Imaging blood-brain barrier disruption: An evolving tool for assessing the risk of hemorrhage after thrombolysis: Commentary

Nature Clinical Practice Neurology

Volumn 4, Issue 12, 2008, Pages 644-645

  Tanne, David ^a  

^a SHEBA MEDICAL CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ALTEPLASE;

BLOOD BRAIN BARRIER; BLOOD CLOT LYSIS; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; CEREBROVASCULAR ACCIDENT; CONTRAST ENHANCEMENT; HIGH RISK PATIENT; HUMAN; IMAGE ANALYSIS; IMAGE DISPLAY; MEMBRANE DAMAGE; NOTE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR;

EID: 57249097128     PISSN: 1745834X     EISSN: 17458358     Source Type: Journal    
DOI: 10.1038/ncpneuro0935     Document Type: Note

References (8)

1. Saver JL (2004) Number needed to treat estimates incorporating effects over the entire range of clinical outcomes: Novel derivation method and application to thrombolytic therapy for acute stroke. Arch Neurol 61: 1066-1070
2. Tanne D et al. (2002) Markers of increased risk of intracerebral hemorrhage after intravenous recombinant tissue plasminogen activator therapy for acute ischemic stroke in clinical practice: The Multicenter rt-PA Stroke Survey. Circulation 105: 1679-1685
3. Sood RR et al. (2008) Early beneficial effect of matrix metalloproteinase inhibition on blood-brain barrier permeability as measured by magnetic resonance imaging countered by impaired long-term recovery after stroke in rat brain. J Cereb Blood Flow Metab 28 431-438
4. Su EJ et al. (2008) Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke. Nat Med 14:731-737
5. Singer OC et al. (2008) Risk for symptomatic intracerebral hemorrhage after thrombolysis assessed by diffusion-weighted magnetic resonance imaging. Ann Neurol 63: 52-60
6. Latour LL et al. (2004) Early blood-brain barrier disruption in human focal brain ischemia. Ann Neurol 56: 468-477
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8. Bang OY et al. (2007) Prediction of hemorrhagic transformation after recanalization therapy using T2*-permeability magnetic resonance imaging. Ann Neurol 62: 170-176