Experimental study of cell migration and functional differentiation of transplanted neural stem cells co-labeled with superparamagnetic iron oxide and Brdu in an ischemic rat model

Biomedical and Environmental Sciences

Volumn 21, Issue 5, 2008, Pages 420-424

  Zhu, Wen Zhen ^a   Li, Xiang ^a   Qi, Jian Pin ^a   Tang, Zhou Ping ^a   Wang, Wei ^a   Wei, Li ^b   Lei, Hao ^b  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b Wuhan National Laboratory for Optoelectronics   (China)

Author keywords

Cell differentiation; Cell migration; Magnetic resonance imaging; Staining and labelling; Stem cell transplantation

Indexed keywords

RATTUS;

EID: 57249105538     PISSN: 08953988     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0895-3988(08)60063-X     Document Type: Article

References (7)

1. McKay R (2000). Stem cells: hype and hope. Nature 406, 361-364.
2. Gage F H (2000). Mammalian neural stem cell. Science 287(5457), 1433-1438.
3. Zhu W Z, Li X, Qi J P, et al. (2006). MRI tracking in vivo and in vitro of neural stem cells labeled with superparamagnetic iron oxide. J Chin Radiol 40(2), 160-164. (in Chinese)
4. Ittrich H, Lange C, Dahnke H et al. (2005). Labeling of mesenchymal stem cells with different superparamagnetic particles of iron oxide and detectability with MRI at 3T. Rofo 177(8), 1151-1163.
5. Magnitsky S, Watson D J, Walton R M, et al. (2005). In vivo and ex vivo MRI detection of localized and disseminated neural stem cell grafts in the mouse brain. Neuroimage 26(3), 744-754.
6. Jendelova P, Herynek V, DeCroos J, et al. (2003). Imaging the fate of implanted bone marrow stromal cells labelled with superparamagnetic nanoparticles. Magn Reson Med 50(4), 767-776.
7. Hoehn M, Kustermann E, Blank J, et al. (2002). Monitoring of implanted stem cell migration in vivo: a highly resolved in vivo magnetic resonance imaging investigation of experimental stroke in rat. Proc Natl Acad Sci USA 99(25), 16267-16272.