Synthesis and evaluation of some steroidal oximes as cytotoxic agents: Structure/activity studies (I)

Steroids

Volumn 74, Issue 1, 2009, Pages 62-72

  Cui, Jian Guo ^a   Fan, Lei ^a   Huang, Li Liang ^a   Liu, Hong Li ^b   Zhou, Ai Min ^b  

^a GUANGXI TEACHERS EDUCATION UNIVERSITY   (China)

^b CLEVELAND STATE UNIVERSITY   (United States)

Author keywords

Antiproliferative activity; Cytotoxicity; Steroidal oximes; Synthesis

Indexed keywords

ACETONE; CHOLESTEROL; CYTOTOXIC AGENT; DIHYDROXIMINO 24 ETHYLCHOLEST 4 EN; DIHYDROXIMINO 24 ETHYLCHOLEST 4,22 DIEN; DIHYDROXIMINOCHOLEST 4 ENE; HYDROXIMINO 24 ETHYLCHOLEST 4 EN; HYDROXIMINO 24 ETHYLCHOLEST 4 EN 6 ONE; HYDROXIMINO 24 ETHYLCHOLEST 4,22 DIEN; HYDROXIMINO 24 ETHYLCHOLEST 4,22 DIEN 6 ONE; HYDROXIMINO 24 ETHYLCHOLEST 5,22 DIEN 3 OL; HYDROXIMINO 24 ETHYLCHOLEST 5,22 DIEN 3 OL ACETATE; HYDROXIMINOCHOLEST 4 EN; HYDROXIMINOCHOLEST 4 EN 6ALPHA OL; HYDROXIMINOCHOLEST 5 EN 3 OL; HYDROXIMINOCHOLEST 5 EN 3 OL ACETATE; OXIME DERIVATIVE; SITOSTEROL; STEROID; STIGMASTEROL; UNCLASSIFIED DRUG;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; STRUCTURE ACTIVITY RELATION;

CELL LINE, TUMOR; CYTOTOXINS; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; OXIMES; STEROIDS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 57249094264     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2008.09.003     Document Type: Article

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