Role of the Caenorhabditis elegans Shc adaptor protein in the c-Jun N-terminal kinase signaling pathway

Molecular and Cellular Biology

Volumn 28, Issue 23, 2008, Pages 7041-7049

  Mizuno, Tomoaki ^b   Fujiki, Kota ^b   Sasakawa, Aya ^b   Hisamoto, Naoki ^b   Matsumoto, Kunihiro ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ARSENIC TRIOXIDE; CAENORHABDITIS ELEGANS PROTEIN; HEAVY METAL; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MIXED LINEAGE KINASE; MIXED LINEAGE KINASE 1; PROTEIN SHC; PROTEIN SHC 1; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; ENZYME ACTIVATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BINDING SITES; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE KINASE 1; METALS, HEAVY; MUTATION; SHC SIGNALING ADAPTOR PROTEINS; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL;

CAENORHABDITIS ELEGANS;

EID: 57349117119     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.00938-08     Document Type: Article

References (32)

1. Brenner, S. 1974. The genetics of Caenorhabditis elegans. Genetics 77:71-94.
2. Byrd, D. T., M. Kawasaki, M. Walcoff, N. Hisamoto, K. Matsumoto, and Y. Jin. 2001. UNC-16, a JNK-signaling scaffold protein, regulates vesicle transport in C. elegans. Neuron 32:787-800.
3. Calfon, M., H. Zeng, F. Urano, J. H. Till, S. R. Hubbard, H. P. Harding, S. G. Clark, and D. Ron. 2002. IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA. Nature 415:92-96.
4. Chang, L., and M. Karin. 2001. Mammalian MAP kinase signalling cascades. Nature 410:37-40.
5. Dhanasekaran, D. N., K. Kashef, C. M. Lee, H. Xu, and E. P. Reddy. 2007. Scaffold proteins of MAP-kinase modules. Oncogene 26:3185-3202.
6. Eisenmann, D. M., and S. K. Kim. 1994. Signal transduction and cell fate specification during Caenorhabditis elegans vulval development. Curr. Opin. Genet. Dev. 4:508-516.
7. Han, M., A. Golden, Y. Han, and P. W. Sternberg. 1993. C. elegans lin-45 raf gene participates in let-60 ras-stimulated vulval differentiation. Nature 363:133-140.
8. Inoue, H., N. Hisamoto, J. H. An, R. P. Oliveira, E. Nishida, T. K. Blackwell, and K. Matsumoto. 2005. The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response. Genes Dev. 19:2278-2283.
9. Kawasaki, M., N. Hisamoto, Y. Iino, M. Yamamoto, J. Ninomiya-Tsuji, and K. Matsumoto. 1999. A Caenorhabditis elegans JNK signal transduction pathway regulates coordinated movement via type-D GABAergic motor neurons. EMBO J. 18:3604-3615.
10. Kim, D. H., R. Feinbaum, G. Alloing, F. E. Emerson, D. A. Garsin, H. Inoue, M. Tanaka-Hino, N. Hisamoto, K. Matsumoto, M. W. Tan, and F. M. Ausubel. 2002. A conserved p38 MAP kinase pathway in Caenorhabditis elegans innate immunity. Science 297:623-626.
11. Kim, D. H., N. T. Liberati, T. Mizuno, H. Inoue, N. Hisamoto, K. Matsumoto, and F. M. Ausubel. 2004. Integration of Caenorhabditis elegans MAPK pathways mediating immunity and stress resistance by MEK-1 MAPK kinase and VHP-1 MAPK phosphatase. Proc. Natl. Acad. Sci. 101:10990- 10994.
12. Kornfeld, K., K. L. Guan, and H. R. Horvitz. 1995. The Caenorhabditis elegans gene mek-2 is required for vulval induction and encodes a protein similar to the protein kinase MEK. Genes Dev. 9:756-768.
13. Kyriakis, J. M., and J. Avruch. 2001. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol. Rev. 81:807-869.
14. Lackner, M. R., K. Kornfeld, L. M. Miller, H. R. Horvitz, and S. K. Kim. 1994. A MAP kinase homolog, mpk-1, is involved in ras-mediated induction of vulval cell fates in Caenorhabditis elegans. Genes Dev. 8:160-173.
15. Laminet, A. A., G. Apell, L. Conroy, and W. M. Kavanaugh. 1996. Affinity, specificity, and kinetics of the interaction of the SHC phosphotyrosine binding domain with asparagine-X-X-phosphotyrosine motifs of growth factor receptors. J. Biol. Chem. 271:264-269.
16. Li, S., C. M. Armstrong, N. Bertin, H. Ge, S. Milstein, M. Boxem, P. O. Vidalain, J. D. Han, A. Chesneau, T. Hao, D. S. Goldberg, N. Li, M. Martinez, J. F. Rual, P. Lamesch, L. Xu, M. Tewari, S. L. Wong, L. V. Zhang, G. F. Berriz, L. Jacotot, P. Vaglio, J. Reboul, T. Hirozane-Kishikawa, Q. Li, H. W. Gabel, A. Elewa, B. Baumgartner, D. J. Rose, H. Yu, S. Bosak, R. Sequerra, A. Fraser, S. E. Mango, W. M. Saxton, S. Strome, S. Van Den Heuvel, F. Piano, J. Vandenhaute, C. Sardet, M. Gerstein, L. Doucette-Stamm, K. C. Gunsalus, J. W. Harper, M. E. Cusick, F. P. Roth, D. E. Hill, and M. Vidal. 2004. A map of the interactome network of the metazoan C. elegans. Science 303:540-543.
17. Luschnig, S., J. Krauss, K. Bohmann, I. Desjeux, and C. Nüsslein-Volhard. 2000. The Drosophila SHC adaptor protein is required for signaling by a subset of receptor tyrosine kinases. Mol. Cell 5:231-241.
18. Luzi, L., S. Confalonieri, P. P. Di Fiore, and P. G. Pelicci. 2000. Evolution of Shc functions from nematode to human. Curr. Opin. Genet. Dev. 10:668-674.
19. McKay, M. M., and D. K. Morrison. 2007. Integrating signals from RTKs to ERK/MAPK. Oncogene 26:3113-3121.
20. Mello, C. C., J. M. Kramer, D. Stinchcomb, and V. Ambros. 1991. Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences. EMBO J. 10:3959-3970.
21. Mizuno, T., N. Hisamoto, T. Terada, T. Kondo, M. Adachi, E. Nishida, D. H. Kim, F. M. Ausubel, and K. Matsumoto. 2004. The C. elegans MAPK phosphatase VHP-1 mediates a novel JNK-like signaling pathway in stress response. EMBO J. 23:2226-2234.
22. Morrison, D. K., and R. J. Davis. 2003. Regulation of MAP kinase signaling modules by scaffold proteins in mammals. Annu. Rev. Cell Dev. Biol. 19:91-118.
23. Pawson, T., and J. D. Scott. 1997. Signaling through scaffold, anchoring, and adaptor proteins. Science 278:2075-2080.
24. Ravichandran, K. S. 2001. Signaling via Shc family adapter proteins. Oncogene 20:6322-6330.
25. Schlessinger, J. 2000. Cell signaling by receptor tyrosine kinases. Cell 103:211-225.
26. Smith, P., W. M. Leung-Chiu, R. Montgomery, A. Orsborn, K. Kuznicki, E. Gressman-Coberly, L. Mutapcic, and K. Bennett. 2002. The GLH proteins, Caenorhabditis elegans P granule components, associate with CSN-5 and KGB-1, proteins necessary for fertility, and with ZYX-1, a predicted cytoskeletal protein. Dev. Biol. 251:333-347.
27. Sundaram, M. V. 11 February 2006. RTK/Ras/MAPK signaling. In The C. elegans Research Community, WormBook (ed.), WormBook. doi/10.1895/wormbook.1.80.1. http://www.wormbook.org.
28. Uhlik, M. T., B. Temple, S. Bencharit, A. J. Kimple, D. P. Siderovski, and G. L. Johnson. 2005. Structural and evolutionary division of phosphotyrosine binding (PTB) domains. J. Mol. Biol. 345:1-20.
29. van der Geer, P., S. Wiley, G. D. Gish, V. K. Lai, R. Stephens, M. F. White, D. Kaplan, and T. Pawson. 1996. Identification of residues that control specific binding of the Shc phosphotyrosine-binding domain to phosphotyrosine sites. Proc. Natl. Acad. Sci. 93:963-968.
30. Whitmarsh, A. J. 2006. The JIP family of MAPK scaffold proteins. Biochem. Soc. Trans. 34:828-832.
31. Wu, Y., and M. Han. 1994. Suppression of activated Let-60 Ras protein defines a role of Caenorhabditis elegans Sur-1 MAP kinase in vulval differentiation. Genes Dev. 8:147-159.
32. Wu, Y., M. Han, and K. L. Guan. 1995. MEK-2, a Caenorhabditis elegans MAP kinase kinase, functions in Ras-mediated vulval induction and other developmental events. Genes Dev. 9:742-755.