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Volumn 69, Issue 12, 2008, Pages 815-825

Vaccinia virus-specific CD8+ T-cell responses target a group of epitopes without a strong immunodominance hierarchy in humans

Author keywords

CD8+ T cell epitope; HLA supertype; Immunodominance; Poxvirus; Vaccinia virus

Indexed keywords

EPITOPE; HLA A1 ANTIGEN; HLA A2 ANTIGEN; HLA A24 ANTIGEN; HLA A3 ANTIGEN; HLA B44 ANTIGEN; HLA B7 ANTIGEN; SMALLPOX VACCINE; VACCINIA VACCINE;

EID: 57149139113     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2008.09.009     Document Type: Article
Times cited : (25)

References (57)
  • 2
    • 0001459947 scopus 로고    scopus 로고
    • Poxviruses
    • Knipe D.M., and Howley P.M. (Eds), Lippincott Wiliams & Wilkins, Philadelphia
    • Esposito J.J., and Fenner F. Poxviruses. In: Knipe D.M., and Howley P.M. (Eds). Fields virology, vol 2 (2001), Lippincott Wiliams & Wilkins, Philadelphia 2885-2921
    • (2001) Fields virology, vol 2 , pp. 2885-2921
    • Esposito, J.J.1    Fenner, F.2
  • 4
    • 0019089482 scopus 로고
    • Acceptance of the Howland Award
    • Kempe C.H. Acceptance of the Howland Award. Pediatr Res 14 (1980) 1155-1161
    • (1980) Pediatr Res , vol.14 , pp. 1155-1161
    • Kempe, C.H.1
  • 5
    • 0015310485 scopus 로고
    • Vaccinia necrosum and its relationship to impaired immunologic responsiveness
    • Freed E.R., Duma R.J., and Escobar M.R. Vaccinia necrosum and its relationship to impaired immunologic responsiveness. Am J Med 52 (1972) 411-420
    • (1972) Am J Med , vol.52 , pp. 411-420
    • Freed, E.R.1    Duma, R.J.2    Escobar, M.R.3
  • 6
    • 0013904422 scopus 로고
    • Vaccinia gangrenosa with normal humora antibodies. A case possibly due to deficient cellular immunity treated with N-methylisatin β-thiosemicarbazone (compound 33T57, Marboran)
    • Hansson O., Johansson S.G.O., and Vahlquist B. Vaccinia gangrenosa with normal humora antibodies. A case possibly due to deficient cellular immunity treated with N-methylisatin β-thiosemicarbazone (compound 33T57, Marboran). Acta Paediatr Scand 55 (1966) 264-272
    • (1966) Acta Paediatr Scand , vol.55 , pp. 264-272
    • Hansson, O.1    Johansson, S.G.O.2    Vahlquist, B.3
  • 7
    • 0033538314 scopus 로고    scopus 로고
    • Smallpox as a biological weapon: medical and public health management. Working Group on Civilian Biodefense
    • Henderson D.A., Inglesby T.V., Bartlett J.G., Ascher M.S., Eitzen E., Jahrling P.B., et al. Smallpox as a biological weapon: medical and public health management. Working Group on Civilian Biodefense. J Am Med Assoc 281 (1999) 2127-2137
    • (1999) J Am Med Assoc , vol.281 , pp. 2127-2137
    • Henderson, D.A.1    Inglesby, T.V.2    Bartlett, J.G.3    Ascher, M.S.4    Eitzen, E.5    Jahrling, P.B.6
  • 9
    • 0030696246 scopus 로고    scopus 로고
    • Poxviruses as expression vectors
    • Carroll M.W., and Moss B. Poxviruses as expression vectors. Curr Opin Biotechnol 8 (1997) 573-577
    • (1997) Curr Opin Biotechnol , vol.8 , pp. 573-577
    • Carroll, M.W.1    Moss, B.2
  • 10
    • 12844261567 scopus 로고    scopus 로고
    • Fighting cancer with vaccinia virus: teaching new tricks to an old dog
    • Shen Y., and Nemunaitis J. Fighting cancer with vaccinia virus: teaching new tricks to an old dog. Mol Ther 11 (2005) 180-195
    • (2005) Mol Ther , vol.11 , pp. 180-195
    • Shen, Y.1    Nemunaitis, J.2
  • 11
    • 0037422549 scopus 로고    scopus 로고
    • Identification of vaccinia virus epitope-specific HLA-A*0201-restricted T cells and comparative analysis of smallpox vaccines
    • Drexler I., Staib C., Kastenmuller W., Stevanovic S., Schmidt B., Lemonnier F.A., et al. Identification of vaccinia virus epitope-specific HLA-A*0201-restricted T cells and comparative analysis of smallpox vaccines. Proc Natl Acad Sci USA 100 (2003) 217-222
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 217-222
    • Drexler, I.1    Staib, C.2    Kastenmuller, W.3    Stevanovic, S.4    Schmidt, B.5    Lemonnier, F.A.6
  • 12
    • 0037390568 scopus 로고    scopus 로고
    • Quantitation of CD8+ T cell responses to newly identified HLA-A*0201-restricted T cell epitopes conserved among vaccinia and variola (smallpox) viruses
    • Terajima M., Cruz J., Raines G., Kilpatrick E.D., Kennedy J.S., Rothman A.L., et al. Quantitation of CD8+ T cell responses to newly identified HLA-A*0201-restricted T cell epitopes conserved among vaccinia and variola (smallpox) viruses. J Exp Med 197 (2003) 927-932
    • (2003) J Exp Med , vol.197 , pp. 927-932
    • Terajima, M.1    Cruz, J.2    Raines, G.3    Kilpatrick, E.D.4    Kennedy, J.S.5    Rothman, A.L.6
  • 13
    • 2942652411 scopus 로고    scopus 로고
    • Protection against lethal vaccinia virus challenge in HLA-A2 transgenic mice by immunization with a single CD8+ T-cell peptide epitope of vaccinia and variola viruses
    • Snyder J.T., Belyakov I.M., Dzutsev A., Lemonnier F., and Berzofsky J.A. Protection against lethal vaccinia virus challenge in HLA-A2 transgenic mice by immunization with a single CD8+ T-cell peptide epitope of vaccinia and variola viruses. J Virol 78 (2004) 7052-7060
    • (2004) J Virol , vol.78 , pp. 7052-7060
    • Snyder, J.T.1    Belyakov, I.M.2    Dzutsev, A.3    Lemonnier, F.4    Berzofsky, J.A.5
  • 14
    • 25444504038 scopus 로고    scopus 로고
    • HLA class I-restricted responses to vaccinia recognize a broad array of proteins mainly involved in virulence and viral gene regulation
    • Oseroff C., Kos F., Bui H.H., Peters B., Pasquetto V., Glenn J., et al. HLA class I-restricted responses to vaccinia recognize a broad array of proteins mainly involved in virulence and viral gene regulation. Proc Natl Acad Sci USA 102 (2005) 13980-13985
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 13980-13985
    • Oseroff, C.1    Kos, F.2    Bui, H.H.3    Peters, B.4    Pasquetto, V.5    Glenn, J.6
  • 15
    • 26844474948 scopus 로고    scopus 로고
    • HLA-A*0201, HLA-A*1101, and HLA-B*0702 transgenic mice recognize numerous poxvirus determinants from a wide variety of viral gene products
    • Pasquetto V., Bui H.H., Giannino R., Mirza F., Sidney J., Oseroff C., et al. HLA-A*0201, HLA-A*1101, and HLA-B*0702 transgenic mice recognize numerous poxvirus determinants from a wide variety of viral gene products. J Immunol 175 (2005) 5504-5515
    • (2005) J Immunol , vol.175 , pp. 5504-5515
    • Pasquetto, V.1    Bui, H.H.2    Giannino, R.3    Mirza, F.4    Sidney, J.5    Oseroff, C.6
  • 16
  • 17
    • 33745595837 scopus 로고    scopus 로고
    • Identification of vaccinia CD8+ T-cell epitopes conserved among vaccinia and variola viruses restricted by common MHC class I molecules, HLA-A2 or HLA-B7
    • Terajima M., Cruz J., Leporati A.M., Demkowicz Jr. W.E., Kennedy J.S., and Ennis F.A. Identification of vaccinia CD8+ T-cell epitopes conserved among vaccinia and variola viruses restricted by common MHC class I molecules, HLA-A2 or HLA-B7. Hum Immunol 67 (2006) 512-520
    • (2006) Hum Immunol , vol.67 , pp. 512-520
    • Terajima, M.1    Cruz, J.2    Leporati, A.M.3    Demkowicz Jr., W.E.4    Kennedy, J.S.5    Ennis, F.A.6
  • 20
    • 34447341688 scopus 로고    scopus 로고
    • Long-term T cell memory to human leucocyte antigen-A2 supertype epitopes in humans vaccinated against smallpox
    • Ostrout N.D., McHugh M.M., Tisch D.J., Moormann A.M., Brusic V., and Kazura J.W. Long-term T cell memory to human leucocyte antigen-A2 supertype epitopes in humans vaccinated against smallpox. Clin Exp Immunol 149 (2007) 265-273
    • (2007) Clin Exp Immunol , vol.149 , pp. 265-273
    • Ostrout, N.D.1    McHugh, M.M.2    Tisch, D.J.3    Moormann, A.M.4    Brusic, V.5    Kazura, J.W.6
  • 21
    • 34248572100 scopus 로고    scopus 로고
    • Rapid identification of an HLA-B*1501-restricted vaccinia peptide antigen
    • Meyer R.G., Graf C., Britten C.M., Huber C., and Wolfel T. Rapid identification of an HLA-B*1501-restricted vaccinia peptide antigen. Vaccine 25 (2007) 4715-4722
    • (2007) Vaccine , vol.25 , pp. 4715-4722
    • Meyer, R.G.1    Graf, C.2    Britten, C.M.3    Huber, C.4    Wolfel, T.5
  • 22
    • 33947590078 scopus 로고    scopus 로고
    • T-cell epitope discovery for variola and vaccinia viruses
    • Kennedy R., and Poland G.A. T-cell epitope discovery for variola and vaccinia viruses. Rev Med Virol 17 (2007) 93-113
    • (2007) Rev Med Virol , vol.17 , pp. 93-113
    • Kennedy, R.1    Poland, G.A.2
  • 23
    • 4143097915 scopus 로고    scopus 로고
    • Immunodominance in TCD8+ responses to viruses: cell biology, cellular immunology, and mathematical models
    • Yewdell J.W., and Del Val M. Immunodominance in TCD8+ responses to viruses: cell biology, cellular immunology, and mathematical models. Immunity 21 (2004) 149-153
    • (2004) Immunity , vol.21 , pp. 149-153
    • Yewdell, J.W.1    Del Val, M.2
  • 24
    • 19944431356 scopus 로고    scopus 로고
    • Identification of poxvirus CD8+ T cell determinants to enable rational design and characterization of smallpox vaccines
    • Tscharke D.C., Karupiah G., Zhou J., Palmore T., Irvine K.R., Haeryfar S.M., et al. Identification of poxvirus CD8+ T cell determinants to enable rational design and characterization of smallpox vaccines. J Exp Med 201 (2005) 95-104
    • (2005) J Exp Med , vol.201 , pp. 95-104
    • Tscharke, D.C.1    Karupiah, G.2    Zhou, J.3    Palmore, T.4    Irvine, K.R.5    Haeryfar, S.M.6
  • 25
    • 33749528390 scopus 로고    scopus 로고
    • Confronting complexity: real-world immunodominance in antiviral CD8+ T cell responses
    • Yewdell J.W. Confronting complexity: real-world immunodominance in antiviral CD8+ T cell responses. Immunity 25 (2006) 533-543
    • (2006) Immunity , vol.25 , pp. 533-543
    • Yewdell, J.W.1
  • 26
    • 0141573164 scopus 로고    scopus 로고
    • Clonal vaccinia virus grown in cell culture as a new smallpox vaccine
    • Weltzin R., Liu J., Pugachev K.V., Myers G.A., Coughlin B., Blum P.S., et al. Clonal vaccinia virus grown in cell culture as a new smallpox vaccine. Nat Med 9 (2003) 1125-1130
    • (2003) Nat Med , vol.9 , pp. 1125-1130
    • Weltzin, R.1    Liu, J.2    Pugachev, K.V.3    Myers, G.A.4    Coughlin, B.5    Blum, P.S.6
  • 27
    • 7444242665 scopus 로고    scopus 로고
    • ACAM2000 clonal Vero cell culture vaccinia virus (New York City Board of Health strain)-a second-generation smallpox vaccine for biological defense
    • Monath T.P., Caldwell J.R., Mundt W., Fusco J., Johnson C.S., Buller M., et al. ACAM2000 clonal Vero cell culture vaccinia virus (New York City Board of Health strain)-a second-generation smallpox vaccine for biological defense. Int J Infect Dis 8 Suppl 2 (2004) S31-S44
    • (2004) Int J Infect Dis , vol.8 , Issue.SUPPL. 2
    • Monath, T.P.1    Caldwell, J.R.2    Mundt, W.3    Fusco, J.4    Johnson, C.S.5    Buller, M.6
  • 28
    • 0037139478 scopus 로고    scopus 로고
    • Generation of recombinant vaccinia viruses expressing Puumala virus proteins and use in isolating cytotoxic T cells specific for Puumala virus
    • Terajima M., Van Epps H.L., Li D., Leporati A.M., Juhlin S.E., Mustonen J., et al. Generation of recombinant vaccinia viruses expressing Puumala virus proteins and use in isolating cytotoxic T cells specific for Puumala virus. Virus Res 84 (2002) 67-77
    • (2002) Virus Res , vol.84 , pp. 67-77
    • Terajima, M.1    Van Epps, H.L.2    Li, D.3    Leporati, A.M.4    Juhlin, S.E.5    Mustonen, J.6
  • 29
    • 0036606181 scopus 로고    scopus 로고
    • Primary induction of human CD8+ cytotoxic T lymphocytes and interferon-gamma-producing T cells after smallpox vaccination
    • Ennis F.A., Cruz J., Demkowicz Jr. W.E., Rothman A.L., and McClain D.J. Primary induction of human CD8+ cytotoxic T lymphocytes and interferon-gamma-producing T cells after smallpox vaccination. J Infect Dis 185 (2002) 1657-1659
    • (2002) J Infect Dis , vol.185 , pp. 1657-1659
    • Ennis, F.A.1    Cruz, J.2    Demkowicz Jr., W.E.3    Rothman, A.L.4    McClain, D.J.5
  • 30
    • 33646363787 scopus 로고    scopus 로고
    • Using HLA-transgenic mice to identify immunodominant human CD8+ T cell epitopes-does (genome) size matter?
    • Terajima M., and Ennis F.A. Using HLA-transgenic mice to identify immunodominant human CD8+ T cell epitopes-does (genome) size matter?. Immunol Lett 105 (2006) 97-98
    • (2006) Immunol Lett , vol.105 , pp. 97-98
    • Terajima, M.1    Ennis, F.A.2
  • 31
    • 0032503233 scopus 로고    scopus 로고
    • The complete genomic sequence of the modified vaccinia Ankara strain: comparison with other orthopoxviruses
    • Antoine G., Scheiflinger F., Dorner F., and Falkner F.G. The complete genomic sequence of the modified vaccinia Ankara strain: comparison with other orthopoxviruses. Virology 244 (1998) 365-396
    • (1998) Virology , vol.244 , pp. 365-396
    • Antoine, G.1    Scheiflinger, F.2    Dorner, F.3    Falkner, F.G.4
  • 32
    • 33750800848 scopus 로고    scopus 로고
    • Genomic sequence and analysis of a vaccinia virus isolate from a patient with a smallpox vaccine-related complication
    • Li G., Chen N., Feng Z., Buller R.M., Osborne J., Harms T., et al. Genomic sequence and analysis of a vaccinia virus isolate from a patient with a smallpox vaccine-related complication. Virol J 3 (2006) 88
    • (2006) Virol J , vol.3 , pp. 88
    • Li, G.1    Chen, N.2    Feng, Z.3    Buller, R.M.4    Osborne, J.5    Harms, T.6
  • 33
    • 0032146234 scopus 로고    scopus 로고
    • HLA supertypes and supermotifs: a functional perspective on HLA polymorphism
    • Sette A., and Sidney J. HLA supertypes and supermotifs: a functional perspective on HLA polymorphism. Curr Opin Immunol 10 (1998) 478-482
    • (1998) Curr Opin Immunol , vol.10 , pp. 478-482
    • Sette, A.1    Sidney, J.2
  • 34
    • 0033388724 scopus 로고    scopus 로고
    • Nine major HLA class I supertypes account for the vast preponderance of HLA-A and -B polymorphism
    • Sette A., and Sidney J. Nine major HLA class I supertypes account for the vast preponderance of HLA-A and -B polymorphism. Immunogenetics 50 (1999) 201-212
    • (1999) Immunogenetics , vol.50 , pp. 201-212
    • Sette, A.1    Sidney, J.2
  • 35
    • 25844525530 scopus 로고    scopus 로고
    • Classification of A1- and A24-supertype molecules by analysis of their MHC-peptide binding repertoires
    • Sidney J., Southwood S., and Sette A. Classification of A1- and A24-supertype molecules by analysis of their MHC-peptide binding repertoires. Immunogenetics 57 (2005) 393-408
    • (2005) Immunogenetics , vol.57 , pp. 393-408
    • Sidney, J.1    Southwood, S.2    Sette, A.3
  • 36
    • 39649122106 scopus 로고    scopus 로고
    • HLA class I supertypes: a revised and updated classification
    • Sidney J., Peters B., Frahm N., Brander C., and Sette A. HLA class I supertypes: a revised and updated classification. BMC Immunol 9 (2008) 1
    • (2008) BMC Immunol , vol.9 , pp. 1
    • Sidney, J.1    Peters, B.2    Frahm, N.3    Brander, C.4    Sette, A.5
  • 37
    • 29144432729 scopus 로고    scopus 로고
    • Immunodominance of poxviral-specific CTL in a human trial of recombinant-modified vaccinia Ankara
    • Smith C.L., Mirza F., Pasquetto V., Tscharke D.C., Palmowski M.J., Dunbar P.R., et al. Immunodominance of poxviral-specific CTL in a human trial of recombinant-modified vaccinia Ankara. J Immunol 175 (2005) 8431-8437
    • (2005) J Immunol , vol.175 , pp. 8431-8437
    • Smith, C.L.1    Mirza, F.2    Pasquetto, V.3    Tscharke, D.C.4    Palmowski, M.J.5    Dunbar, P.R.6
  • 38
    • 27144560042 scopus 로고    scopus 로고
    • Differential targeting and shifts in the immunodominance of Epstein-Barr virus-specific CD8 and CD4 T cell responses during acute and persistent infection
    • Woodberry T., Suscovich T.J., Henry L.M., Davis J.K., Frahm N., Walker B.D., et al. Differential targeting and shifts in the immunodominance of Epstein-Barr virus-specific CD8 and CD4 T cell responses during acute and persistent infection. J Infect Dis 192 (2005) 1513-1524
    • (2005) J Infect Dis , vol.192 , pp. 1513-1524
    • Woodberry, T.1    Suscovich, T.J.2    Henry, L.M.3    Davis, J.K.4    Frahm, N.5    Walker, B.D.6
  • 39
    • 0036138764 scopus 로고    scopus 로고
    • The magnitude and specificity of influenza A virus-specific cytotoxic T-lymphocyte responses in humans is related to HLA-A and -B phenotype
    • Boon A.C., de Mutsert G., Graus Y.M., Fouchier R.A., Sintnicolaas K., Osterhaus A.D., et al. The magnitude and specificity of influenza A virus-specific cytotoxic T-lymphocyte responses in humans is related to HLA-A and -B phenotype. J Virol 76 (2002) 582-590
    • (2002) J Virol , vol.76 , pp. 582-590
    • Boon, A.C.1    de Mutsert, G.2    Graus, Y.M.3    Fouchier, R.A.4    Sintnicolaas, K.5    Osterhaus, A.D.6
  • 40
    • 0001142643 scopus 로고    scopus 로고
    • Poxviridae: the viruses and their replication
    • Knipe D.M., and Howley P.M. (Eds), Lippincott Wiliams & Wilkins, Philadelphia
    • Moss B. Poxviridae: the viruses and their replication. In: Knipe D.M., and Howley P.M. (Eds). Fields virology, vol 2 (2001), Lippincott Wiliams & Wilkins, Philadelphia 2849-2883
    • (2001) Fields virology, vol 2 , pp. 2849-2883
    • Moss, B.1
  • 41
    • 0000942112 scopus 로고    scopus 로고
    • Epstein-Barr virus and its replication
    • Knipe D.M., and Howley P.M. (Eds), Lippincott Williams & Wilkins, Philadelphia
    • Kieff E., and Rickinson A.B. Epstein-Barr virus and its replication. In: Knipe D.M., and Howley P.M. (Eds). Fields virology, vol 2 (2001), Lippincott Williams & Wilkins, Philadelphia 2511-2573
    • (2001) Fields virology, vol 2 , pp. 2511-2573
    • Kieff, E.1    Rickinson, A.B.2
  • 42
    • 0025900181 scopus 로고
    • Efficient processing of an antigenic sequence for presentation by MHC class I molecules depends on its neighboring residues in the protein
    • Del Val M., Schlicht H.J., Ruppert T., Reddehase M.J., and Koszinowski U.H. Efficient processing of an antigenic sequence for presentation by MHC class I molecules depends on its neighboring residues in the protein. Cell 66 (1991) 1145-1153
    • (1991) Cell , vol.66 , pp. 1145-1153
    • Del Val, M.1    Schlicht, H.J.2    Ruppert, T.3    Reddehase, M.J.4    Koszinowski, U.H.5
  • 43
    • 0031114456 scopus 로고    scopus 로고
    • Point mutation flanking a CTL epitope ablates in vitro and in vivo recognition of a full-length viral protein
    • Yellen-Shaw A.J., Wherry E.J., Dubois G.C., and Eisenlohr L.C. Point mutation flanking a CTL epitope ablates in vitro and in vivo recognition of a full-length viral protein. J Immunol 158 (1997) 3227-3234
    • (1997) J Immunol , vol.158 , pp. 3227-3234
    • Yellen-Shaw, A.J.1    Wherry, E.J.2    Dubois, G.C.3    Eisenlohr, L.C.4
  • 44
    • 0031568385 scopus 로고    scopus 로고
    • Regulation of class I-restricted epitope processing by local or distal flanking sequence
    • Yellen-Shaw A.J., and Eisenlohr L.C. Regulation of class I-restricted epitope processing by local or distal flanking sequence. J Immunol 158 (1997) 1727-1733
    • (1997) J Immunol , vol.158 , pp. 1727-1733
    • Yellen-Shaw, A.J.1    Eisenlohr, L.C.2
  • 46
    • 0021680121 scopus 로고
    • Significance of herpesvirus immediate early gene expression in cellular immunity to cytomegalovirus infection
    • Reddehase M.J., and Koszinowski U.H. Significance of herpesvirus immediate early gene expression in cellular immunity to cytomegalovirus infection. Nature 312 (1984) 369-371
    • (1984) Nature , vol.312 , pp. 369-371
    • Reddehase, M.J.1    Koszinowski, U.H.2
  • 47
    • 0034131201 scopus 로고    scopus 로고
    • The immunogenicity of human and murine cytomegaloviruses
    • Reddehase M.J. The immunogenicity of human and murine cytomegaloviruses. Curr Opin Immunol 12 (2000) 390-396
    • (2000) Curr Opin Immunol , vol.12 , pp. 390-396
    • Reddehase, M.J.1
  • 49
    • 22744444096 scopus 로고    scopus 로고
    • HLA class I transgenic mice: development, utilisation and improvement
    • Pascolo S. HLA class I transgenic mice: development, utilisation and improvement. Expert Opin Biol Ther 5 (2005) 919-938
    • (2005) Expert Opin Biol Ther , vol.5 , pp. 919-938
    • Pascolo, S.1
  • 50
    • 0025729554 scopus 로고
    • Analysis of the HLA-restricted influenza-specific cytotoxic T lymphocyte response in transgenic mice carrying a chimeric human-mouse class I major histocompatibility complex
    • Vitiello A., Marchesini D., Furze J., Sherman L.A., and Chesnut R.W. Analysis of the HLA-restricted influenza-specific cytotoxic T lymphocyte response in transgenic mice carrying a chimeric human-mouse class I major histocompatibility complex. J Exp Med 173 (1991) 1007-1015
    • (1991) J Exp Med , vol.173 , pp. 1007-1015
    • Vitiello, A.1    Marchesini, D.2    Furze, J.3    Sherman, L.A.4    Chesnut, R.W.5
  • 51
    • 0030971268 scopus 로고    scopus 로고
    • HLA-A2.1-restricted education and cytolytic activity of CD8(+) T lymphocytes from beta2 microglobulin (beta2m) HLA-A2.1 monochain transgenic H-2Db beta2m double knockout mice
    • Pascolo S., Bervas N., Ure J.M., Smith A.G., Lemonnier F.A., and Perarnau B. HLA-A2.1-restricted education and cytolytic activity of CD8(+) T lymphocytes from beta2 microglobulin (beta2m) HLA-A2.1 monochain transgenic H-2Db beta2m double knockout mice. J Exp Med 185 (1997) 2043-2051
    • (1997) J Exp Med , vol.185 , pp. 2043-2051
    • Pascolo, S.1    Bervas, N.2    Ure, J.M.3    Smith, A.G.4    Lemonnier, F.A.5    Perarnau, B.6
  • 52
    • 9244231204 scopus 로고    scopus 로고
    • A mouse model of human adaptive immune functions: HLA-A2.1-/HLA-DR1-transgenic H-2 class I-/class II-knockout mice
    • Pajot A., Michel M.L., Fazilleau N., Pancre V., Auriault C., Ojcius D.M., et al. A mouse model of human adaptive immune functions: HLA-A2.1-/HLA-DR1-transgenic H-2 class I-/class II-knockout mice. Eur J Immunol 34 (2004) 3060-3069
    • (2004) Eur J Immunol , vol.34 , pp. 3060-3069
    • Pajot, A.1    Michel, M.L.2    Fazilleau, N.3    Pancre, V.4    Auriault, C.5    Ojcius, D.M.6
  • 53
    • 4143110212 scopus 로고    scopus 로고
    • Boosting T cell-mediated immunity to tyrosinase by vaccinia virus-transduced, CD34(+)-derived dendritic cell vaccination: a phase I trial in metastatic melanoma
    • Di Nicola M., Carlo-Stella C., Mortarini R., Baldassari P., Guidetti A., Gallino G.F., et al. Boosting T cell-mediated immunity to tyrosinase by vaccinia virus-transduced, CD34(+)-derived dendritic cell vaccination: a phase I trial in metastatic melanoma. Clin Cancer Res 10 (2004) 5381-5390
    • (2004) Clin Cancer Res , vol.10 , pp. 5381-5390
    • Di Nicola, M.1    Carlo-Stella, C.2    Mortarini, R.3    Baldassari, P.4    Guidetti, A.5    Gallino, G.F.6
  • 54
    • 41149110035 scopus 로고    scopus 로고
    • Redundancy and plasticity of neutralizing antibody responses are cornerstone attributes of the human immune response to the smallpox vaccine
    • Benhnia M.R., McCausland M.M., Su H.P., Singh K., Hoffmann J., Davies D.H., et al. Redundancy and plasticity of neutralizing antibody responses are cornerstone attributes of the human immune response to the smallpox vaccine. J Virol 82 (2008) 3751-3768
    • (2008) J Virol , vol.82 , pp. 3751-3768
    • Benhnia, M.R.1    McCausland, M.M.2    Su, H.P.3    Singh, K.4    Hoffmann, J.5    Davies, D.H.6
  • 55
    • 33746149648 scopus 로고    scopus 로고
    • HLA-A2-restricted human CD8(+) cytotoxic T lymphocyte responses to a novel epitope in vaccinia virus that is conserved among orthopox viruses
    • Dong Y., and Denny T.N. HLA-A2-restricted human CD8(+) cytotoxic T lymphocyte responses to a novel epitope in vaccinia virus that is conserved among orthopox viruses. J Infect Dis 194 (2006) 168-175
    • (2006) J Infect Dis , vol.194 , pp. 168-175
    • Dong, Y.1    Denny, T.N.2
  • 56
    • 0028052724 scopus 로고
    • Scheme for ranking potential HLA-A2 binding peptides based on independent binding of individual peptide side-chains
    • Parker K.C., Bednarek M.A., and Coligan J.E. Scheme for ranking potential HLA-A2 binding peptides based on independent binding of individual peptide side-chains. J Immunol 152 (1994) 163-175
    • (1994) J Immunol , vol.152 , pp. 163-175
    • Parker, K.C.1    Bednarek, M.A.2    Coligan, J.E.3


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