Proteomic analysis of conditioned media from glucose responsive and glucose non-responsive phenotypes reveals a panel of secreted proteins associated with beta cell dysfunction

Electrophoresis

Volumn 29, Issue 20, 2008, Pages 4141-4149

  Dowling, Paul ^a   Shields, William ^a   Rani, Sweta ^a   Meleady, Paula ^a   Henry, Michael ^a   Jeppesen, Per ^b   O'Driscoll, Lorraine ^a   Clynes, Martin ^a  

^a DUBLIN CITY UNIVERSITY   (Ireland)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Beta cell; Biomarkers; Diabetes; Difference gel electrophoresis; MIN 6

Indexed keywords

CELL CULTURE; CELLS; ELECTROPHORESIS; MASS SPECTROMETRY; PROTEINS;

BETA CELL; CELL DYSFUNCTION; CONDITIONED MEDIUM; DIFFERENCE GEL ELECTROPHORESIS; GLUCOSE-RESPONSIVE; GLUCOSE-STIMULATED INSULIN SECRETIONS; MIN-6; MODELLING SYSTEMS; PROTEIN MARKERS; PROTEOMIC ANALYSIS;

GLUCOSE;

CELL PROTEIN; GLUCOSE; INSULIN; PREALBUMIN; SECRETOGRANIN II; SECRETOGRANIN III; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOGENESIS; CELL STIMULATION; CONTROLLED STUDY; CULTURE MEDIUM; INSULIN RELEASE; MASS SPECTROMETRY; MOUSE; NONHUMAN; PANCREAS ISLET CELL FUNCTION; PANCREAS ISLET DISEASE; PHENOTYPE; PROTEIN ANALYSIS; PROTEIN SECRETION; PROTEOMICS; STIMULUS RESPONSE; TWO DIMENSIONAL GEL ELECTROPHORESIS;

EID: 56849124888     PISSN: 01730835     EISSN: 15222683     Source Type: Journal    
DOI: 10.1002/elps.200800152     Document Type: Article

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