Ventricular arrhythmias and antioxidative medication: Experimental study

Hellenic Journal of Cardiology

Volumn 49, Issue 5, 2008, Pages 320-328

  Karahaliou, Aggeliki ^a   Katsouras, Christos ^a   Koulouras, Vasileios ^a   Nikas, Dimitrios ^a   Niokou, Dimitra ^a   Papadopoulos, Georgios ^a   Nakos, Georgios ^a   Sideris, Dimitrios ^a   Michalis, Lambros ^a  

^a UNIVERSITY HOSPITAL OF IOANNINA   (Greece)

Author keywords

Ascorbic acid; Coronary artery disease; Deferoxamine; Free oxygen radicals; Ischaemia reperfusion syndrome; Mechanoelectrical interaction; Ventricular arrhythmias

Indexed keywords

ASCORBIC ACID; DEFEROXAMINE; FREE RADICAL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; CORONARY ARTERY LIGATION; HEART VENTRICLE ARRHYTHMIA; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE TACHYCARDIA; ISCHEMIA; MONOTHERAPY; NONHUMAN; REPERFUSION INJURY; SHEEP;

EID: 57349181412     PISSN: 10117970     EISSN: 10117970     Source Type: Journal    
DOI: None     Document Type: Article

References (69)

1. Wiggers CJ. Defibrillation of the ventricles. Circ Res. 1953; 1: 191-199.
2. Davies MJ, Bland JM, Hangarthner JR, Angelini A, Thomas AC. Factors influencing the presence or absence of acute coronary artery thrombi in sudden ischaemic death. Eur Heart J. 1989; 10: 203-208.
3. Engler RL, Dahlgren MD, Morris DD, Petersen MA, Schmid-Schonbein GW. Role of leukocytes in response to acute myocardial ischaemia and reflow in dogs. Am J Physiol. 1986; 251: H314-H322.
4. Maxwell SRJ, Lip GYH. Reperfusion injury: a review of the pathophysiology, clinical manifestations and therapeutic options. Int J Cardiol. 1997; 58: 95-117
5. McCord JM. Oxygen-derived free radicals in post-ischaemic tissue injury. N Engl J Med. 1985; 312: 159-163.
6. Parratt JR, Wainwright CL. Failure of allopurinol and a spin trapping agent N-t-butyl-a-phenyl nitrone to modify significantly ischaemia and reperfusion-induced arrhythmias. Br J Pharmacol. 1987; 91: 49-59.
7. Healing G, Gower J, Fuller B, Green C. Intracellular iron redistribution. An important determinant of reperfusion damage to rabbit kidneys. Biochem Pharmacol. 1990; 39: 1239-1245.
8. Lab MJ. Contraction-excitation feedback in myocardium: physiological basis and clinical relevance. Circ Res. 1982; 50: 757-766
9. Dean JW, Lab MJ. Arrhythmia in heart failure: Role of mechanically induced changes in electrophysiology. Lancet. 1989; Suppl(I): 1309-1312.
10. Sideris DA, Toumanidis ST, Chrysos DN, Mertzanidis ET, Vardas PE, Moulopoulos SD. Effect of blood pressure changes on the cardiac rhythm. Hellenic J Cardiol. 1985; 26: 52-57. Greek.
11. Sideris DA, Chrysos DN, Maliaras GK, Michalis LK, Moulopoulos SD. Effect of acute hypertension on the cardiac rhythm. Experimental observations. J Electrocardiol. 1988; 21: 183-191.
12. Sideris DA, Kontoyannis DA, Michalis L, Adractas A, Moulopoulos SD. Acute changes in blood pressure as a cause of cardiac arrhythmias. Eur Heart J. 1987; 8: 45-52.
13. Sideris DA. High blood pressure and ventricular arrhythmias. Eur Heart J. 1993; 14: 1548-1553.
14. Shofti R, Zaretzki A, Cohen E, Engel A, Bar-EIY. The sheep as a model for coronary artery bypass surgery. Lab Anim. 2004; 38: 149-157.
15. Wang S, Dusting GJ, May CN, Woodman OL. 3′,4′- Dihydroxyflavonol reduces infarct size and injury associated with myocardial ischaemia and reperfusion in sheep. Br J Pharmacol. 2004; 142: 443-452.
16. Markovitz LJ, Savage EB, et al. Large animal model of left ventricular aneurysm. Ann Thorac Surg. 1989; 48: 838-845.
17. Maxwell MP, Hearse DJ, Yellon DM. Species variation in the coronary collateral circulation during regional myocardial ischaemia: a critical determinant of the rate of evolution and extent of myocardial infarction. Cardiovasc Res. 1987; 21: 737-746.
18. Bolli R, Patel BS, Zhu W-X, et al. The iron chelator desferrioxamine attenuates postischemic ventricular dysfunction. Am J Physiol. 1987; 253 (6 Pt 2): H1372-H1380.
19. Myers M. L, R. Bolli, RF Lekich, et al. Enhancement of recovery of myocardial function by oxygen free-radical scavengers after reversible regional ischaemia. Circulation. 1985; 72: 915-921.
20. Siogas K, Pappas S, Graekas G, Goudevenos J, Liapi G, Sideris DA. Segmental wall motion abnormalities alter vulnerability to ventricular ectopic beats associated with acute increases in aortic pressure in patients with underlying coronary artery disease. Heart. 1998; 79: 268-273.
21. Sideris DA. The importance of blood pressure in the emergence of arrhythmias. Eur Heart J. 1987; 8(Suppl D): 129-131.
22. Sideris DA, Toumanidis ST, Kostis EB, Diakos A, Moulopoulos SD. Arrhythmogenic effect of high blood pressure: Some observations on its mechanism. Cardiovasc Res. 1989; 23: 983-992.
23. Sideris DA, Toumanidis ST, Kosstis EV, Diakos A, Maliaras G, Moulopoulos SD. Blood pressure and ventricular arrhythmias. Significance of ventricular dilation. Hellenic J Cardiol. 1987; 28: 301-306. Greek.
24. Sideris DA, Toumanidis ST, Kostis EB, Spyropoulos G, Moulopoulos SD. Effect of adrenergic blockade on pressure-related ventricular arrhythmias. Acta Cardiol. 1991; 46: 215-225.
25. Sideris DA, Toumanidis ST, Anastasiou-Nana M, et al. The circadian profile of extrasystolic arrhythmia: its relationship to heart rate and blood pressure. Int J Cardiol. 1992; 34: 21-31.
26. Sideris DA, Kontoyannis DA, Anastasiou-Nana M, Diakos A, Moulopoulos SD. Effect of blood pressure on variations in ventricular ectopy. J Ambul Monit. 1990; 3: 119-127.
27. Rimm EB, Stampfer MJ, Ascherio A, et al. Vitamin E consumption and the risk of coronary heart disease in men. N Engl J Med. 1993; 328: 1450-1456.
28. Christen WG, Gaziano JM, Hennekens CH. Design of Physicians' Health Study II - a randomized trial of beta carotene, vitamins E and C, and multivitamins, in prevention of cancer, cardiovascular disease, and eye disease, and review of results of completed trials. Ann Epidemiol. 2000; 10: 125-134.
29. Riemersma RA, Carruthers KF, Elton RA, Fox KA. Vitamin C and the risk of acute myocardial infarction. Am J Clin Nutr. 2000; 71: 1181-1186.
30. Singh RB, Niaz MA, Rastogi SS, Rastogi S. Usefulness of antioxidant vitamins in suspected acute myocardial infarction (the Indian experiment of infarct survival-3). Am J Cardiol. 1996; 77: 232-236.
31. Salonen JT, Salonen R, Penttila I, et al. Serum fatty acids, apolipoproteins, selenium, vitamin antioxidants and the risk of death from coronary artery disease. Am J Cardiol. 1985; 56: 226-231.
32. Enstrom JE, Kanim LE, Klein MA. Vitamin C intake and mortality among a sample of the United States population. Epidemiol. 1992; 3: 194-202.
33. Hercberg S, Preziosi P, Galan P, et al. 'The SU. VI. MAX Study': a primary prevention trial using nutritional doses of antioxidant vitamins and minerals in cardiovascular diseases and cancers. Supplementation on Vitamines et Miniraux Antioxydants. Food Chem Toxicol. 1999; 37: 925-930.
34. Coetzee WA, Owen P, Dennis SC, Saman S, Opie LH. Reperfusion damage: free radicals mediate delayed membrane changes rather than early ventricular arrhythmias. Cardiovasc Res. 1990; 24: 156-164.
35. Hagar JM, Hale SL, Ilvento JP, Kloner RA. Lack of significant effects of superoxide dismutase and Catalase on development of reperfusion arrhythmias. Basic Res Cardiol. 1991; 86: 127-135.
36. Bolli R, Patel BS, Jeroudi MO, Lai EK, McCay PB. Demonstration of free radical generation in "stunned" myocardium of intact dogs with the use of the spin trap a-phenyl N-tertbutyl nitrone. J Clin Invest. 1988; 82: 476-485.
37. Bolli R, Zhu W-X, Hartley CJ, et al. Attenuation of dysfunction in the postischaemic "stunned" myocardium by dimethylthiourea. Circulation. 1987; 76: 458-468.
38. Farber NE, Vercelloti GM, Jacob HS, Pieper GM, Gross GJ. Evidence for a role of iron-catalyzed oxidants in functional and metabolic stunning in the canine heart. Circ Res. 1988; 63: 351-360.
39. Gross GJ, Farber NE, Hardman HF, Warltier DC. Beneficial actions of superoxide dismutase and Catalase in stunned myocardium of dogs. Am J Physiol. 1986; 250(Heart Circ Physiol 19): H372-H377.
40. Myers ML, Bolli R, Lekich RF, et al. N-2-mercaptopropionylglycine improves recovery of myocardial function after reversible regional ischaemia. J Am Coll Cardiol. 1986; 8: 1161-1168.
41. Przyklenk K, Kloner RA. Superoxide dismutase plus Catalase improve contractile function in the canine model of the "stunned myocardium". Circ Res. 1986; 58: 148-156.
42. Bolli R, Patel BS. Factors that determine the occurrence of reperfusion arrhythmias. Am Heart J. 1988; 115: 20-29.
43. Hearse DJ, Bolli R. Reperfusion induced injury: manifestations, mechanisms, and clinical relevance. Cardiovasc Res. 1992; 26: 101-108.
44. Bernier M, Manning AS, Hearse DJ. Reperfusion arrhythmias: dose-related protection by anti-free radical interventions. Am J Physiol. 1989; 256: H1344-1352.
45. Bernier M, Hearse DJ. Reperfusion-induced arrhythmias: mechanisms of protection by glucose and mannitol. Am J Physiol. 1988; 254: H862-870.
46. Riva E, Manning AS, Hearse DJ. Superoxide dismutase and the reduction of reperfusion-induced arrhythmias: in vivo dose-response studies in the rat. Cardiovasc Drug Ther. 1987; 1: 133-139.
47. Woodward B, Zakaria MNM. Effect of some free radical scavengers on reperfusion induced arrhythmias in the isolated rat heart. J Mol Cell Cardiol. 1985; 17: 485-493.
48. Nejima J, Knight DR, Fallon JT, et al. Superoxide dismutase reduces reperfusion arrhythmias but fails to salvage regional function or myocardium at risk in conscious dogs. Circulation. 1989; 79: 143-153.
49. Watanabe N, Inoue M, Morino Y. Inhibition of post ischaemic reperfusion arrhythmias by an SOD derivative that circulates bound to albumin with prolonged in vivo half life. Biochem Pharmacol. 1989; 79: 143-153.
50. Myers CL, Weiss SJ, et al. Involvement of hydrogen peroxide and hydroxyl radical in the "oxygen paradox": reduction of creatine kinase release by Catalase, allopurinol or deferoxamine but not by superide dismutase. J Mol Cell Cardiol. 1985; 17: 675-685.
51. Bolli R, Patel BS, Zhu WX, et al. The iron chelator desferioxamine attenuates postischaemic ventricular dysfunction. Am J Physiol. 1987; 253: H1372-H1380.
52. Calvert A, Lown B, Gorlin R. Ventricular premature beats and anatomically defined coronary heart disease. Am J Cardiol. 1977; 39: 627-634.
53. Califf RM, Burks JM, Behar VS, et al. Relationships among ventricular arrhythmias, coronary artery disease and angiographic and electrocardiographic indicators of myocardial fibrosis. Circulation. 1978; 57: 725-732.
54. Weaver WD, Lorch GS, et al. Angiographic findings and prognostic indicators in patients resuscitated from cardiac death. Circulation. 1976; 54: 895-900.
55. Schultz RA, Strauss HW, Pitt B. Sudden death in the year following myocardial infarction: relation to ventricular premature contractions in the late hospital phase and left ventricular function. Am J Med. 1977; 62: 192-199.
56. Kostis JB. The prognostic significance of ventricular ectopic activity. Am J Cardiol. 1992; 70: 807-808.
57. White HD, Norris RN, Brown MA, et al. Left ventricular end systolic volume as the major determinant of survival after recovery from myocardial infarction. Circulation. 1987; 76: 44-51.
58. Steinberg D, Parthasarathy S, Carew T. Beyond cholesterol-modifications of low-density lipoprotein that increase its atherogenicity. N Engl J Med. 1989; 320: 915-924.
59. Heineche W, Kawamura M, Suzuki L. Oxidation of low density lipoprotein by thiols: superoxide-dependent and-independent mechanisms. J Lipid Res. 1993; 34: 2051-2061.
60. Antoniades C, Tousoulis D, Marinou K, et al. Effects of lipid profile on forearm hyperaemic response in young subjects. Hellenic J Cardiol. 2006; 47:152-157.
61. Gryglewski RJ, Palmer RM, Moncada S. Superoxide anions involved in the breakdown of endothelium-derived vascular relaxing factor. Nature. 1986; 320: 454-456.
62. Solzbach U, Hornig B, Jeserich M, Just H. Vitamin C improves endothelial dysfunction of epicardial coronary arteries in hypertensive patients. Circulation. 1997; 96: 1513-1519.
63. Ohara Y, Peterson TE, Zheng B. Lysophosphatidylcholine increases vascular superoxide anion production via protein kinase C activation. Arterioscler Thromb Vasc Biol. 1998; 14: 1007-1013.
64. Timimi FK, Ting HH, Haley EA, et al. Vitamin C improves endothelium dependent vasodilation in patients with insulin-dependent diabetes mellitus. J Am Coll Cardiol. 1998; 31: 552-557.
65. Raitakari QT, Adams MR, McCredie RJ, et al. Oral vitamin C and endothelial function in smokers: short-term improvement but no sustained beneficial effect. J Am Coll Cardiol. 2000; 35: 1616-1620.
66. Levine GN, Frei B, Koulouris SN, et al. Ascorbic acid reverses endothelial dysfunction in patients with coronary artery disease. Circulation. 1996; 93: 1107-1113.
67. Gokce N, Keaney JF Jr, Frei B, et al. Long-term ascorbic acid administration reserves endothelial vasomotor dysfunction in patients with coronary artery disease. Circulation. 1999; 99: 3234-3240.
68. Solzbach U, Hornig B, Jeserich M, Just H. Vitamin C improves endothelial dysfunction of epicardial coronary arteries in hypertensive patients. Circulation. 1997; 96: 1513-1519.
69. Taddei S, Virdis A, Ghiadoni L, Magagna A. Salvetti A. Vitamin C improves endothelium-dependent vasodilation by restoring nitric oxide activity in essential hypertension. Circulation. 1998; 97: 2222-2229.