Pellet starters in layering technique using concentrated drug solution

Drug Development and Industrial Pharmacy

Volumn 34, Issue 12, 2008, Pages 1381-1387

  Gryczová, Eva ^a   Rabišková, Miloslava ^a   Vetchý, David ^a   Krejčová, Kateřina ^a  

^a UNIVERSITY OF VETERINARY AND PHARMACEUTICAL SCIENCES   (Czech Republic)

Author keywords

Concentrated drug solution layering; Microcrystalline cellulose; Nonpareils; Pellets; Sucrose

Indexed keywords

CELLET 500; CELPHERE CP 507; LACTOSE; MICROCRYSTALLINE CELLULOSE; POVIDONE; SOLVENT; SUCROSE; UNCLASSIFIED DRUG;

ARTICLE; DRUG SOLUBILITY; FLOW; PELLET EXTRUSION; QUALITY CONTROL; TECHNIQUE;

BIOMECHANICS; CELLULOSE; LACTOSE; PARTICLE SIZE; SOLUTIONS; SUCROSE; TECHNOLOGY, PHARMACEUTICAL;

EID: 57349194301     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.1080/03639040802130046     Document Type: Article

References (14)

1. Clarke, G. M., Newton, J. M., & Short, M. B. (1995). Comparative gastrointestinal transit of pellet systems of varying density. Int. J. Pharm., 114, 1-11.
2. Eichler, K. (2002, October). Qualitative and economical evaluation of the major pharmaceutical pelletizing techniques. 1st Syntapharm Workshop, Kraków.
3. Haznos, L., Langer, I., & Gyamathy, M. (1992). Some factors influencing pellet characteristics made by extrusion/spheronization process: Effect on size characteristics and moisture content decrease of pellets. Drug Dev. Ind. Pharm., 18, 409-437.
4. Heng, P. W. S., & Chan, L. W. (1997). Drug substance and excipient characterization. In D. M. Parikh (Ed.) Handbook of pharmaceutical granulation technology (pp. 25-57). New York, Basel: Marcel Dekker.
5. Jones, D. M. (1989). Solution and suspension layering. In I. Ghebre-Sellassie (Ed.) Pharmaceutical pelletization technology (pp. 145-164). New York, Basel: Marcel Dekker.
6. Kristensen, H. G., & Schaefer, T. (1996). Granulations. In J. Swarbrick & J. C. Boylan (Eds.) Encyclopedia of pharmaceutical technology (Vol. 7, pp. 121-159). New York: Marcel Dekker.
7. Kumar, V., Kohari, S. H., & Banker, G. S. (2001). Compression, compaction, and disintegration properties of low crystallinity celluloses produced using different agitation rates during their regeneration from phosphoric acid solutions. AAPS PharmSciTech 2(2), article 7, pp.7 (Available: http://www.aapspharmscitech.org).
8. Rodriguez, E. C., Torrado, J. J., Nikolakakis, I., Torrado, S., Lastres, J. L., & Malamataris, S. (2001). Micrometric and packing properties of diclofenac pellets and effect of some formulation variables. Drug Dev. Ind. Pharm., 27, 847-855.
9. Rowe, R. C., Sheskey, P. J., & Owen, S. C. (2006). Handbook of pharmaceutical excipients (5th Ed.) (pp. 132-135, 744-746). London: Pharmaceutical Press.
10. Sienkiewicz, G., Pereira, R., Rudnic, E. M., Lausier, J. M., & Rhodes, C. T. (1997). Spheronization of theophylline - Avicel combinations using a fluidized-bed rotogranulation technique. Drug Dev. Ind. Pharm., 23, 173-182.
11. Vertommen, J., & Kinget, R. (1997). The influence of five selected processing and formulation variables on the particle size, particle size distribution, and friability of pellets produced in a rotary processor. Drug Dev. Ind. Pharm., 23, 39-46.
12. Vetchý, D., & Rabišková, M. (2002). Some variables influencing rotoagglomeration in the multiprocessor MP-1. Int. J. Pharm., 242, 353-356.
13. Wan, L. S. C. (1994). Manufacture of core pellets by balling. In I. Ghebre-Sellasie (Ed.) Multiparticulate oral drug delivery (pp. 1-13). New York, Basel: Marcel Dekker.
14. Zhang, Y., Law, Y., & Chakrabarti, S. (2003). Physical properties and compact analysis of commonly used direct compression binders. AAPS PharmSciTech 4(4), article 62, pp.11 (Available: http://www. aapspharmscitech.org).