Virtual electrodes and the induction of fibrillation in Langendorff-perfused rabbit ventricles: The role of intracellular calcium

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 295, Issue 4, 2008, Pages

  Hayashi, Hideki ^a,c   Lin, Shien Fong ^a,b   Joung, Boyoung ^b   Karagueuzian, Hrayr S ^a   Weiss, James N ^a   Chen, Peng Sheng ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

Author keywords

Electrical stimulation; Mapping

Indexed keywords

CALCIUM; RYANODINE; THAPSIGARGIN;

ACTION POTENTIAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CONTROL GROUP; CONTROLLED STUDY; ELECTRODE; EPICARDIUM; HEART PACING; HEART VENTRICLE FIBRILLATION; ISOLATED HEART; NONHUMAN; PRIORITY JOURNAL; RABBIT; SARCOPLASMIC RETICULUM;

ACTION POTENTIALS; ANIMALS; CALCIUM SIGNALING; DISEASE MODELS, ANIMAL; ELECTRIC STIMULATION; ENZYME INHIBITORS; HEART VENTRICLES; MYOCYTES, CARDIAC; PERFUSION; PERICARDIUM; RABBITS; RYANODINE; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; THAPSIGARGIN; TIME FACTORS; VENTRICULAR FIBRILLATION;

EID: 57049118616     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00001.2008     Document Type: Article

References (16)

1. Choi BR, Salama G. Simultaneous maps of optical action potentials and calcium transients in guinea-pig hearts: mechanisms underlying concordant alternans. J Physiol 529: 171-188, 2000.
2. Efimov IR, Cheng Y, Van Wagoner DR, Mazgalev T, Tchou PJ. Virtual electrode-induced phase singularity: a basic mechanism of defibrillation failure. Circ Res 82: 918-925, 1998.
3. m in myocyte cultures. Circ Res 94: 1589-1597, 2004.
4. Fast VG, Ideker RE. Simultaneous optical mapping of transmembrane potential and intracellular calcium in myocyte cultures. J Cardiovasc Electrophysiol 11: 547-556, 2000.
5. Hayashi H, Kamanu SD, Ono N, Kawase A, Chou CC, Weiss JN, Karagueuzian HS, Lin SF, Chen PS. Calcium transient dynamics and the mechanisms of ventricular vulnerability to single premature electrical stimulation in Langendorff-perfused rabbit ventricles. Heart Rhythm 5: 116-123, 2008.
6. Hwang GS, Hayashi H, Tang L, Ogawa M, Hernandez H, Tan AY, Li H, Karagueuzian HS, Weiss JN, Lin SF, Chen PS. Intracellular calcium and vulnerability to fibrillation and defibrillation in Langendorff-perfused rabbit ventricles. Circulation 114: 2595-2603, 2006.
7. Lin SF, Han J, Qian YW, Province RR, Sung J. Virtual electrodes in the termination of ventricular fibrillation in protective zones. Proc First Joint BMES/EMBS Conf 5: 55, 1999.
8. Lin SF, Roth BJ, Wikswo JP Jr. Quatrefoil reentry in myocardium: an optical imaging study of the induction mechanism. J Cardiovasc Electrophysiol 10: 574-586, 1999.
9. Omichi C, Lamp ST, Lin SF, Yang J, Baher A, Zhou S, Attin M, Lee MH, Karagueuzian HS, Kogan B, Qu Z, Garfinkel A, Chen PS, Weiss JN. Intracellular Ca dynamics in ventricular fibrillation. Am J Physiol Heart Circ Physiol 286: H1836-H1844, 2004.
10. m in myocyte cultures and computer model: dependence on the timing of shock application. Cardiovasc Res 73: 101-110, 2007.
11. Sepulveda NG, Roth BJ, Wikswo JPJ. Current injection into a two-dimensional anisotropic bidomain. Biophys J 55: 987-999, 1989.
12. 2+ and ryanodine. J Mol Cell Cardiol 19: 841-851, 1987.
13. Trayanova N, Skouibine K, Moore P. Virtual electrode effects in defibrillation. Prog Biophys Mol Biol 69: 387-403, 1998.
14. Weiss JN, Karma A, Shiferaw Y, Chen PS, Garfinkel A, Qu Z. From pulsus to pulseless: the saga of cardiac alternans. Circ Res 98: 1244-1253, 2006.
15. Wikswo JP Jr, Wisialowski TA, Altemeier WA, Balser JR, Kopelman HA, Roden DM. Virtual cathode effects during stimulation of cardiac muscle. Two-dimensional in vivo experiments. Circ Res 68: 513-530, 1991.
16. Worthington MG, Opie LH. Effects of calcium channel agonism by Bay-K-8644 on ventricular fibrillation threshold of isolated heart. Cardiovasc Drugs Ther 6: 597-604, 1992.