Use of Penalized Splines in Extended Cox-Type Additive Hazard Regression to Flexibly Estimate the Effect of Time-varying Serum Uric Acid on Risk of Cancer Incidence: A Prospective, Population-Based Study in 78,850 Men

Annals of Epidemiology

Volumn 19, Issue 1, 2009, Pages 15-24

  Strasak, Alexander M ^a   Lang, Stefan ^b   Kneib, Thomas ^c   Brant, Larry J ^d   Klenk, Jochen ^e   Hilbe, Wolfgang ^a   Oberaigner, Willi ^f   Ruttmann, Elfriede ^a   Kaltenbach, Lalit ^a   Concin, Hans ^g   Diem, Günter ^g   Pfeiffer, Karl P ^a   Ulmer, Hanno ^a,g  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b UNIVERSITY OF INNSBRUCK   (Austria)

^c UNIVERSITY OF MUNICH   (Germany)

^d NATIONAL INSTITUTE ON AGING   (United States)

^e UNIVERSITY OF ULM   (Germany)

^f Tyrolean State Hospitals Ltd   (Austria)

^g AGENCY FOR PREVENTIVE AND SOCIAL MEDICINE   (Austria)

Author keywords

Cancer incidence; Epidemiology; Extended Cox type additive hazard regression; Men; Penalized splines; Risk factor; Serum uric acid

Indexed keywords

URIC ACID;

ADULT; ANALYTIC METHOD; ARTICLE; CANCER INCIDENCE; CANCER RISK; CONFIDENCE INTERVAL; FOLLOW UP; HAZARD RATIO; HUMAN; MAJOR CLINICAL STUDY; MALE; PENALIZED SPLINE; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; URIC ACID BLOOD LEVEL;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; HUMANS; INCIDENCE; MALE; MIDDLE AGED; NEOPLASMS; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; TIME FACTORS; URIC ACID; YOUNG ADULT;

EID: 57049173410     PISSN: 10472797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.annepidem.2008.08.009     Document Type: Article

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