Formulation and evaluation of bi-layer tablet of metoclopramide hydrochloride and ibuprofen

AAPS PharmSciTech

Volumn 9, Issue 3, 2008, Pages 818-827

  Shiyani, Bhavesh ^a   Gattani, Surendra ^a   Surana, Sanjay ^a  

^a R C PATEL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH   (India)

Author keywords

Bi layer tablet; Gellangum; Ibuprofen; Metoclopramide hydrochloride

Indexed keywords

AGAR; BICARBONATE; CROSCARMELLOSE SODIUM; CROSPOVIDONE; DISINTEGRATING AGENT; GELLAN; HYDROXYPROPYLMETHYLCELLULOSE; IBUPROFEN; METOCLOPRAMIDE; NONSTEROID ANTIINFLAMMATORY AGENT; POVIDONE; STARCH GLYCOLATE SODIUM;

ARTICLE; CONTROLLED RELEASE FORMULATION; DRUG ABSORPTION; DRUG EFFICACY; DRUG RELEASE; DRUG SOLUBILITY; HYDROPHILICITY; IMMEDIATE RELEASE FORMULATION; MIGRAINE; PARTICLE SIZE; STOMACH MOTILITY; SUSTAINED RELEASE FORMULATION; TABLET DISINTEGRATION; TABLET FORMULATION; THIN LAYER CHROMATOGRAPHY; WETTABILITY;

CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DRUG COMBINATIONS; DRUG EVALUATION, PRECLINICAL; IBUPROFEN; METOCLOPRAMIDE; TABLETS;

EID: 57149132977     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-008-9116-y     Document Type: Article

References (18)

1. W. C. Gunsel. Compression-coated and layer tablet. In A.H. Lieberman (ed.), Pharmaceutical dosage forms: Tablets, Decker, New York, 1989, pp. 274-284.
2. B. G. Wells, J. T. DiPiro, T. L. Schwinghammer, and C. W. Hamilton. Pharmacotherapy Handbook, McGraw-Hill, New York, 2006, pp. 535-547.
3. J. D. Higgins, T. P. Gilmor, S. A. Martellucci, and R. D. Bruce. IB. In H. G. Brittain (ed.), Analytical profiles of drug substances and excipients, Elsevier, New Delhi, India, 2001, p. 294.
4. U. S. Bagul, N. S. Bagul, M. S. Kulkarni, S. D. Swant, N. K. Gujar, and A. A. Bidkar. Current status of tablet disintegrants: A review. Available at: http://www.pharmainfo.net. Accessed July 8, 2006.
5. I. Akihiko, and S. Masayasu. Development of oral dosage form for elderly patients: Use of agar as base of rapidly disintegrating tablets. Chem. Pharm. Bull. 45: 2132-2136 (1996).
6. F. Ohwoavworhua, and T. Adelakun. Phosphoric acid-mediated depolymerization and decrystallization of α-Cellulose obtained from corn cob: Preparation of low crystallinity cellulose and some physicochemical properties. Trop. J. Pharm. Res. 4 2:509-516 (2004).
7. K. R. Reddy, S. Mutalik, and S. Reddy. One-daily sustained-release matrix tablets of nicorandil: Formulation and in vitro evaluation. AAPS PharmSciTech. 4 4:E61 (2003).
8. A. I. Magnus, and O. Anthony. Preliminary investigation into the use of pleurotus tuber-regium powder as a tablet disintegrant. Trop. J. Pharm. Res. 1 1:29-37 (2002).
9. G. Jain, and J. Goswami. Studies on formulation and evaluation of new superdisintegrants for dispersible tablets. Int. J. Pharmaceut Excipient. 37-43 (2005).
10. T. Bussemera, N. Peppasb, and R. Bodmeiera. Evaluation of the swelling, hydration and rupturing pulsatile drug delivery system. Eur. J. Pharm. Biopharm. 56: 261-270 (2006).
11. P. W. Heng, and L. W. Chah. Drug substance and excipient characterization. In D. M. Parikh (ed.), Handbook of Pharmaceutical Granulation Technology, 81:DEcker, New York, 1997, pp. 52-55.
12. Indian Pharmacopoeia. Controller of publications New Delhi, 1996.
13. USP/NF. Physical Tests: Disintegration (701). 22/17 ed. Rockville, MD: United StatesPharmacopeial Convention Inc; 1990.
14. M. Mutasem, and Q. Rawas. Fast-disintegrating sublingual tablets: Effect of epinephrine load on tablet characteristics. AAPS PharmSciTech. 7 2:E1-E7 (2006).
15. N. Zhao, and L. L. Augsburger. Functional comparison of 3 classes of disintegrants in promoting aspirin tablet disintegration and dissolution. AAPS PharmSciTech. 6 4:E634-E640 (2005 Dec 12).
16. A. M. Hamid, M. S. Harris, T. Jaweria, and I. Y. Rabia. Once-daily tablet formulation and in vitro release evaluation of cefpodoxime using hydroxypropyl methylcellulose: A technical note. AAPS PharmSciTech. 7 (3):E1-E6 (2006).
17. L. L. Augsburger, A. W. Brzecko, U. Shah, and H. A. Hahm. Characterization and functionality of super disintegrants. In J. Swarbrick, and J. C. Boylan (eds.), Encyclopedia of Pharmaceutical Technology, Dekker, New York, NY, 2000, pp. 269-291.
18. N. Zhao, and L. L. Augsburger. The influence of swelling capacity of superdisintegrants in different pH media on the dissolution of hydrochlorothiazide from directly compressed tablets. AAPS PharmSciTech. 6 1:E120-E126 (2005 Sep 20).