Interactions of mineralocorticoids and glucocorticoids in epithelial target tissues revisited

Steroids

Volumn 74, Issue 1, 2009, Pages 1-6

  Morris, David J ^a   Latif, Syed A ^a   Brem, Andrew S ^a  

^a BROWN UNIVERSITY   (United States)

Author keywords

11 HSD2; Glucocorticoids; Kidney; Mineralocorticoids; Sodium transport

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE 2; ALDOSTERONE; CORTICOSTERONE; DEHYDROCORTICOSTERONE; GLUCOCORTICOID; MINERALOCORTICOID; MINERALOCORTICOID RECEPTOR; POTASSIUM ION; SODIUM ION;

EPITHELIUM; HORMONE BINDING; HUMAN; MOLECULAR INTERACTION; NONHUMAN; RECEPTOR BINDING; REVIEW; SODIUM RETENTION; SODIUM TRANSPORT;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2; ANIMALS; EPITHELIUM; GLUCOCORTICOIDS; HUMANS; ION TRANSPORT; MINERALOCORTICOIDS; RECEPTORS, GLUCOCORTICOID; RECEPTORS, MINERALOCORTICOID; SODIUM;

ANIMALIA;

EID: 57249113695     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2008.10.005     Document Type: Review

References (43)

1. Mercer W.R., and Krozowski Z.S. Localization of an 11 beta hydroxysteroid dehydrogenase activity to the distal nephron. Evidence for the existence of two species of dehydrogenase in the rat kidney. Endocrinology 130 (1992) 540-543
2. Rusvai E., and Naray-Fejes-Toth A. A new isoform of 11 beta-hydroxysteroid dehydrogenase in aldosterone target cells. J Biol Chem 268 (1993) 10717-10720
3. Walker B.R., Campbell J.C., Williams B.C., and Edwards C.R. Tissue-specific distribution of the NAD(+)-dependent isoform of 11 beta-hydroxysteroid dehydrogenase. Endocrinology 131 (1992) 970-972
4. Brem A.S., Matheson K.L., Conca T., and Morris D.J. Effect of carbenoxolone on glucocorticoid metabolism and Na transport in toad bladder. Am J Physiol 257 (1989) F700-F704
5. Gaeggeler H.P., Edwards C.R., and Rossier B.C. Steroid metabolism determines mineralocorticoid specificity in the toad bladder. Am J Physiol 257 (1989) F690-F695
6. Naray-Fejes-Toth A., Rusvai E., and Fejes-Toth G. Mineralocorticoid receptors and 11 beta-steroid dehydrogenase activity in renal principal and intercalated cells. Am J Physiol 266 (1994) F76-80
7. Stewart P.M., Whorwood C.B., and Walker B.R. Steroid hormones and hypertension: the cortisol-cortisone shuttle. Steroids 58 (1993) 614-620
8. Barger A.C., Berlin R.D., and Tulenko J.F. Infusion of aldosterone, 9-alpha-fluorohydrocortisone, and antidiuretic hormone into the renal artery of normal and adrenalectomized unanesthetized dogs: effect on electrolyte and water excretion. Endocrinology 62 (1958) 804-815
9. Morris D.J., Berek J.S., and Davis R.P. The physiological response to aldosterone in adrenalectomized and intact rats and its sex dependence. Endocrinology 92 (1973) 989-993
10. Ross E.J. Modification of the effects of aldosterone on electrolyte excretion in man by simultaneous administration of corticosterone and hydrocortisone. Relevance to Conn's syndrome. J Clin Endocrinol Metab 20 (1960) 229-237
11. Selye H. Anticortisol action of aldosterone. Science 121 (1955) 368-369
12. Uete T., and Venning E.H. The effect of cortisone, hydrocortisone, and 9-alpha-fluoro-16-alpha-hydroxy-delta-hydrocortisone on the action of desoxycorticosterone and aldosterone with respect to electrolyte excretion. Endocrinology 67 (1960) 62-69
13. Alberti K.G.M.M., and Sharp G.W.G. Identification of four types of steroid by their interaction with mineralocorticoid receptors in the toad bladder. J Endocrinol 48 (1970) 563-574
14. Brem A.S., Matheson K.L., Latif S., and Morris D.J. Activity of 11 beta-hydroxysteroid dehydrogenase in toad bladder: effects of 11-dehydrocorticosterone. Am J Physiol 264 (1993) F854-F858
15. Brem A.S., Matheson K.L., Barnes J.L., and Morris D.J. 11-Dehydrocorticosterone, a glucocorticoid metabolite, inhibits aldosterone action in toad bladder. Am J Physiol 261 (1991) F873-F879
16. Kenyon C.J., Saccoccio N.A., and Morris D.J. Glucocorticoid inhibition of mineralocorticoid action in the rat. Clin Sci (Lond) 67 (1984) 329-335
17. Souness G.W., Myles K., and Morris D.J. Other physiological considerations of protective mechanisms of mineralocorticoid action. Steroids 59 (1994) 142-147
18. Morris D.J., Souness G.W., Brem A.S., and Oblin M.E. Interactions of mineralocorticoids and glucocorticoids in epithelial target tissues. Kidney Int 57 (2000) 1370-1373
19. Mader I.J., and Iseri L.T. Spontaneous hypopotassiumia, hypomagnesemia, alkalosis and tetany due to hypersecretion of corticosterone-like mineralocorticoid. Am J Med 19 (1955) 976-988
20. + transport across rat inner medullary collecting duct by glucocorticoid and by mineralocorticoid hormones. J Clin Invest 86 (1990) 498-506
21. Naray-Fejes-Toth A., and Fejes-Toth G. Glucocorticoid receptors mediate mineralocorticoid-like effects in cultured collecting duct cells. Am J Physiol 259 (1990) F672-F678
22. + transport in A6 cells is mediated via glucocorticoid receptors. Am J Physiol 264 (1993) C875-C884
23. Souness G.W., and Morris D.J. The "mineralocorticoid-like" actions conferred on corticosterone by carbenoxolone are inhibited by the mineralocorticoid receptor (type I) antagonist RU28318. Endocrinology 129 (1991) 2451-2456
24. Funder J., and Myles K. Exclusion of corticosterone from epithelial mineralocorticoid receptors is insufficient for selectivity of aldosterone action: in vivo binding studies. Endocrinology 137 (1996) 5264-5268
25. Funder J.W. Is aldosterone bad for the heart?. Trends Endocrinol Metab 15 (2004) 139-142
26. Sheppard K., and Funder J.W. Mineralocorticoid specificity of renal type I receptors: in vivo binding studies. Am J Physiol 252 (1987) E224-E229
27. + retention and hypertension. Endocr Res 22 (1996) 793-801
28. Morris D.J., Latif S.A., Hardy M.P., and Brem A.S. Endogenous inhibitors (GALFs) of 11β-OH-steroid dehydrogenase isoforms 1 and 2; derivatives of adrenally produced corticosterone and cortisol. J Steroid Biochem Mol Biol 104 (2007) 161-168
29. Lombes M., Binart N., Delahaye F., Baulieu E.E., and Rafestin-Oblin M.E. Differential intracellular localization of human mineralocorticosteroid receptor on binding of agonists and antagonists. Biochemistry 302 (1994) 191-197
30. Lombes M., Kenouch S., Souque E., Farman E.N., and Rafestin-Oblin M.E. The mineralocorticoid receptor discriminates aldosterone from glucocorticoids independently of the 11 beta-hydroxysteroid dehydrogenase. Endocrinology 135 (1994) 834-840
31. + transport by aldosterone. Am J Physiol 248 (1985) C102-C108
32. + permeability of toad urinary bladder. Am J Physiol 266 (1994) F108-F116
33. Gaeggeler H.P., Gonzalez-Rodriguez E., Jaeger N.F., Loffing-Cueni D., Norregaard R., Loffing J., et al. Mineralocorticoid versus glucocorticoid receptor occupancy mediating aldosterone-stimulated sodium transport in a novel renal cell line. J Am Soc Nephrol 16 (2005) 878-891
34. Arriza J.L., Weinberger C., Cerelli G., Glaser T.M., Handelin B.L., Housman D.E., et al. Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor. Science 237 (1987) 268-275
35. Edwards C.R., Stewart P.M., Burt D., Brett L., McIntyre M.A., Sutanto W.S., et al. Localisation of 11 beta-hydroxysteroid dehydrogenase-tissue specific protector of the mineralocorticoid receptor. Lancet 2 (1988) 986-989
36. Funder J.W., Pearce P.T., Smith R., and Smith A.I. Mineralocorticoid action: target tissue specificity is enzyme, not receptor mediated. Science 242 (1988) 583-585
37. Gong R., Morris D.J., and Brem A.S. Human renal 11beta-hydroxysteroid dehydrogenase 1 functions and co-localizes with COX-2. Life Sci 82 (2008) 631-637
38. Brem A.S., Bina R.B., and Ingelfinger J.R. Glucocorticoids mediate angiotensin II induced electrolyte transport in immortalized renal proximal tubule cells (IRPTC). Pediatr Res 39 (1996) 358A
39. Brem A.S., Bina R.B., King T., Chobanian M.C., and Morris D.J. Influence of dietary sodium on the renal isoforms of 11 beta-hydroxysteroid dehydrogenase. Proc Soc Exp Biol Med 214 (1997) 340-345
40. + channel in vitro and in vivo. Proc Natl Acad Sci U.S.A. 104 (2007) 4020-4024
41. + homeostasis. Proc Natl Acad Sci U.S.A. 104 (2007) 4025-4029
42. Odermatt A., Arnold P., and Frey. F.J. The intracellular localization of the mineralocorticoid receptor is regulated by 11beta-hydroxysteroid dehydrogenase type 2. J Biol Chem 276 (2001) 28484-28492
43. Funder J.W. Translational research goes both ways: lessons from clinical studies. Clin Exp Pharm Physiol 35 (2008) 526-529