An IL-12 DNA vaccine co-expressing Yersinia pestis antigens protects against pneumonic plague

Vaccine

Volumn 27, Issue 1, 2009, Pages 80-87

  Yamanaka, Hitoki ^a   Hoyt, Teri ^a   Bowen, Richard ^b   Yang, Xinghong ^a   Crist, Kathryn ^a   Golden, Sarah ^a   Maddaloni, Massimo ^a   Pascual, David W ^a  

^a MONTANA STATE UNIVERSITY   (United States)

^b Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

DNA vaccine; IL 12; Pneumonic plague

Indexed keywords

CAPSULAR F1 ANTIGEN; CHOLERA TOXIN; DNA VACCINE; GAMMA INTERFERON; HYBRID PROTEIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN G2B; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 12 CAPSULAR F1 ANTIGEN DNA VACCINE; INTERLEUKIN 12 VIRULENCE ANTIGEN DNA VACCINE; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; VIRULENCE ANTIGEN; VIRUS ANTIGEN;

293A CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; B LYMPHOCYTE; BOOSTER IMMUNIZATION; CELL LINE; CONTROLLED STUDY; CYTOKINE RELEASE; DNA IMMUNIZATION; DRUG EFFICACY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME LINKED IMMUNOSPOT ASSAY; FEMALE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOGENICITY; LD 50; LYMPHOID ORGAN; MOUSE; MUCOSAL IMMUNITY; NONHUMAN; PLAGUE; PLASMID; PNEUMONIC PLAGUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVACCINATION; SPLEEN CELL; YERSINIA PESTIS;

ANIMALS; ANTIGENS, BACTERIAL; CELL LINE; CYTOKINES; FEMALE; INTERLEUKIN-12; MICE; MICE, INBRED BALB C; PLAGUE; PLAGUE VACCINE; PLASMIDS; SPLEEN; VACCINES, DNA; YERSINIA PESTIS;

EID: 56949084010     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2008.10.021     Document Type: Article

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