Activation of Tumor-Infiltrating Antigen Presenting Cells by High Intensity Focused Ultrasound Ablation of Human Breast Cancer

Ultrasound in Medicine and Biology

Volumn 35, Issue 1, 2009, Pages 50-57

  Xu, Zhong Lin ^a   Zhu, Xue Qiang ^a   Lu, Pei ^a   Zhou, Qiang ^a   Zhang, Jun ^a   Wu, Feng ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Antigen presenting cell; Antitumor immunity; Breast cancer; Dendritic cell; High intensity focused ultrasound; Thermal ablation

Indexed keywords

ABLATION; ACOUSTIC WAVES; ANTIGENS; DEBRIS; DENDRIMERS; INFILTRATION; MACROPHAGES; SOIL MECHANICS; TUMORS; ULTRASONIC TESTING; ULTRASONICS;

ANTITUMOR IMMUNITY; BREAST CANCER; DENDRITIC CELL; HIGH-INTENSITY FOCUSED ULTRASOUND; THERMAL ABLATION;

SONOCHEMISTRY;

B7 ANTIGEN; CD68 ANTIGEN; CD86 ANTIGEN; HLA DR ANTIGEN; PROTEIN S 100;

ADULT; ANTIGEN PRESENTING CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; B LYMPHOCYTE; BREAST CANCER; CANCER STAGING; CELL ACTIVATION; CELL INFILTRATION; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROL GROUP; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DENDRITIC CELL; DOUBLE BLIND PROCEDURE; ELECTROSURGERY; FEMALE; HIGH INTENSITY FOCUSED ULTRASOUND; HUMAN; IMMUNOHISTOCHEMISTRY; INFORMED CONSENT; MACROPHAGE; MASTECTOMY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TUMOR BIOPSY; TUMOR INFILTRATING ANTIGEN PRESENTING CELL;

ADULT; ANTIGEN-PRESENTING CELLS; ANTIGENS, CD; ANTIGENS, CD80; ANTIGENS, CD86; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; B-LYMPHOCYTES; BIOLOGICAL MARKERS; BREAST NEOPLASMS; FEMALE; HLA-DR ANTIGENS; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHOCYTE ACTIVATION; LYMPHOCYTES, TUMOR-INFILTRATING; MACROPHAGES; MASTECTOMY; MIDDLE AGED; S100 PROTEINS; ULTRASONIC THERAPY;

EID: 57249094252     PISSN: 03015629     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ultrasmedbio.2008.08.005     Document Type: Article

References (33)

1. Ali M.Y., Grimm C.F., Ritter M., Mohr L., Allgaier H.P., Weth R., Bocher W.O., Endrulat K., Blum H.E., and Geissler M. Activation of dendritic cells by local ablation of hepatocellular carcinoma. J Hepatol 43 (2005) 817-822
2. Allan C.P., Turtle C.J., Mainwaring P.N., Pyke C., and Hart D.N. The immune response to breast cancer, and the case for DC immunotherapy. Cytotherapy 6 (2004) 154-163
3. Bell D., Chomarat P., Broyles D., Netto G., Harb G.M., Lebecque S., Valladeau J., Davoust J., Palucka K.A., and Banchereau J. In breast carcinoma tissue, immature dendritic cells reside within the tumor, whereas mature dendritic cells are located in peritumoral areas. J Exp Med 190 (1999) 1417-1426
4. Chaussy C., Thuroff S., Rebillard X., and Gelet A. Technology insight: High-intensity focused ultrasound for urologic cancers. Nat Clin Pract Urol 2 (2005) 191-198
5. Coventry B.J., Lee P.L., Gibbs D., and Hart D.N. Dendritic cell density and activation status in human breast cancer-CD1a, CMRF- 44, CMRF-56 and CD-83 expression. Br J Cancer 86 (2002) 546-551
6. Enk A.H., Jonuleit H., Saloga J., and Knop J. Dendritic cells as mediators of tumor-induced tolerance in metastatic melanoma. Int J Cancer 73 (1997) 309-316
7. Gabrilovich D.I., Corak J., Ciernik I.F., Kavanaugh D., and Carbone D.P. Decreased antigen presentation by dendritic cells in patients with breast cancer. Clin Cancer Res 3 (1997) 483-490
8. Hu Z., Yang X.Y., Liu Y., Morse M.A., Lyerly H.K., Clay T.M., and Zhong P. Release of endogenous danger signals from HIFU-treated tumor cells and their stimulatory effects on APCs. Biochem Biophys Res Commun 335 (2005) 124-131
9. Illing R.O., Kennedy J.E., Wu F., ter Haar G.R., Protheroe A.S., Friend P.J., Gleeson F.V., Cranston D.W., Phillips R.R., and Middleton M.R. The safety and feasibility of extracorporeal high intensity focused ultrasound (HIFU) for the treatment of liver and kidney tumours in a Western population. Br J Cancer 93 (2005) 890-895
10. Kennedy J.E. High-intensity focused ultrasound in the treatment of solid tumours. Nat Rev Cancer 5 (2005) 321-327
11. Kramer G., Steiner G.E., Grobl M., Hrachowitz K., Reithmayr F., Paucz L., Newman M., Madersbacher S., Gruber D., Susani M., and Marberger M. Response to sublethal heat treatment of prostatic tumor cells and of prostatic tumor infiltrating T-cells. Prostate 58 (2004) 109-120
12. Lespagnard L., Gancberg D., Rouas G., Leclercq G., de Saint-Aubain Somerhausen N., Di Leo A., Piccart M., Verhest A., and Larsimont D. Tumor-infiltrating dendritic cells in neoplasms with a correlation to usual prognostic factors and to clinical outcome. Int J Cancer 84 (1999) 309-314
13. Lewko B., Zoltowska A., Stepinski J., Roszkiewicz A., and Moszkowska G. Dendritic and cancer cells in the breast tumors-An immunohistochemical study: Short communication. Med Sci Monit 6 (2000) 892-895
14. Lutz M.B., and Schuler G. Immature, semi-mature and fully mature dendritic cells: Which signals induce tolerance or immunity?. Trends Immunol 23 (2002) 445-449
15. Madersbacher S., Grobl M., Kramer G., Dirnhofer S., Steiner G.E., and Marberger M. Regulation of heat shock protein 27 expression of prostatic cells in response to heat treatment. Prostate 37 (1998) 174-181
16. Pinzon-Charry A., Maxwell T., and Lopez J.A. Dendritic cell dysfunction in cancer: A mechanism for immunosuppression. Immunol Cell Biol 83 (2005) 451-461
17. Pockley A.G. Heat shock proteins as regulators of the immune response. Lancet 362 (2003) 469-476
18. Rosberger D.F., Coleman D.J., Silverman R., Woods S., Rondeau M., and Cunningham-Rundles S. Immunomodulation in choroidal melanoma: Reversal of inverted CD4/CD8 ratios following treatment with ultrasonic hyperthermia. Biotechnol Ther 5 (1994) 59-68
19. Satthaporn S., Robins A., Vassanasiri W., El-Sheemy M., Jibril J.A., Clark D., Valerio D., and Eremin O. Dendritic cells are dysfunctional in patients with operable breast cancer. Cancer Immunol Immunother 53 (2004) 510-518
20. Scarpino S., Stoppacciaro A., Ballerini F., Marchesi M., Prat M., Stella M.C., Sozzani S., Allavena P., Mantovani A., and Ruco L.P. Papillary carcinoma of the thyroid: Hepatocyte Growth Factor (HGF) stimulates tumor cells to release chemokines active in recruiting dendritic cells. Am J Pathol 156 (2000) 831-837
21. Treilleux I., Blay J.Y., Bendriss-Vermare N., Ray-Coquard I., Bachelot T., Guastalla J.P., Bremond A., Goddard S., Pin J.J., Barthelemy-Dubois C., and Lebecque S. Dendritic cell infiltration and prognosis of early stage breast cancer. Clin Cancer Res 10 (2004) 7466-7474
22. Tsujitani S., Kakeji Y., Watanabe A., Kohnoe S., Maehara Y., and Sugimachi K. Infiltration of dendritic cells in relation to tumor invasion and lymph node metastasis in human gastric cancer. Cancer 66 (1990) 2012-2016
23. Vicari A.P., Caux C., and Trinchieri G. Tumour escape from immune surveillance through dendritic cell inactivation. Semin Cancer Biol 12 (2002) 33-42
24. Wang X., and Sun J. High-intensity focused ultrasound in patients with late-stage pancreatic carcinoma. Chin Med J (Engl) 115 (2002) 1332-1335
25. Wu F., Wang Z.B., Cao Y.D., Chen W.Z., Bai J., Zou J.Z., and Zhu H. A randomised clinical trial of high-intensity focused ultrasound ablation for the treatment of patients with localised breast cancer. Br J Cancer 89 (2003) 2227-2233
26. Wu F., Wang Z.B., Lu P., Xu Z.L., Chen W.Z., Zhu H., and Jin C.B. Activated anti-tumor immunity in cancer patients after high intensity focused ultrasound ablation. Ultrasound Med Biol 30 (2004) 1217-1222
27. Wu F. Extracorporeal high intensity focused ultrasound in the treatment of patients with solid malignancy. Minim Invasive Ther Allied Technol 15 (2006) 26-35
28. Wu F., Zhou L., and Chen W.R. Host antitumor immune responses to HIFU ablation. Int J Hyperthermia 23 (2007) 165-171
29. Wu F., Wang Z.B., Cao Y.D., Zhou Q., Zhang Y., Xu Z.L., and Zhu X.Q. Expression of tumor antigens and heat shock protein 70 in breast cancer cells after high intensity focused ultrasound ablation. Ann Surg Oncol 14 (2007) 1237-1242
30. Yang L., and Carbone D.P. Tumor-host immune interactions and dendritic cell dysfunction. Adv Cancer Res 92 (2004) 13-27
31. Yang R., Reilly C.R., Rescorla F.J., Sanghvi N.T., Fry F.J., Franklin Jr. T.D., and Grosfeld J.L. Effects of high-intensity focused ultrasound in the treatment of experimental neuroblastoma. J Pediatr Surg 27 (1992) 246-251
32. Zeid N.A., and Muller H.K. S100 positive dendritic cells in human lung tumors associated with cell differentiation and enhanced survival. Pathology 25 (1993) 338-343
33. Zhou Q., Zhu X.Q., Zhang J., Xu Z.L., Lu P., and Wu F. Changes in circulating immunosuppressive cytokine levels of cancer patients after high intensity focused ultrasound treatment. Ultrasound Med Biol 34 (2008) 81-87