Increased risk of falling in older community-dwelling women with mild cognitive impairment

Physical Therapy

Volumn 88, Issue 12, 2008, Pages 1482-1491

  Liu Ambrose, Teresa Y ^a   Ashe, Maureen C ^a   Graf, Peter ^a   Beattie, B Lynn ^a   Khan, Karim M ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; AGING; ARTICLE; BODY MASS; BODY POSTURE; BRAIN FUNCTION; CLINICAL ASSESSMENT; COGNITION; COGNITIVE DEFECT; COMORBIDITY; CONTRAST SENSITIVITY; DISEASE CLASSIFICATION; FALLING; FEMALE; FUNCTIONAL ASSESSMENT; HAND MOVEMENT; HUMAN; MAJOR CLINICAL STUDY; MILD COGNITIVE IMPAIRMENT; MINI MENTAL STATE EXAMINATION; MONTREAL COGNITIVE ASSESSMENT; MUSCLE STRENGTH; NEUROLOGIC EXAMINATION; PHYSICAL ACTIVITY; PHYSIOLOGICAL PROFILE ASSESSMENT; PROPRIOCEPTION; PSYCHOLOGIC ASSESSMENT; PSYCHOLOGIC TEST; QUADRICEPS FEMORIS MUSCLE; RATING SCALE; RESPONSE TIME; RISK ASSESSMENT; RISK FACTOR; SCORING SYSTEM; SCREENING TEST; STROOP COLOR WORD TEST; VERBAL DIGITS BACKWARD TEST; WORKING MEMORY;

ACCIDENTAL FALLS; AGED; CAUSALITY; COGNITION DISORDERS; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; RISK ASSESSMENT;

EID: 57149098596     PISSN: 00319023     EISSN: None     Source Type: Journal    
DOI: 10.2522/ptj.20080117     Document Type: Article

References (60)

1. Exton-Smith AN. Functional consequences of ageing: clinical manifestations. In: Exton-Smith AN, Evans JG, eds. Care of the Elderly: Meeting the Challenge of Dependency. London, United Kingdom: Academic Press; 1977.
2. Evans JG. Fallers, non-fallers and Poisson. Age Ageing. 1990;19:268-269.
3. Carter ND, Kannus P, Khan KM. Exercise in the prevention of falls in older people: a systematic literature review examining the rationale and the evidence. Sports Med. 2001;31:427-438.
4. Tinetti ME, Speechley M, Ginter SF. Risk factors for falls among elderly persons living in the community. N Engl J Med. 1988;319:1701-1707.
5. van Dijk PT, Meulenberg OG, van de Sande HJ, et al. Falls in dementia patients. Gerontologist. 1993;33:200-204.
6. Buchner DM, Larson EB. Falls and fractures in patients with Alzheimer-type dementia. JAMA. 1987;257:1492-1495.
7. Shaw FE. Falls in cognitive impairment and dementia. Clin Geriatr Med. 2002;18:159-173.
8. Petersen RC, Doody R, Kurz A, et al. Current concepts in mild cognitive impairment. Arch Neurol. 2001;58:1985-1992.
9. Feldman HH, Jacova C. Mild cognitive impairment. Am J Geriatr Psychiatry. 2005;13:645-655.
10. Petersen RC, Smith GE, Waring SC, et al. Mild cognitive impairment: clinical characterization and outcome. Arch Neurol. 1999;56:303-308.
11. Busse A, Bischkopf J, Riedel-Heller SG, et al. Mild cognitive impairment: prevalence and incidence according to different diagnostic criteria - results of the Leipzig Longitudinal Study of the Aged (LEILA75+). Br J Psychiatry. 2003;182:449-454.
12. The Canadian Study of Health and Aging: risk factors for Alzheimer's disease in Canada. Neurology. 1994;44:2073-2080.
13. Graham JE, Rockwood K, Beattie BL, et al. Prevalence and severity of cognitive impairment with and without dementia in an elderly population. Lancet. 1997;349:1793-1796.
14. Franssen EH, Souren LE, Torossian CL, et al. Equilibrium and limb coordination in mild cognitive impairment and mild Alzheimer's disease. J Am Geriatr Soc. 1999;47:463-469.
15. Aggarwal NT, Wilson RS, Beck TL, et al. Motor dysfunction in mild cognitive impairment and the risk of incident Alzheimer disease. Arch Neurol. 2006;63:1763-1769.
16. Wylie SA, Ridderinkhof KR, Eckerle MK, et al. Inefficient response inhibition in individuals with mild cognitive impairment. Neuropsychologia. 2007;45:1408-1419.
17. Rapport LJ, Hanks RA, Millis SR, et al. Executive functioning and predictors of falls in the rehabilitation setting. Arch Phys Med Rehabil. 1998;79:629-633.
18. Lord SR, Menz HB, Tiedemann A. A physiological profile approach to falls risk assessment and prevention. Phys Ther. 2003;83:237-252.
19. Lord SR, Sherrington C, Menz H. A Physiological Profile Approach for Falls Prevention: Falls in Older People - Risk Factors and Strategies for Prevention. Cambridge, United Kingdom: Cambridge University Press; 2001:221-238.
20. Nevitt MC, Cummings SR, Hudes ES. Risk factors for injurious falls: a prospective study. J Gerontol. 1991;46:M164-M170.
21. Liu-Ambrose TY, Ahamed Y, Graf P, et al. Older fallers with poor executive functioning overestimate their postural limits. Arch Phys Med Rehabil. 2008;89:1335-1340.
22. Persad CC, Giordani B, Chen HC, et al. Neuropsychological predictors of complex obstacle avoidance in healthy older adults. J Gerontol B Psychol Sci Soc Sci. 1995;50:P272-P277.
23. Folstein MF, Folstein SE, McHugh PR. "Mini-mental state": a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12:189-198.
24. Berger AK, Fratiglioni L, Winblad B, et al. Alzheimer's disease and depression: preclinical comorbidity effects on cognitive functioning. Cortex. 2005;41:603-612.
25. Yesavage JA. Geriatric depression scale. Psychopharmacol Bull. 1988;24:709-711.
26. Groll DL, To T, Bombardier C, et al. The development of a comorbidity index with physical function as the outcome. J Clin Epidemiol. 2005;58:595-602.
27. Abbott RD, White LR, Ross GW, et al. Walking and dementia in physically capable elderly men. JAMA. 2004;292:1447-1453.
28. Weuve J, Kang JH, Manson JE, et al. Physical activity, including walking, and cognitive function in older women. JAMA. 2004;292:1454-1461.
29. Washburn RA, Smith KW, Jette AM, et al. The Physical Activity Scale for the Elderly (PASE): development and evaluation. J Clin Epidemiol. 1993;46:153-162.
30. Washburn RA, McAuley E, Katula J, et al. The Physical Activity Scale for the Elderly (PASE): evidence for validity. J Clin Epidemiol. 1999;52:643-651.
31. Washburn RA, Smith KW, Jette AM, et al. Physical Activity Scale for the Elderly: Administration and Scoring Instruction Manual. Watertown, MA: New England Research Institute; 1991.
32. Podsiadlo D, Richardson S. The Timed "Up & Go": a test of basic functional mobility for frail elderly persons. J Am Geriatr Soc. 1991;39:142-148.
33. Shumway-Cook A, Brauer 5, Woollacott M. Predicting the probability for falls in community-dwelling older adults using the Timed "Up & Go" Test. Phys Ther. 2000;80:896-903.
34. Portet F, Ousset PJ, Visser PJ, et al. Mild cognitive impairment (MCI) in medical practice: a critical review of the concept and new diagnostic procedure. Report of the MCI Working Group of the European Consortium on Alzheimer's Disease. J Neurol Neurosurg Psychiatry. 2006;77:714-718.
35. Nasreddine ZS, Phillips NA, Bedirian V, et al. The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment. J Am Geriatr Soc. 2005;53:695-699.
36. Lord S, Clark R, Webster I. Physiological factors associated with falls in an elderly population. J Am Geriatr Soc. 1991;39:1194-1200.
37. Lord S, Sambrook P, Gilbert C, et al. Postural stability, falls and fractures in the elderly: results from the Dubbo Osteoporosis Epidemiology Study. Med J Aust. 1994;160:684-691.
38. Lord S, Ward J, Williams P, et al. Physiological factors associated with falls in older community-dwelling women. J Am Geriatr Soc. 1994;42:1110-1117.
39. Miyake A, Friedman NP, Emerson MJ, et al. The unity and diversity of executive functions and their contributions to complex "frontal lobe" tasks: a latent variable analysis. Cogn Psychol. 2000;41:49-100.
40. Spreen O, Strauss E. A Compendium of Neurological Tests. 2nd ed. New York, NY: Oxford University Press Inc; 1998.
41. Wechsler D. Wechsler Adult Intelligence Scale-Revised. San Antonio, TX: The Psychological Corporation; 1981.
42. Trenerry M, Crosson B, DeBoe J, et al. Stroop Neuropsychological Screening Test. Lutz, FL: Psychological Assessment Resources Inc; 1988.
43. Lezak MD. Neuropsychological Assessment. 3rd ed. New York, NY: Oxford University Press; 1995.
44. Cummings S, Nevitt M, Kidd S. Forgetting falls: the limited accuracy of recall of falls in the elderly. J Am Geriatr Soc. 1988;36:613-616.
45. Lord S, Fitzpatrick R. Choice stepping reaction time: a composite measure of fall risk in older people. J Gerontol. 2001;10:M627-M632.
46. Lundin-Olsson L, Nyberg L, Gustafson Y. "Stops walking when talking" as a predictor of falls in elderly people. Lancet. 1997;349:617.
47. Starr JM, Leaper SA, Murray AD, et al. Brain white matter lesions detected by magnetic resonance imaging are associated with balance and gait speed. J Neurol Neurosurg Psychiatry. 2003;74:94-98.
48. Rabbitt PM, Scott M, Thacker N, et al. Balance marks cognitive changes in old age because it reflects global brain atrophy and cerebro-arterial blood-flow. Neuropsychologia. 2006;44:1978.
49. Onen F, Feugeas MC, Baron G, et al. Leukoaraiosis and mobility decline: a high resolution magnetic resonance imaging study in older people with mild cognitive impairment. Neurosci Lett. 2004;355:185-188.
50. Whitman GT, Tang Y, Lin A, et al. A prospective study of cerebral white matter abnormalities in older people with gait dysfunction. Neurology. 2001;57:990-994.
51. Rosano C, Aizenstein HJ, Studenski S, et al. A regions-of-interest volumetric analysis of mobility limitations in community-dwelling older adults. J Gerontol A Biol Sci Med Sci. 2007;62:1048-1055.
52. de Groot JC, de Leeuw FE, Oudkerk M, et al. Cerebral white matter lesions and cognitive function: the Rotterdam Scan Study. Ann Neurol. 2000;47:145-151.
53. Gunning-Dixon FM, Raz N. Neuroanatomical correlates of selected executive functions in middle-aged and older adults: a prospective MRI study. Neuropsychologia. 2003;41:1929-1941.
54. Kuo HK, Lipsitz LA. Cerebral white matter changes and geriatric syndromes: is there a link? J Gerontol A Biol Sci Med Sci. 2004;59:818-826.
55. Knopman DS, Edland SD, Cha RH, et al. Incident dementia in women is preceded by weight loss by at least a decade. Neurology. 2007;69:739-746.
56. Tinetti ME, Doucette J, Claus E, et al. Risk factors for serious injury during falls by older persons in the community. J Am Geriatr Soc. 1995;43:1214-1221.
57. Colcombe S, Kramer AF. Fitness effects on the cognitive function of older adults: a meta-analytic study. Psychol Sci. 2003;14:125-130.
58. Campbell J, Robertson M, Gardner M, et al. Randomised controlled trial of a general practice programme of home based exercise to prevent falls in elderly women. BMJ. 1997;315:1065-1069.
59. Close J, Ellis M, Hooper R, et al. Prevention of Falls in the Elderly Trial (PROFET): a randomised controlled trial. Lancet. 1999;353:93-97.
60. Shaw FE, Bond J, Richardson DA et al. Multifactorial intervention after a fall in older people with cognitive impairment and dementia presenting to the accident and emergency department: randomised controlled trial. BMJ. 2003;326:73.