Influence of polymeric excipients on crystal hydrate formation kinetics in aqueous slurries

Journal of Pharmaceutical Sciences

Volumn 97, Issue 12, 2008, Pages 5198-5211

  Gift, Alan D ^a,b   Luner, Paul E ^c   Luedeman, Laura ^b   Taylor, Lynne S ^b  

^a INDIANA UNIVERSITY SOUTH BEND   (United States)

^b PURDUE UNIVERSITY   (United States)

^c PFIZER INC   (United States)

Author keywords

Crystal; Excipients; Hydrate; Induction; Inhibition; Nucleation; Polymers; Raman spectroscopy; Solution mediated transformation

Indexed keywords

CAFFEINE; CARBAMAZEPINE; EXCIPIENT; HYDROXYPROPYLMETHYLCELLULOSE; POLYACRYLIC ACID; POVIDONE; SULFAGUANIDINE;

AQUEOUS SOLUTION; ARTICLE; CRYSTAL; DRUG MANUFACTURE; DRUG TRANSFORMATION; HYDRATION; RAMAN SPECTROMETRY;

EID: 57349145338     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21379     Document Type: Article

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