Frequency of apolipoprotein E4 among older compared with younger HIV patients: Support for detrimental effect of E4 on survival

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 41, 2008, Pages

  Valcour, Victor ^a   Shiramizu, Bruce ^a   Shikuma, Cecilia ^a  

^a UNIVERSITY OF HAWAII   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E4; VIRUS DNA; VIRUS RNA;

ALLELE; CD4+ T LYMPHOCYTE; DEMENTIA; DISEASE FREE SURVIVAL; GENE FREQUENCY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; LETTER; LYMPHOCYTE COUNT; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL;

AGE FACTORS; APOLIPOPROTEIN E4; HIV INFECTIONS; HUMANS; SURVIVAL RATE;

EID: 57349135728     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0806919105     Document Type: Letter

References (3)

1. Burt TD, et al. (2008) Apolipoprotein (apo) E4 enhances HIV-1 cell entry in vitro, and the APOE ε4/ε4 genotype accelerates HIV disease progression. Proc Natl Acad Sci USA 105:8718-8723.
2. Valcour V, et al. (2004) Age, apolipoprotein E4, and the risk of HIV dementia: The Hawaii Aging with HIV Cohort. J Neuroimmunol 157:197-202.
3. Shiramizu B, et al. (2005) Circulating proviral HIV DNA and HIV-associated dementia. AIDS 19:45-52.