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Volumn 28, Issue 4, 2008, Pages 619-626

Pharmacogenetics-Guided Dose Modifications of Antidepressants

Author keywords

[No Author keywords available]

Indexed keywords

AMFEBUTAMONE; AMITRIPTYLINE; ANTIDEPRESSANT AGENT; CITALOPRAM; CLOMIPRAMINE; CYTOCHROME P450 2C19; CYTOCHROME P450 2D6; DESIPRAMINE; DOXEPIN; IMIPRAMINE; MAPROTILINE; MIANSERIN; NEFAZODONE; NORTRIPTYLINE; PAROXETINE; SERTRALINE; TRAZODONE; TRIMIPRAMINE; VENLAFAXINE;

EID: 57049097080     PISSN: 02722712     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cll.2008.05.006     Document Type: Review
Times cited : (39)

References (34)
  • 1
    • 3142519666 scopus 로고    scopus 로고
    • Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response
    • Kirchheiner J., Nickchen K., Bauer M., et al. Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response. Mol Psychiatry 9 5 (2004) 442-473
    • (2004) Mol Psychiatry , vol.9 , Issue.5 , pp. 442-473
    • Kirchheiner, J.1    Nickchen, K.2    Bauer, M.3
  • 2
    • 0034894010 scopus 로고    scopus 로고
    • CYP2D6 and CYP2C19 genotype-based dose recommendations for antidepressants: a first step towards subpopulation-specific dosages
    • Kirchheiner J., Brosen K., Dahl M.L., et al. CYP2D6 and CYP2C19 genotype-based dose recommendations for antidepressants: a first step towards subpopulation-specific dosages. Acta Psychiatr Scand 104 3 (2001) 173-192
    • (2001) Acta Psychiatr Scand , vol.104 , Issue.3 , pp. 173-192
    • Kirchheiner, J.1    Brosen, K.2    Dahl, M.L.3
  • 3
    • 0036009619 scopus 로고    scopus 로고
    • The thiopurine S-methyltransferase gene locus-implications for clinical pharmacogenomics
    • McLeod H.L., and Siva C. The thiopurine S-methyltransferase gene locus-implications for clinical pharmacogenomics. Pharmacogenomics 3 1 (2002) 89-98
    • (2002) Pharmacogenomics , vol.3 , Issue.1 , pp. 89-98
    • McLeod, H.L.1    Siva, C.2
  • 4
    • 34047221919 scopus 로고    scopus 로고
    • Prevalence of patients using drugs metabolized by cytochrome P450 2D6 in different populations: a cross-sectional study
    • Mulder H., Heerdink E.R., van Iersel E.E., et al. Prevalence of patients using drugs metabolized by cytochrome P450 2D6 in different populations: a cross-sectional study. Ann Pharmacother 41 3 (2007) 408-413
    • (2007) Ann Pharmacother , vol.41 , Issue.3 , pp. 408-413
    • Mulder, H.1    Heerdink, E.R.2    van Iersel, E.E.3
  • 5
    • 0024359574 scopus 로고
    • Clinical significance of the sparteine/debrisoquine oxidation polymorphism
    • Brøsen K., and Gram L.F. Clinical significance of the sparteine/debrisoquine oxidation polymorphism. Eur J Clin Pharmacol 36 6 (1989) 537-547
    • (1989) Eur J Clin Pharmacol , vol.36 , Issue.6 , pp. 537-547
    • Brøsen, K.1    Gram, L.F.2
  • 6
    • 12944281041 scopus 로고    scopus 로고
    • Amitriptyline or not, that is the question: pharmacogenetic testing of CYP2D6 and CYP2C19 identifies patients with low or high risk for side effects in amitriptyline therapy
    • Steimer W., Zopf K., von Amelunxen S., et al. Amitriptyline or not, that is the question: pharmacogenetic testing of CYP2D6 and CYP2C19 identifies patients with low or high risk for side effects in amitriptyline therapy. Clin Chem 51 2 (2005) 376-385
    • (2005) Clin Chem , vol.51 , Issue.2 , pp. 376-385
    • Steimer, W.1    Zopf, K.2    von Amelunxen, S.3
  • 7
    • 0036796048 scopus 로고    scopus 로고
    • The impact of the CYP2D6 polymorphism on haloperidol pharmacokinetics and on the outcome of haloperidol treatment
    • Brockmoller J., Kirchheiner J., Schmider J., et al. The impact of the CYP2D6 polymorphism on haloperidol pharmacokinetics and on the outcome of haloperidol treatment. Clin Pharmacol Ther 72 4 (2002) 438-452
    • (2002) Clin Pharmacol Ther , vol.72 , Issue.4 , pp. 438-452
    • Brockmoller, J.1    Kirchheiner, J.2    Schmider, J.3
  • 8
    • 37349045083 scopus 로고    scopus 로고
    • Allelic variants in the CYP2C9 and VKORC1 loci and interindividual variability in the anticoagulant dose effect of warfarin in Italians
    • Borgiani P., Ciccacci C., Forte V., et al. Allelic variants in the CYP2C9 and VKORC1 loci and interindividual variability in the anticoagulant dose effect of warfarin in Italians. Pharmacogenomics 8 11 (2007) 1545-1550
    • (2007) Pharmacogenomics , vol.8 , Issue.11 , pp. 1545-1550
    • Borgiani, P.1    Ciccacci, C.2    Forte, V.3
  • 9
    • 34248580622 scopus 로고    scopus 로고
    • Genotypes of vitamin K epoxide reductase, gamma-glutamyl carboxylase, and cytochrome P450 2C9 as determinants of daily warfarin dose in Japanese patients
    • Kimura R., Miyashita K., Kokubo Y., et al. Genotypes of vitamin K epoxide reductase, gamma-glutamyl carboxylase, and cytochrome P450 2C9 as determinants of daily warfarin dose in Japanese patients. Thromb Res 120 2 (2007) 181-186
    • (2007) Thromb Res , vol.120 , Issue.2 , pp. 181-186
    • Kimura, R.1    Miyashita, K.2    Kokubo, Y.3
  • 10
    • 33646479231 scopus 로고    scopus 로고
    • CYP2C9 polymorphism and warfarin sensitivity in Taiwan Chinese
    • Chern H.D., Ueng T.H., Fu Y.P., et al. CYP2C9 polymorphism and warfarin sensitivity in Taiwan Chinese. Clin Chim Acta 367 1-2 (2006) 108-113
    • (2006) Clin Chim Acta , vol.367 , Issue.1-2 , pp. 108-113
    • Chern, H.D.1    Ueng, T.H.2    Fu, Y.P.3
  • 11
    • 23044440450 scopus 로고    scopus 로고
    • The impact of CYP2C9 and VKORC1 genetic polymorphism and patient characteristics upon warfarin dose requirements: proposal for a new dosing regimen
    • Sconce E.A., Khan T.I., Wynne H.A., et al. The impact of CYP2C9 and VKORC1 genetic polymorphism and patient characteristics upon warfarin dose requirements: proposal for a new dosing regimen. Blood 106 7 (2005) 2329-2333
    • (2005) Blood , vol.106 , Issue.7 , pp. 2329-2333
    • Sconce, E.A.1    Khan, T.I.2    Wynne, H.A.3
  • 12
    • 4143065736 scopus 로고    scopus 로고
    • Relative impact of covariates in prescribing warfarin according to CYP2C9 genotype
    • Hillman M.A., Wilke R.A., Caldwell M.D., et al. Relative impact of covariates in prescribing warfarin according to CYP2C9 genotype. Pharmacogenetics 14 8 (2004) 539-547
    • (2004) Pharmacogenetics , vol.14 , Issue.8 , pp. 539-547
    • Hillman, M.A.1    Wilke, R.A.2    Caldwell, M.D.3
  • 13
    • 1542346414 scopus 로고    scopus 로고
    • Contribution of age, body size, and CYP2C9 genotype to anticoagulant response to warfarin
    • Kamali F., Khan T.I., King B.P., et al. Contribution of age, body size, and CYP2C9 genotype to anticoagulant response to warfarin. Clin Pharmacol Ther 75 3 (2004) 204-212
    • (2004) Clin Pharmacol Ther , vol.75 , Issue.3 , pp. 204-212
    • Kamali, F.1    Khan, T.I.2    King, B.P.3
  • 14
    • 0036047459 scopus 로고    scopus 로고
    • World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Unipolar Depressive Disorders, Part 1: acute and continuation treatment of major depressive disorder
    • Bauer M., Whybrow P.C., Angst J., et al. World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Unipolar Depressive Disorders, Part 1: acute and continuation treatment of major depressive disorder. World J Biol Psychiatry 3 1 (2002) 5-43
    • (2002) World J Biol Psychiatry , vol.3 , Issue.1 , pp. 5-43
    • Bauer, M.1    Whybrow, P.C.2    Angst, J.3
  • 15
    • 0022692071 scopus 로고
    • Amitriptyline pharmacokinetics and clinical response: II. Metabolic polymorphism assessed by hydroxylation of debrisoquine and mephenytoin
    • Baumann P., Jonzier Perey M., Koeb L., et al. Amitriptyline pharmacokinetics and clinical response: II. Metabolic polymorphism assessed by hydroxylation of debrisoquine and mephenytoin. Int Clin Psychopharmacol 1 2 (1986) 102-112
    • (1986) Int Clin Psychopharmacol , vol.1 , Issue.2 , pp. 102-112
    • Baumann, P.1    Jonzier Perey, M.2    Koeb, L.3
  • 16
    • 0034751517 scopus 로고    scopus 로고
    • Inhibition of cytochrome P4502D6 activity with paroxetine normalizes the ultrarapid metabolizer phenotype as measured by nortriptyline pharmacokinetics and the debrisoquin test
    • Laine K., Tybring G., Hartter S., et al. Inhibition of cytochrome P4502D6 activity with paroxetine normalizes the ultrarapid metabolizer phenotype as measured by nortriptyline pharmacokinetics and the debrisoquin test. Clin Pharmacol Ther 70 4 (2001) 327-335
    • (2001) Clin Pharmacol Ther , vol.70 , Issue.4 , pp. 327-335
    • Laine, K.1    Tybring, G.2    Hartter, S.3
  • 17
    • 0036021208 scopus 로고    scopus 로고
    • CYP2D6 inhibition by selective serotonin reuptake inhibitors: analysis of achievable steady-state plasma concentrations and the effect of ultrarapid metabolism at CYP2D6
    • Lam Y.W., Gaedigk A., Ereshefsky L., et al. CYP2D6 inhibition by selective serotonin reuptake inhibitors: analysis of achievable steady-state plasma concentrations and the effect of ultrarapid metabolism at CYP2D6. Pharmacotherapy 22 8 (2002) 1001-1006
    • (2002) Pharmacotherapy , vol.22 , Issue.8 , pp. 1001-1006
    • Lam, Y.W.1    Gaedigk, A.2    Ereshefsky, L.3
  • 18
    • 0029860967 scopus 로고    scopus 로고
    • Disposition of fluvoxamine in humans is determined by the polymorphic CYP2D6 and also by the CYP1A2 activity
    • Carrillo J.A., Dahl M.L., Svensson J.O., et al. Disposition of fluvoxamine in humans is determined by the polymorphic CYP2D6 and also by the CYP1A2 activity. Clin Pharmacol Ther 60 2 (1996) 183-190
    • (1996) Clin Pharmacol Ther , vol.60 , Issue.2 , pp. 183-190
    • Carrillo, J.A.1    Dahl, M.L.2    Svensson, J.O.3
  • 19
    • 0030957166 scopus 로고    scopus 로고
    • Relationship between fluvoxamine pharmacokinetics and CYP2D6/CYP2C19 phenotype polymorphisms
    • Spigset O., Granberg K., Hagg S., et al. Relationship between fluvoxamine pharmacokinetics and CYP2D6/CYP2C19 phenotype polymorphisms. Eur J Clin Pharmacol 52 2 (1997) 129-133
    • (1997) Eur J Clin Pharmacol , vol.52 , Issue.2 , pp. 129-133
    • Spigset, O.1    Granberg, K.2    Hagg, S.3
  • 20
    • 0031915975 scopus 로고    scopus 로고
    • Non-linear fluvoxamine disposition
    • Spigset O., Granberg K., Hagg S., et al. Non-linear fluvoxamine disposition. Br J Clin Pharmacol 45 3 (1998) 257-263
    • (1998) Br J Clin Pharmacol , vol.45 , Issue.3 , pp. 257-263
    • Spigset, O.1    Granberg, K.2    Hagg, S.3
  • 21
    • 0026606822 scopus 로고
    • The relationship between paroxetine and the sparteine oxidation polymorphism
    • Sindrup S.H., Brøsen K., Gram L.F., et al. The relationship between paroxetine and the sparteine oxidation polymorphism. Clin Pharmacol Ther 51 3 (1992) 278-287
    • (1992) Clin Pharmacol Ther , vol.51 , Issue.3 , pp. 278-287
    • Sindrup, S.H.1    Brøsen, K.2    Gram, L.F.3
  • 22
    • 0029016328 scopus 로고
    • Moclobemide, a substrate of CYP2C19 and an inhibitor of CYP2C19, CYP2D6, and CYP1A2: a panel study
    • Gram L.F., Guentert T.W., Grange S., et al. Moclobemide, a substrate of CYP2C19 and an inhibitor of CYP2C19, CYP2D6, and CYP1A2: a panel study. Clin Pharmacol Ther 57 6 (1995) 670-677
    • (1995) Clin Pharmacol Ther , vol.57 , Issue.6 , pp. 670-677
    • Gram, L.F.1    Guentert, T.W.2    Grange, S.3
  • 23
    • 0034923234 scopus 로고    scopus 로고
    • Pharmacokinetics of sertraline in relation to genetic polymorphism of CYP2C19
    • Wang J.H., Liu Z.Q., Wang W., et al. Pharmacokinetics of sertraline in relation to genetic polymorphism of CYP2C19. Clin Pharmacol Ther 70 1 (2001) 42-47
    • (2001) Clin Pharmacol Ther , vol.70 , Issue.1 , pp. 42-47
    • Wang, J.H.1    Liu, Z.Q.2    Wang, W.3
  • 24
    • 0027472058 scopus 로고
    • Pharmacokinetics of citalopram in relation to the sparteine and the mephenytoin oxidation polymorphisms
    • Sindrup S.H., Brøsen K., Hansen M.G., et al. Pharmacokinetics of citalopram in relation to the sparteine and the mephenytoin oxidation polymorphisms. Ther Drug Monit 15 1 (1993) 11-17
    • (1993) Ther Drug Monit , vol.15 , Issue.1 , pp. 11-17
    • Sindrup, S.H.1    Brøsen, K.2    Hansen, M.G.3
  • 26
    • 0032587641 scopus 로고    scopus 로고
    • *10 genotype on venlafaxine pharmacokinetics in healthy adult volunteers
    • *10 genotype on venlafaxine pharmacokinetics in healthy adult volunteers. Br J Clin Pharmacol 47 4 (1999) 450-453
    • (1999) Br J Clin Pharmacol , vol.47 , Issue.4 , pp. 450-453
    • Fukuda, T.1    Yamamoto, I.2    Nishida, Y.3
  • 27
    • 0034114843 scopus 로고    scopus 로고
    • The impact of the CYP2D6 and CYP2C19 genotypes on venlafaxine pharmacokinetics in a Japanese population
    • Fukuda T., Nishida Y., Zhou Q., et al. The impact of the CYP2D6 and CYP2C19 genotypes on venlafaxine pharmacokinetics in a Japanese population. Eur J Clin Pharmacol 56 (2000) 175-180
    • (2000) Eur J Clin Pharmacol , vol.56 , pp. 175-180
    • Fukuda, T.1    Nishida, Y.2    Zhou, Q.3
  • 28
    • 0030045095 scopus 로고    scopus 로고
    • Venlafaxine oxidation in vitro is catalysed by CYP2D6
    • Otton S.V., Ball S.E., Cheung S.W., et al. Venlafaxine oxidation in vitro is catalysed by CYP2D6. Br J Clin Pharmacol 41 2 (1996) 149-156
    • (1996) Br J Clin Pharmacol , vol.41 , Issue.2 , pp. 149-156
    • Otton, S.V.1    Ball, S.E.2    Cheung, S.W.3
  • 29
    • 0034108957 scopus 로고    scopus 로고
    • Venlafaxine serum levels and CYP2D6 genotype
    • Veefkind A.H., Haffmans P.M., and Hoencamp E. Venlafaxine serum levels and CYP2D6 genotype. Ther Drug Monit 22 2 (2000) 202-208
    • (2000) Ther Drug Monit , vol.22 , Issue.2 , pp. 202-208
    • Veefkind, A.H.1    Haffmans, P.M.2    Hoencamp, E.3
  • 30
    • 33748363505 scopus 로고    scopus 로고
    • CYP2D6 polymorphism and clinical effect of the antidepressant venlafaxine
    • Shams M.E., Arneth B., Hiemke C., et al. CYP2D6 polymorphism and clinical effect of the antidepressant venlafaxine. J Clin Pharm Ther 31 5 (2006) 493-502
    • (2006) J Clin Pharm Ther , vol.31 , Issue.5 , pp. 493-502
    • Shams, M.E.1    Arneth, B.2    Hiemke, C.3
  • 31
    • 0032847231 scopus 로고    scopus 로고
    • Influence of CYP2D6 activity on the disposition and cardiovascular toxicity of the antidepressant agent venlafaxine in humans
    • Lessard E., Yessine M., Hamelin B., et al. Influence of CYP2D6 activity on the disposition and cardiovascular toxicity of the antidepressant agent venlafaxine in humans. Pharmacogenetics 9 (1999) 435-443
    • (1999) Pharmacogenetics , vol.9 , pp. 435-443
    • Lessard, E.1    Yessine, M.2    Hamelin, B.3
  • 32
    • 2042512985 scopus 로고    scopus 로고
    • CYP2D6 genotype: impact on adverse effects and nonresponse during treatment with antidepressants-a pilot study
    • Rau T., Wohlleben G., Wuttke H., et al. CYP2D6 genotype: impact on adverse effects and nonresponse during treatment with antidepressants-a pilot study. Clin Pharmacol Ther 75 5 (2004) 386-393
    • (2004) Clin Pharmacol Ther , vol.75 , Issue.5 , pp. 386-393
    • Rau, T.1    Wohlleben, G.2    Wuttke, H.3
  • 33
    • 19244365359 scopus 로고    scopus 로고
    • Impact of polymorphisms of cytochrome-P450 isoenzymes 2C9, 2C19 and 2D6 on plasma concentrations and clinical effects of antidepressants in a naturalistic clinical setting
    • Grasmader K., Verwohlt P.L., Rietschel M., et al. Impact of polymorphisms of cytochrome-P450 isoenzymes 2C9, 2C19 and 2D6 on plasma concentrations and clinical effects of antidepressants in a naturalistic clinical setting. Eur J Clin Pharmacol 60 5 (2004) 329-336
    • (2004) Eur J Clin Pharmacol , vol.60 , Issue.5 , pp. 329-336
    • Grasmader, K.1    Verwohlt, P.L.2    Rietschel, M.3
  • 34
    • 1242269894 scopus 로고    scopus 로고
    • Increased incidence of CYP2D6 gene duplication in patients with persistent mood disorders: ultrarapid metabolism of antidepressants as a cause of nonresponse. A pilot study
    • Kawanishi C., Lundgren S., Agren H., et al. Increased incidence of CYP2D6 gene duplication in patients with persistent mood disorders: ultrarapid metabolism of antidepressants as a cause of nonresponse. A pilot study. Eur J Clin Pharmacol 59 11 (2004) 803-807
    • (2004) Eur J Clin Pharmacol , vol.59 , Issue.11 , pp. 803-807
    • Kawanishi, C.1    Lundgren, S.2    Agren, H.3


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