Spatial confinement of ultrasonic force fields in microfluidic channels

Ultrasonics

Volumn 49, Issue 1, 2009, Pages 112-119

  Manneberg, Otto ^a   Melker Hagsater S ^b   Svennebring, Jessica ^a   Hertz, Hans M ^a   Kutter, Jörg P ^b   Bruus, Henrik ^b   Wiklund, Martin ^a  

^a ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

Acoustic radiation force; Cell handling; Microfluidic chip; Particle image velocimetry; Spatial confinement; Ultrasonic manipulation

Indexed keywords

ACOUSTIC FIELDS; ACOUSTIC WAVES; ACOUSTICS; CROSSTALK; FLOW VISUALIZATION; FLUIDIC DEVICES; PROBABILITY DENSITY FUNCTION; THICKNESS MEASUREMENT; ULTRASONICS; VELOCIMETERS; VELOCITY MEASUREMENT;

ACOUSTIC RADIATION FORCE; CELL HANDLING; MICROFLUIDIC CHIP; PARTICLE IMAGE VELOCIMETRY; SPATIAL CONFINEMENT; ULTRASONIC MANIPULATION;

BIOCHIPS;

ARTICLE; CELL SEPARATION; INSTRUMENTATION; MECHANICAL STRESS; METHODOLOGY; MICROFLUIDIC ANALYSIS; MICROMANIPULATION; ULTRASOUND;

CELL SEPARATION; MICROFLUIDIC ANALYTICAL TECHNIQUES; MICROMANIPULATION; SONICATION; STRESS, MECHANICAL;

EID: 56949083339     PISSN: 0041624X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ultras.2008.06.012     Document Type: Article

References (28)

1. Wiklund M., and Hertz H.M. Ultrasonic enhancement of bead-based bioaffinity assays. Lab Chip 6 (2006) 1279-1292
2. Laurell T., Petersson F., and Nilsson A. Chip integrated strategies for acoustic separation and manipulation of cells and particles. Chem. Soc. Rev. 36 (2007) 492-506
3. O. Manneberg et al., Elementary manipulation functions for gentle and long-term handling of cells in microchannels by ultrasonic standing waves, Proc. of Nanotech-Montreux 2006, Montreux, Switzerland, 2006.
4. Müller T., Pfennig A., Klein P., Gradl G., Jäger M., and Schnelle T. The potential of dielectrophoresis for single-cell experiments. IEEE Eng. Med. Biol. 22 (2003) 51-61
5. Enger J., Goksör M., Ramser K., Hagberg P., and Hanstorp D. Optical tweezers applied to a microfluidic system. Lab Chip 4 (2004) 196-200
6. Wiklund M., Günther C., Lemor R., Jäger M., Fuhr G., and Hertz H.M. Ultrasonic standing wave manipulation technology integrated into a dielectrophoretic chip. Lab Chip 6 (2006) 1537-1544
7. Hultström J., Manneberg O., Dopf K., Hertz H.M., Brismar H., and Wiklund M. Proliferation and viability of adherent cells manipulated by standing-wave ultrasound in a microfluidic chip. Ultrasound Med. Biol. 33 (2007) 145-151
8. Svennebring J., Manneberg O., and Wiklund M. Temperature regulation during ultrasonic manipulation for long-term cell handling in a microfluidic chip. J. Micromech. Microeng. 17 (2007) 2469-2474
9. Hawkes J.J., and Coakley W.T. Force field particle filter, combining ultrasound standing waves and laminar flow. Sens. Actuator B-Chem. 75 (2001) 213-222
10. Harris N.R., Hill M., Beeby S., Shen Y., White N.M., Hawkes J.J., and Coakley W.T. A silicon microfluidic ultrasonic separator. Sens. Actuator B-Chem. 95 (2003) 425-434
11. Yasuda K. Non-destructive non-contact handling method for biomaterials in micro-chamber by ultrasound. Sens. Actuator B-Chem. 64 (2000) 128-135
12. Kapishnikov S., Kantsler V., and Steinberg V. Continuous particle size separation and size sorting using ultrasound in a microchannel. J. Stat. Mech. P01012 (2006) 1-15
13. Haake A., and Dual J. Positioning of small particles by an ultrasound field excited by surface waves. Ultrasonics 42 (2004) 75-80
14. Lilliehorn T., Simu U., Nilsson M., Almqvist M., Stepinski T., Laurell T., Nilsson J., and Johansson S. Trapping of microparticles in the near field of an ultrasonic transducer. Ultrasonics 43 (2005) 293-303
15. Lilliehorn T., Nilsson M., Simu U., Johansson S., Almqvist M., Nilsson J., and Laurell T. Dynamic arraying of microbeads for bioassays in microfluidic channels. Sens. Actuator B-Chem. 106 (2005) 851-858
16. Evander M., Johansson L., Lilliehorn T., Piskur J., Lindvall M., Johansson S., Almqvist M., Laurell T., and Nilsson J. Noninvasive acoustic cell trapping in a microfluidic perfusion system for online bioassays. Anal. Chem. 79 (2007) 2984-2991
17. Santiago J.G., Wereley S.T., Meinhart C.D., Beebe D.J., and Adrian R.J. A particle image velocimetry system for microfluidics. Exp. Fluids 25 (1998) 316-319
18. Hagsäter S.M., Glasdam Jensen T., Bruus H., and Kutter J.P. Acoustic resonances in microfluidic chips: Full-image micro-PIV experiments and numerical simulations. Lab Chip 7 (2007) 1336-1344
19. Gröschl M. Ultrasonic separation of suspended particles - Part I: fundamentals. Acta Acustica 84 (1998) 432-447
20. Gor'kov L.P. On the forces acting on a small particle in an acoustic field in an ideal fluid. Sov. Phys. Doklady 6 (1962) 773-775
21. M. Wiklund, Ultrasonic enrichment of microparticles in bioaffinity assays, PhD Thesis, Royal Institute of Technology (2004) ISBN 91-7283-723-3.
22. Oberti S., Neild A., and Dual J. Manipulation of micrometer sized particles within a micromachined fluidic device to form two-dimensional patterns using ultrasound. J. Acoust. Soc. Am. 121 (2007) 778-785
23. Bruus H. Theoretical Microfluidics (2007), Oxford University Press, Oxford
24. Zarembo L.K. Acoustic streaming. In: Rozenberg L.D. (Ed). High-Intensity Ultrasonic Fields (1971), Plenum Press, New York 138-199 vol. 85, part 3
25. Hagsäter S.M., Westergaard C.H., Bruus H., and Kutter J.P. Investigations on LED illumination for micro-PIV including a novel front-lit configuration. Exp. Fluids 44 (2008) 211-219
26. Hill M. The selection of layer thicknesses to control acoustic radiation force profiles in layered resonators. J. Acoust. Soc. Am. 114 (2003) 2654-2661
27. Wiklund M., Toivonen J., Tirri M., Hänninen P., and Hertz H.M. Ultrasonic enrichment of microspheres for ultrasensitive biomedical analysis in confocal laser-scanning fluorescence detection. J. Appl. Phys. 96 (2004) 1242-1248
28. Hagsäter S.M., Lenshof A., Skafte-Pedersen P., Kutter J.P., Laurell T., and Bruus H. Acoustic resonances in straight micro channels: beyond the 1D-approximation. Lab Chip (2008) doi: 10.1039/b801028e