The utility of 6-month protocol renal biopsy under modern immunosuppression

Clinical Nephrology

Volumn 70, Issue 6, 2008, Pages 490-495

  Yango, A ^a   Gohh, R ^a   Wang, L J ^a   Morrissey, P ^a   Shih, M ^a   Lowery, K ^a   Charpentier, K ^a   Gautam, A ^a   Mendonca, C ^a   Kumar, S ^b   Dworkin, L ^a   Monaco, A ^a  

^a BROWN UNIVERSITY   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Chronic allograft; Nephropathy; Protocol biopsy; Renal transplantation; Subclinical rejection

Indexed keywords

CORTICOSTEROID; CREATINE; LYMPHOCYTE ANTIBODY; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; TACROLIMUS; THYMOCYTE ANTIBODY;

ABDOMINAL PAIN; ADULT; ARTICLE; CHRONIC ALLOGRAFT NEPHROPATHY; CLINICAL ARTICLE; CREATINE KINASE BLOOD LEVEL; DIARRHEA; DRUG DOSE REDUCTION; EARLY DIAGNOSIS; FEMALE; GASTROINTESTINAL SYMPTOM; GLOMERULUS FILTRATION RATE; GRAFT RECIPIENT; GRAFT SURVIVAL; HUMAN; HUMAN TISSUE; IMMUNOSUPPRESSIVE TREATMENT; INCIDENCE; KIDNEY ALLOGRAFT REJECTION; KIDNEY BIOPSY; KIDNEY FUNCTION; KIDNEY TRANSPLANTATION; LEUKOPENIA; MALE; NAUSEA; PROTEIN URINE LEVEL; VOMITING;

EID: 57349121649     PISSN: 03010430     EISSN: None     Source Type: Journal    
DOI: 10.5414/cnp70490     Document Type: Article

References (17)

1. Carpenter CB. Long-term failure of renal transplants: adding insult to injury. Kidney Int. 1995; 48: S40-S44.
2. Feucht HE, Schneeberger H, Hilebrand G et al. Capillary deposition ofC4d complement fragment and early renal graft loss. Kidney Int. 1993; 43: 1333-1338.
3. Gloor JM, Cohen AJ, Lager DJ et al. Subclinical rejection in tacrolimus-treated renal transplant recipients. Transplantation. 2002; 73: 1965-1968.
4. Gloor JM, Sethi S, Stegall MD, Park WD et al. Transplant glomerulopathy: subclinical incidence and association with alloantibody. Am J Transplant. 2007; 9: 2124-2132.
5. Isoniemi HM, Taskinen E, Hayry P. Histological chronic allograft damage index accurately predicts chronic renal allograft rejection. Transplantation. 1994; 58: 1195-1198.
6. Laftavi MR, Stephan RN, Stephanik BK et al. The significance of protocol biopsies in the modern immuno-suppressive era; what for? Am J Transplant. 2004; 4 (Suppl 8): 224.
7. Lipman ML, Lavery P, Shi Y et al. Incidence of subclinical rejection in protocol biopsies procured from renal transplant recipients on tacrolimus-based immunosuppressive regimen. Am J Transplant. 2004; 4 (Suppl 8): 551.
8. Nankivell BJ, Borrows RJ, Fung CL et al. The natural history of chronic allograft nephropathy. N Engl J Med. 2003; 24: 2326-2333.
9. Nankivell BJ, Borrows RJ, Fung CL et al. Natural history, risk factors, and impact of subclinical rejection in kidney transplantation. Transplantation. 2004; 78: 242-249.
10. Racusen LC, Solez K, Colvin RB et al. The Banff 97 working classification of renal allograft pathology. Kidney Int. 1999; 55: 713.
11. Rea DJ, Stegall MD, Cosio FG et al. Histologic findings on surveillance protocol biopsies after renal transplantation. Am J Transplant. 2004; 4: 566.
12. Regele H, Bohmig GA, Habicht A et al. Capillary deposition of complement split product C4d in renal allografts is associated with basement membrane injury in peritubular and glomerular capillaries: a contribution of humural immunity to chronic allograft rejection. J Am Soc Nephrol. 2002; 13: 2371-2380.
13. Rush D, Nickerson P, Gough J et al. The beneficial effects of treatment of early subclinical rejection: a randomized study. J Am Soc Nephrol. 1998; 9: 2129-2134.
14. Rush D, Nankivell BJ, Borrows R et al. Natural history, risk factors, and impact of subclinical rejection in kidney transplantation. Transplantation. 2004; 78: 242-249.
15. Sijpkens YW, Joosten SA, Paul LC. Chronic rejection in renal transplantation. Transplant Rev. 2003; 17: 118-130.
16. Solez K, Vincenti F, Filo RS. Histopathologic findings from 2-year protocol biopsies from a US multicenter kidney transplant center comparing tacrolimus vs cyclsoporine. Transplantation. 1998; 66: 1736-1740.
17. Tullius SG, Tilney NL. Both alloantigen-dependent and independent factors influence chronic allograft rejection. Transplantation. 1995; 59: 313-317.