Rapidly progressive neurological deterioration in a child with Alpers syndrome exhibiting a previously unremarkable brain MRI

Neuropediatrics

Volumn 39, Issue 3, 2008, Pages 179-183

  Brunetti Pierri, N ^a   Selby, K ^b   O'Sullivan, M ^b   Hendson, C ^b   Truong, C ^a   Waters, P J ^b   Wong, L J ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Alpers syndrome; DNA polymerase gamma; Mitochondrial DNA depletion; POLG

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; MITOCHONDRIAL ENZYME; POLYMERASE GAMMA; UNCLASSIFIED DRUG;

ALPERS DISEASE; ARTICLE; BIOCHEMISTRY; BRAIN ATROPHY; CASE REPORT; CEREBELLUM ATROPHY; CLINICAL FEATURE; DEVELOPMENTAL DISORDER; DISEASE COURSE; DNA DETERMINATION; EPILEPTIC STATE; FAMILY HISTORY; GENE MUTATION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMAGE DISPLAY; LETHARGY; MALE; MICROCEPHALY; MYOCLONUS; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN CEREBROSPINAL FLUID LEVEL; PSYCHOMOTOR RETARDATION; SEIZURE;

BRAIN; DIFFUSE CEREBRAL SCLEROSIS OF SCHILDER; DISEASE PROGRESSION; DNA, MITOCHONDRIAL; DNA-DIRECTED DNA POLYMERASE; FEMALE; HUMANS; INFANT; MAGNETIC RESONANCE IMAGING; MUTATION;

EID: 57049154814     PISSN: 0174304X     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0028-1093334     Document Type: Article

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