Modulation of cathepsin D routing by IGF-II involves IGF-II binding to IGF-II/M6P receptor in MCF-7 breast cancer cells

Growth Factors

Volumn 22, Issue 3, 2004, Pages 169-177

  Faridi, Jesika S ^a   Mohan, Subburaman ^a,b   De León, Daisy D ^a  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Breast cancer; Cathepsin D; Insulin like growth factor II; Insulin like growth factor II mannose 6 phosphate receptor; MCF 7

Indexed keywords

ARGININE; CATHEPSIN D; MESSENGER RNA; SOMATOMEDIN B; SOMATOMEDIN B RECEPTOR;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BREAST CANCER; CANCER CELL; CELL STRAIN MCF 7; CONTROLLED STUDY; ENZYME RELEASE; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN CELL; HYPOTHESIS; MOUSE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN SECRETION; RADIOIMMUNOASSAY; RECEPTOR BINDING; REGULATORY MECHANISM; WESTERN BLOTTING;

ANIMALS; ARGININE; BLOTTING, NORTHERN; BLOTTING, WESTERN; BREAST NEOPLASMS; CATHEPSIN D; CELL LINE; CELL LINE, TUMOR; CULTURE MEDIA, CONDITIONED; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; GENETIC VECTORS; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; INSULIN-LIKE GROWTH FACTOR II; LYSOSOMES; MICE; MICROSOMES, LIVER; RADIOIMMUNOASSAY; RNA, MESSENGER; TIME FACTORS; TRANSFECTION;

MINK CELL FOCUS-FORMING VIRUS;

EID: 5744252440     PISSN: 08977194     EISSN: None     Source Type: Journal    
DOI: 10.1080/08977190410001725531     Document Type: Article

References (34)

1. Brouillet, J.P., Spyratos, F., Hacene, K., Fauque, J., Freiss, G., Dupont, F., Maudelonde, T. and Rochefort, H. (1993) "Immunoradiometric assay of pro-cathepsin D in breast cancer cytosol: relative prognostic value versus total cathepsin D", Eur. J. Cancer 29A, 1248-1251.
2. Capony, F., Morisset, M., Barrett, A.J., Capony, J.P., Broquet, P., Vignon, F., et al. (1987) "Phosphorylation, glycosylation and proteolytic activity of the 52 K estrogen-induced protein secreted by MCF7 cells", J. Cell Biol. 104, 253-262.
3. Capony, F., Rougeot, C., Montcourrier, P., Cavailles, V., Salazar, G. and Rochefort, H. (1989) "Increased secretion, altered processing, and glycosylation of pro-cathepsin D in human mammary cancer cells", Cancer Res. 49, 3904-3909.
4. Cavailles, V., Garcia, M. and Rochefort, H. (1989) "Regulation of cathepsin D and pS2 gene expression by growth factors in MCF7 human breast cancer cells", Mol. Endocrinol. 3, 552-558.
5. Chomczynski, P. (1993) "A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples", Biotechniques 15, 532-537.
6. Chomczynski, P. and Sacchi, N. (1987) "Single step method of RNA isolation by guanidinium thiocyanate-phenol-chloroform extraction", Anal. Biochem. 162, 156-159.
7. Cullen, K.J., Yee, D., Sly, W.S., Perdue, J., Hampton, B., Lippman, M.E. and Rosen, N. (1990) "Insulin-like growth factor receptor expression and function in human breast cancer", Cancer Res. 50, 45-48.
8. Cullen, K.J., Lippman, M.E., Chow, D., Hill, S., Rosen, N. and Zwiebel, J.A. (1992) "Insulin-like growth factor-II overexpression in MCF-7 cells induces phenotypic changes associated with malignant progression", Mol. Endocrinol. 6, 91-100.
9. DaCosta, S.A., Schumaker, L.M. and Ellis, M.J. (2000) "Mannose 6-phosphate/insulin-like growth factor 2 receptor, a bona fide tumor suppressor gene or just a promising candidate?", J. Mammary Gland Biol. Neoplasia 5, 85-94.
10. De León, D.D., Terry, C., Asmerom, Y. and Nissley, P. (1996) "Insulin-like growth factor II modulates the routing of cathepsin D in MCF-7 breast cancer cells", Endocrinology 137, 1851-1859.
11. De León, D.D., Issa, N., Nainani, S. and Asmeron, Y. (1999) "Reversal of cathepsin D routing modulation in MCF-7 breast cancer cells expresing antisense insulin-like growth factor II (IGF-II)", Horm. Metab. Res. 31, 142-147.
12. Ellis, M.J.C., Leav, B.A., Yang, Z., Rasmussen, A., Pearce, A., Zweibel, J.A., Lippman, M.E. and Cullen, K.J. (1996) "Affinity for the insulin-like growth factor-II (IGF-II) receptor inhibits autocrine IGF-II activity in MCF-7 breast cancer cells", Mol. Endocrinol. 10, 286-297.
13. Gabel, C.A., Goldberg, D.E. and Kornfeld, S. (1983) "Identification and characterization of cells deficient in the mannose-6-phosphate receptor: evidence for an alternate pathway for lysosomal enzyme targeting", Proc. Natl Acad. Sci. USA 80, 775-779.
14. Garmroudi, F., Devi, G., Slentz, D., Scaffer, B. and MacDonald, R. (1996) "Truncated forms of the Insulin-like growth factor (IGF-II)/mannose 6-phosphate receptor encompassing the IGF-II binding site: characterization of a point mutation that abolishes IGF-II binding", Mol. Endocrinol. 10, 642-651.
15. Gebauer, G., Jager, W. and Lang, N. (1998) "mRNA Expression of Components of the insulin-like growth factor system in breast cancer cell lines, tissues, and metastatic breast cancer cells", Anticancer Res. 18, 1191-1196.
16. Gion, M., Mione, R., Pappagallo, G.L., Gatti, C., Nascimben, O. and Sampognaro, Meo, S. (1994) "Biochemical parameters for prognostic evaluation in patients with breast cancer", Anticancer Res. 14, 693-698.
17. Hankins, G.R., De Souza, A.T., Bentley, R.C., Patel, M.R., Marks, J.R., Iglehart, J.D. and Jirtle, R.L. (1996) "M6P/IGF-II receptor: a candidate breast tumor suppressor gene", Oncogene 12, 2003-2009.
18. Kiess, W., Thomas, C.L., Greenstein, L.A., Lee, L., Sklar, M.M., Rechler, M.M., Sahagian, G.G. and Nissley, S.P. (1989) "Insulin-like growth factor-II (IGF-II) inhibits both the cellular uptake of β-galactosidase and the binding of β-galactosidase to purified IGF-II/mannose 6-phosphate receptor", J. Biol. Chem. 264, 4710-4714.
19. Kiess, W., Thomas, C.L., Sklar, M.M. and Nissley, S.P. (1990) "Beta-galactosidase decreases the binding affinity of the insulin-like growth factor-II/mannose 6-phosphate receptor for the insulin like growth factor II", Eur. J. Biochem. 190, 71-77.
20. Kornfeld, S. (1992) "Structure and function of the mannose 6-phosphate/insulin-like growth factor II receptors", Annu. Rev. Biochem. 61, 307-330.
21. 1 cells following gene transfer", J. Biol. Chem. 263, 16230-16235.
22. Lobel, P., Fujimoto, K., Ye, R.D., Griffiths, G. and Kornfeld, S. (1989) "Mutations in the cytoplasmic domain of the 275 kDa mannose 6-phosphate receptor differentially alter lysosomal enzyme sorting and endocytosis", Cell 57, 787-796.
23. Mathieu, M., Vignon, F., Capony, F. and Rochefort, H. (1991) "Estradiol down-regulates the mannose-6-phosphate/insulin-like growth factor receptor gene and induces cathepsin D in breast cancer cells: a receptor saturation mechanism to increase the secretion of lysosomal proenzymes", Mol. Endocrinol. 5, 815-882.
24. Mohan, S. and Baylink, D.J. (1995) "Development of a simple valid method for the complete removal of insulin-like growth factor (IGF)-binding proteins from IGFs in human serum and other biological fluids: comparison with acid-ethanol treatment and C18 Sep-Pak separation", J. Clin. Endocinol. Metab. 80, 637-647.
25. Nolan, C.M., Kyle, J.W., Watanabe, H. and Sly, W.S. (1990) "Binding of insulin-like growth factor II (IGF-II) by human cation-independent mannose 6-phosphate receptor/IGF-II receptor expressed in receptor-deficient mouse L cells", Cell Regul. 1, 197-213.
26. Oates, A.J., Schumaker, L.M., Jenkins, S.B., Pearce, A.A., DaCosta, S.A., Arun, B. and Ellis, M.J.C. (1998) "The mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R), a putative breast tumor suppressor gene", Breast Cancer Res. Treat. 47, 269-281.
27. Osborne, C.K., Coronado, E.B., Kitten, L.J., Arteaga, C.I., Fuqua, S.A., Ramasharma, K., Marshall, M. and Li, C.H. (1989) "Insulin-like growth factor-II (IGF-II): a potential autocrine /paracrine growth factor for human breast cancer acting via the IGF-I receptor", Mol. Endocrinol. 3, 1701-1709.
28. Rochefort, H. and Liaudet-Coopman, E. (1999) "Cathepsin D in cancer metastasis: a protease and a ligand", APMIS 107, 86-95.
29. Rochefort, H., Capony, F., Garcia, M., et al. (1987) "Estrogen-induced lysosomal proteases secreted by breast cancer cells. A role in carcinogenesis?", J. Cell Biochem. 35, 17-29.
30. Rochefort, H., Cavailles, V., Augereau, P., Capony, F., Maudelonde, T., Touitou, I., et al. (1989) "Overexpression and hormonal regulation of procathepsin D in mammary and endometrial cancer", J. Steroid Biochem. 34, 177-182.
31. Sakano, K., Enjoh, T., Numata, F., Fujiwara, H., Marumoto, Y., Higashihash, N., Sara, Y., Perdue, J. and Fujita-Yamaguchi, Y. (1991) "The design, expression, and characterization of human insulin-like growth factor-II (IGF-II) mutants specific for either the IGF-II/cation-independent mannose-6-phosphate receptor or IGF-I receptor", J. Biol. Chem. 266, 20626-20635.
32. Riley, L.B., Lange, M.K., Browne, R.J., Cochrane, P.J., Choi, I.J., Davis, B., Arcona, S. and Alhadeff, J.A. (2000) "Analysis of cathepsin D in human breast cancer: usefulness of the processed 31 kDa active form of the enzyme as a prognostic indicator in node-negative and node-positive patients", Breast Cancer Res. Treat. 60, 173-179.
33. Spyratos, F., Brouillet, J.P., Defrenne, A., Hacene, K., Rouesse, J., Maudelonde, T., Brunet, M., Andrieu, C., Displaces, A. and Rochefort, H. (1989) "Cathepsin D: an independent prognostic factor for metastasis of breast cancer", Lancet 2, 1115-1118.
34. Tandon, A.K., Clark, G.M., Chamness, G.C., Chirgwin, J.M. and McGuire, W.L. (1990) "Cathepsin D and prognosis in breast cancer", N. Engl. J. Med. 322, 297-302.