Aflatoxins as a risk factor for hepatocellular carcinoma in Egypt, Mansoura Gastroenterology Center Study

Hepato-Gastroenterology

Volumn 55, Issue 86-87, 2008, Pages 1754-1759

  Abdel Wahab, Mohamed ^a   Mostafa, M ^a   Sabry, M ^b   El Farrash, M ^b   Yousef, Tamer ^a  

^a MANSOURA UNIVERSITY   (Egypt)

^b MANSOURA UNIVERSITY   (Egypt)

Author keywords

Aflatoxins; Egypt; HBs; HCV; Hepatocellular carcinoma

Indexed keywords

AFLATOXIN B1; ALANINE AMINOTRANSFERASE; ALPHA FETOPROTEIN; ANTIMONY TARTRATE; HEPATITIS B SURFACE ANTIBODY; HEPATITIS C ANTIBODY; PRAZIQUANTEL;

ADULT; AGED; AGRICULTURAL WORKER; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; CANCER RISK; CONTROLLED STUDY; EGYPT; FEMALE; GOVERNMENT; HEPATITIS C; HIGH RISK POPULATION; HUMAN; INCIDENCE; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; OCCUPATION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RESIDENTIAL AREA; RISK FACTOR; SCHISTOSOMIASIS; SEX DIFFERENCE; TUMOR VOLUME; URBAN RURAL DIFFERENCE;

ADULT; AFLATOXIN B1; AGED; ALANINE TRANSAMINASE; CARCINOMA, HEPATOCELLULAR; FEMALE; HUMANS; LIVER NEOPLASMS; MALE; MIDDLE AGED; RISK FACTORS;

EID: 57049113237     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Akriviadis EA, Llovet JM, Efremidis SC, Shouval D, Canelo R, Ringe B, Mevers WC: Hepatocellular carcinoma. Br J Surg 1998; 85(10):1319-1331.
2. Okuda K: Hepatocellular carcinoma. J Hepatol 2000; 32(1):225-237.
3. Abdel-Wahab M, El-Ghawalby N, Mostafa M, Sultan A, El-Sadany M, Fathy O, Salah T, Ezzat F: Epidemiology of Hepatocellular Carcinoma in Lower Egypt, Mansoura Gastroenterology Center. Hepatogastroenterology 2007; 54:157-162.
4. El-Serag HB: Hepatocellular Carcinoma: An Epidemiologic View. Yale University Workshop on Hepatocellular Carcinoma. J Clin Gastroenterol 2002; 35(5):S72-S78.
5. Tiemersma EW, Omer RE, Bunschoten A, van't Veer P, Kok FJ, Idris MO, Kadaru AMY, Fedail SS, Kampman E: Cancer Epidemiology. Biomarkers Prevent 2001; 10:785-791.
6. Tilton SC, Orner GA, Benninghoff AD, Carpenter HM, Hendricks JD, Pereira CB, Williams DE: Genomic profiling reveals an alternate mechanism for hepatic tumor promotion by perfluorooctanoic acid in rainbow trout. Environ Health Perspect 2008; 116(8):1047-1055
7. Wang J-S, Kensler TW, Groopman JD: Toxicants in food: fungal contaminants. In: Ioannides C (Ed.). Current Toxicology Series: Nutrition and Chemical Toxicity. New York: Wiley, 1998; pp. 29-57.
8. Massey TE: The 1995 Pharmacological Society of Canada Merck Frosst Award. Cellular and molecular targets in pulmonary chemical carcinogenesis: studies with aflatoxin B1. Can J Physiol Pharmacol 1996; 74(6):621-628.
9. Wang JS, Groopman JD: DNA damage by mycotoxins. Mutat Res 1999; 424(1-2):167-181.
10. Wild CP, Turner PC: The toxicology of aflatoxins as a basis for public health decisions. Mutagenesis 2002; 17(6):471-481.
11. Schafer DF, Sorrell MF: Hepatocellular carcinoma. Lancet 1999; 353(9160):1253-1257.
12. Abdel-Wahab M, Sultan A, el-Ghawalby N, Fathy O, Abou-Zeid M, Abou El-Enein A, Abdallah T, Fouad A, Kandeel T, el-Shobari M, el-Fiky A, el-Ebidey G, Gadel-Hak N, Ezzat F: Hepatic resection in cirrhotic liver for treatment of hepatocellular carcinoma in Egyptian patients. Experience with 140 cases in a single center. Hepatogastroenterology 2004; 51(56):559-563.
13. Hifnawy MS, Mangoud AM, Eissa MH, Nor Edin E, Mostafa Y, Abouel-Magd Y, Sabee EI, Amin I, Ismail A, Morsy TA, Mahrous S, Afefy AF, el-Shorbagy E, el-Sadawy M, Ragab H, Hassan MI, el-Hady G, Saber M: The role of aflatoxin-contaminated food materials and HCV in developing hepatocellular carcinoma in Al-Sharkia Governorate, Egypt. J Egypt Soc Parasitol 2004; 34(1):479-488.
14. Verardi G, De Froidmont-Gartz I: Overview on community legislation in the field of official control of mycotoxins in feedingstuffs. Nat Toxins 1995; 3(4):248-256.
15. Aziz NH, Youssef YA: Occurrence of aflatoxins and aflatoxin-producing moulds in fresh and processed meat in Egypt. Food Addit Contam 1991; 8(3):321-331.
16. El-Zayadi Aa Abaza H, Shawky S, Mostafa K, Osaima E, Hanaa MB: Prevalence and epidemiological features of hepatocellular carcinoma in Egypt - a single center experience. Hepatology Research 2001; 19:170-179.
17. Okuda K, Ohtsuki T, Obata H, Tomimatsu M, Okazaki N, Hasegawa H, Nakajima. Y, Ohnishi K. Natural history of hepatocellular carcinoma and prognosis in relation to treatment. Study of 850 patients. Cancer 1985; 56(4):918-928.
18. Abdel-Wahab M, Abou El-Enein A, Abou-Zeid M, El-Fiky A, Abdallah T, FawZy M, Fouad A, Sultan A, Fathy O, El-Ebidey G, Elghawalby N, Ezzat F. Hepatocellular carcinoma in Mansura-Egypt: Exoerience of 385 patients at a single center. Hepatogastroenterology 2000; 47(33):663-668.
19. Nelly H, Heba M, Nadia M, Samir S, Nazly G: Review of epidemiologic and clinicopathologic features of 403 hepatocellular carcinoma (HCC) patients. J Egyptian Nat Cancer Inst 2000; 12(2):87-93.
20. Yates SC, Hafez M, Beld M, Lukashov VV, Hassan Z, Carboni G, Khaled H, Mcmorrow M, Attia M, Goudsmit J: Hepatocellular carcinoma in Egyptians with and without a history of hepatitis B virus infection: association with hepatitis C virus (HCV) infection but not with (HCV) RNA level. Am J Trop Med Hyg 1999; 60(4):714-720.
21. Ahsan H, Wang L-Y, Chen C-J, Tsai W-Y, Santella RM: Variability in aflatoxin-albumin adduct Levels and effects of hepatitis B and C virus infection and Glutathione S-transferase M1 and T1 Genotype. Environ Health Perspect 2001; 109(8):833-837.
22. Edmondson HA, Craig JR: Neoplasns of the liver cancer. In: Schiff L, Schiff ER (Eds.). Diseases of the liver. 6th Edition. Philadelphia: Lippincott Campany, 1987; pp. 1118-1157.
23. Sun CA, Wu DM, Wang LY, Chen CJ, You SL, Santella RM: Determinants of formation of aflatoxin-albumin adducts: a seventownship study in Taiwan. Br J Cancer 2002; 87:966-970.
24. Tanaka E: Gender-related differences in pharmacokinetics and their clinical significance. J Clin Pharm Ther 1999; 24:339-346.
25. Ghaffar YA, Fattah SA, Kamel M, Badr RM, Mohomed FF, Strickland GT: The impact of endemic schistosomiasis on acute viral hepatitis. Am J Trop Med Hyg 1991; 45(6):743-750.
26. Halim AB, Garry RF, Dash S, Gerber MA: Effect of schistosomiasis and hepatitis on liver disease. Am J Trop Med Hyg 1999; 60(6):915-920.
27. El-Zayadi AR, Selim O, Ibrahim EH, Hamdy H, Dabbous H, Ahdy A, Moneim SA: Does schistosomiasis play a role in the high sero prevalence of HCV antibody among Egyptians? Trop Gastroenterol 1997; 18(3):98-100.
28. Toteja GS, Mukherjee A, Diwakar S, Singh P, Saxena BN, Sinha KK, Sinha AK, Kumar N, Nagaraja KV, Bai G, Prasad CA, Vanchinathan S, Roy R, Parkar S: Aflatoxin B1 contamination in wheat grain samples collected from different geographical regions of India: A multicenter. J Food Prot 2006; 69(6):1463-1467.
29. Bhat RV, Vasanthi S, Rao BS, Rao RN, Rao VS, Nagaraja KV, Bai RG, Prasad CA, Vanchinathan S, Roy R, Saba S, Mukherjee A, Ghosh PK, Toteja GS, Saxena BN: Aflatoxin B1 contamination in maize samples collected from different geographical regions of India - a multicentre study. Food Addit Contam 1997; 14(2):151-156.
30. Peng T, Liu Z-m, Liu T-W, Li I-Q, Peng M-H, Qin X, Yan L-N, Liang R-X, Wei Z-L, Wang L-W, Wang Q, Shen H-M, Ong C-N, Regina M: Associated factors in modulating aflatoxin b1-albumin adduct level in three Chinese populations. Dig Dis Sci 2005; 50(3):525-532.
31. Chelule PK, Gqaleni N, Dutton MF, Chuturgoon AA: Exposure of rural and urban populations in KwaZulu Natal, South Africa, to fumonisin B(1) in maize. Environ Health Perspect 2001; 109(3):253-256.
32. Olubuide IO, Maxwell SM, Akinyinka OO, Hart CA, Neal GE, Hendrickse RG: HBsAg and aflatoxins in sera of rural (igbd-ora) and urban (Ibadan) populations in Nigeria. Afr J Med Sci 1993; 22(4):77-80.
33. Bhat RV: Aflatoxin and liver injury. Trop Gastroenterol 1996; 17(3):153-160.
34. Sayed HA, El Ayyat A, El Dusoki H, Zoheiry M, Mohamed S, Hassan M, El Assaly N Awad A, El Ansary M, Saad A, El Karim AA: A cross section study of hepatitis B,C, some trace element, heavy metals, aflatoxin B1 and schistosomiasis in a rural population, Egypt. J Egypt Public Health Assoc 2005; 80(3-4):355-388.
35. De Flora S, Hietanen E, Bartsch H: Enhanced metabolic activation of chemical hepatocarcinogens in woodchucks infected with hepatitis B virus. Carcinogenesis 1989; 10:1099-1106.
36. Reddy RV, Sharma RP: Effects of aflatoxin B1 on murine lymphocytic functions. Toxicology 1989; 54:31-44.
37. Cusumano V, Rossano F, Merendino RA, et al: Immunobiological activities of mould products: functional impairment of human monocytes exposed to aflatoxin B1. Res Microbiol 1996; 147:385-391.
38. Barraud L, Guerret S, Chevallier M, et al: Enhanced duck hepatitisB virus gene expression following aflatoxin B1 exposure. Hepatology 1999; 29:1317-1323.
39. Omer RE, Kuijsten A, Kadaru AM, Kok FJ, Idris MO, El Khidir IM, van't Veer P: Population-attributable risk of dietary aflatoxins and hepatitis B virus infection with respect to hepatocellular carcinoma. Nutr Cancer 2004; 48(1):15-21.
40. Wang JS, Qian GS, Zarba A, et al: Temporal patterns of aflatoxinalbumin adducts in hepatitis B surface antigenpositive and antigennegative residents of Daxin, Qidong County, People's Republic of China. Cancer Epidemiol Biomarkers Prev 1996; 5:253-261.
41. Naidu NR, Sehgal S, Bhaskar KV, Aikat BK: Cystic disease of the liver following prenatal and perinatal exposure to aflatoxin B1 in rats. J Gastroenterol Hepatol 1991; 6(4):359-362.
42. Barton CC, Hill DA, Yee SB, Barton EX, Ganey PE, Roth RA: Bacterial lipopolysaccharide exposure augments aflatoxin B(1)-induced liver injury. Toxicol Sci 2000; 55:444-452.
43. Sell S, Xu KL, Huff WE, Kabena LF, Harvery RB, Dunsford HA: Aflatoxin exposure produces serum alphafetoprotein elevations and marked oval cell proliferation in young male Peking ducklings. Pathology 1998; 30(1):34-39.