The age-related decrease in catecholamine sensitivity is mediated by ß1-adrenergic receptors linked to a decrease in adenylate cyclase activity in ventricular myocytes from male Fischer 344 rats

Mechanisms of Ageing and Development

Volumn 129, Issue 12, 2008, Pages 735-744

  Farrell, Spring R ^a   Howlett, Susan E ^a,b  

^a DALHOUSIE UNIVERSITY   (Canada)

^b DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Adrenergic receptors; Adenylate cyclase; Aging; Ca2+ transient; cAMP

Indexed keywords

ADENYLATE CYCLASE; BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BUCLADESINE; CALCIUM; CATECHOLAMINE; CYCLIC AMP; DOBUTAMINE; FORSKOLIN; PHOSPHODIESTERASE INHIBITOR;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CALCIUM CELL LEVEL; CELL ISOLATION; CONTROLLED STUDY; ENZYME ACTIVITY; FISCHER 344 RAT; HEART CONTRACTION; HEART MUSCLE CELL; INOTROPISM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ADENYLATE CYCLASE; ADRENERGIC BETA-AGONISTS; AGING; ALBUTEROL; ANIMALS; BUCLADESINE; CALCIUM SIGNALING; CATECHOLAMINES; CYCLIC AMP; DOBUTAMINE; ELECTRIC STIMULATION; FORSKOLIN; MALE; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; RATS; RATS, INBRED F344; RECEPTORS, ADRENERGIC, BETA-1;

RATTUS;

EID: 56949086532     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2008.09.017     Document Type: Article

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