Cheung MK, Huh WK, Osann K, Husain A, Teng NN, et al. Therapeutic role of lymph node resection in endometrioid corpus cancer: a study of 12,333 patients. Cancer. 2006;107:1823-30.
19. Chan JK, Wu H, Cheung MK, Shin JY, Osann K, Kapp DS. The outcomes of 27,063 women with unstaged endometrioid uterine cancer. Gynecol Oncol. 2007;106:282-8.
20. Smith DC, Macdonald OK, Lee CM, Gaffney DK. Survival impact of lymph node dissection in endometrial adenocarcinoma: a surveillance, epidemiology, and end results analysis. Int J Gynecol Cancer. 2008;18:255-61.
21. Randall ME, Filiaci VL, Muss H, Spirtos NM, Mannel RS, Fowler J, et al. Randomized phase III trial of whole-abdominal irradiation versus doxorubicin and cisplatin chemotherapy in advanced endometrial carcinoma: a Gynecologic Oncology Group Study. J Clin Oncol. 2006;24:36-44.
22. Geisler JP, Linnemeier GC, Manahan KJ. Pelvic and para-aortic lymphadenectomy in patients with endometrioid adenocarcinoma of the endometrium. Int J Gynaecol Obstet. 2007;98:39-43.
23. Mariani A, Dowdy SC, Cliby WA, Gostout BS, Jones MB, Wilson TO, et al. Prospective assessment of lymphatic dissemination in endometrial cancer: a paradigm shift in surgical staging. Gynecol Oncol. 2008;109:11-18.
24. Bakkum-Gamez JN, Gonzalez-Bosquet J, Laack NN, Mariani A, Dowdy SC. Current issues in the management of endometrial cancer. Mayo Clin Proc. 2008;83:97-112.