Uncertainties in internal doses calculated for mayak workers - A study of 63 cases

Radiation Protection Dosimetry

Volumn 131, Issue 3, 2008, Pages 316-330

  Miller, Guthier ^a   Guilmette, R ^a   Bertelli, L ^a   Waters, T ^a   Romanov, S A ^b   Zaytseva, Y V ^b  

^a LOS ALAMOS NATIONAL LABORATORY   (United States)

^b SOUTH URAL STATE UNIVERSITY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

PLUTONIUM 239;

ADULT; ARTICLE; AUTOPSY; BAYES THEOREM; CASE STUDY; CONTROLLED STUDY; DATA ANALYSIS; DATA EXTRACTION; DOSIMETRY; FEMALE; HUMAN; HUMAN TISSUE; MALE; MATHEMATICAL MODEL; OCCUPATIONAL EXPOSURE; POISSON DISTRIBUTION; QUANTITATIVE ANALYSIS; RADIATION DOSE; RADIATION EXPOSURE; RADIATION INJURY; RADIATION MEASUREMENT; UNCERTAINTY; URINALYSIS; WORKER;

ADMINISTRATION, INHALATION; AIR POLLUTANTS, OCCUPATIONAL; AIR POLLUTANTS, RADIOACTIVE; ALGORITHMS; AUTOPSY; BAYES THEOREM; BIOLOGICAL ASSAY; BODY BURDEN; HUMANS; MODELS, STATISTICAL; OCCUPATIONAL EXPOSURE; PLUTONIUM; RADIOMETRY; TISSUE DISTRIBUTION; UNCERTAINTY;

EID: 56849096308     PISSN: 01448420     EISSN: None     Source Type: Journal    
DOI: 10.1093/rpd/ncn181     Document Type: Article

References (26)

1. Suslova, K. G., Filipy, R E., Khokhryakov, V. F., Romanov, S. A. and Kathern, R. L. Comparison of the dosimetry registry of the Mayak Industrial Association and the United States Transuranium and Uranium Registries: A preliminary report. Radiat. Prot. Dosim. 67, 13-22 (1996).
2. Khokhryakov, V. F., Kudryavtseva, T. I., Chernikov, V. I., Suslova, K. G., Orlova, I. A. and Filipy, R. E. A scintillation method for determination of actinide alpha-activity in samples. J. Radioanal. Nucl. Chem. 234, 293-295 (1998).
3. Romanov, S. A., Vasilenko, E. K. and Khokhryakov, J. P. Studies on the Mayak Nuclear Workers: Dosimetry. Radiat. Environ. Biophys. 41 23-28 (2002).
4. Sayapina, R. Y., Voronin, P. F. and Badyin, V. I. et al. Materials to assess plutonium aerosol size distributions and inhalation intake amount Moscow Biophysics Institute report (in Russian), Moscow, (1969).
5. Zaytseva, Y. V., Tretyakov, F. D., Romanov, S. A., Miller, G, Bertelli, L and Guilmette, R. A. Use of air monitoring and experimental aerosol data for intake assessment for Mayak Plutonium Workers. Radiat. Prot. Dosim. 127, 535-539 (2007). doi:10.1093/rpd/ncm413.
6. Khokhryakov, V. F., Suslova, K. G., Vadim, V. V., Romanov, S. A., Zoya, S. M., Kudryavtseva, T. I., Filipy, R. E., Miller, S. C. and Krahenbuhl, M. P. The development of the plutonium lung clearance model for exposure estimation of the Mayak Production Association, Nuclear Plant Workers. Health Phys. 82, 425-431 (2002).
7. Miller, G. Statistical modeling of Poisson-lognormal data. Radiat. Prot. Dosim. 124, 155-163 (2007).
8. Miller, G. Analytical approximation of exact Poisson-lognormal likelihood functions. Health Phys. 94, 188-191 (2008).
9. ICRP. Human Respiratory Tract Model for Radiological Protection. International Commission on Radiological Protection Publication 66 (Pergamon Press, Oxford) (1994).
10. Khokhryakov, V. F., Suslova, K. G., Vostrotin, V. V., Romanov, S. A., Eckerman, K. F., Krahenbuhl, M. P. and Miller, S. C. Adaptation of the ICRP Publication 66 respiratory tract model to data on plutonium biokinetics for Mayak Workers. Health Phys. 88, 125-132 (2005).
11. Miller, G, Bertelli, L, Guilmette, R and Little, T. IMPDOS (IMProved DOSimetry and Risk Assessment for Plutonium-Induced Diseases) - internal dosimetry software tools developed for the Mayak Worker Study. Radiat. Prot. Dosim. Accepted for publication 10 June 2008.
12. Leggett, R. W., Eckerman, K. F., Khokhryakov, V. F., Suslova, K. G., Kranhenbuhl, M. P. and Miller, S. C. Mayak Worker Study: An improved biokinetic model for reconstructing doses from internally deposited plutonium. Radiat. Res. 164, 111-122 (2005).
13. Luciani, A and Polig, E. Verification and modification of the ICRP-67 model for plutonium dose calculation. Health Phys. 78, 303-310 (2000).
14. Khokhryakov, V. F., Suslova, K. G., Filipy, R. E., Alldredge, J. R., Aladova, E. E., Glover, S. E. and Vostrotin, V. V. Metabolism and dosimetry of actinide elements in occupationally-exposed personnel of Russia and the United States: A summary progress report. Health Phys. 79, 63-71 (2000).
15. Krahenbuhl, M. P., Bess, J. D., Wilde, J. L., Vostrotin, V. V., Suslova, K. G., Khokhryakov, V. F., Slaughter, D. M. and Miller, S. C. Uncertainties analysis of doses resulting from chronic inhalation of plutonium at the Mayak Production Association. Health Phys. 89, 33-45 (2005).
16. Miller, G. Variability and uncertainty of biokinetic model parameters - the discrete-empirical-Bayes approximation. Radiat. Prot. Dosim. Accepted for publication 10 June 2008.
17. Miller, G, Martz, H. F., Little, T and Guilmette, R. Using exact Poisson likelihood functions in Bayesian interpretation of counting measurements. Health Phys. 83, 512-518 (2002).
18. LANL, Los Alamos Center for Bayesian Methods in Environment, Safety and Health (www.lanl.gov/bayesian), 2007.
19. Good, I. J. Saddle-point methods for the multinomial distribution. Ann. Math. Stat. 28, 861-881 (1957).
20. Miller, G, Martz, H. F., Little, T and Bertelli, L. Bayesian hypothesis testing - use in interpretation of measurements. Health Phys. 94, 248-254 (2008).
21. Miller, G, Martz, H. F., Little, T and Guilmette, R. Bayesian internal dosimetry calculations using Markov chain Monte Carlo. Radiat. Prot. Dosimetry 98, 191-198 (2002).
22. Miller, G. The variance of the number of effects in an epidemiological cohort - the role of dose uncertainty. Open Epidemiol. J. Accepted for publication 9 June 2008.
23. Suslova, K. G., Khokhryakov, V. F., Tokarskaya, Z. B., Nifatov, A. P., Sokolova, A. B., Miller, S. C. and Krahenbuhl, M. P. Modifying effects of health status, physiological and dosimetric factors on extrapulmonary organ distribution and excretion of inhaled plutonium in workers at the Mayak Production Association. Health Phys. 90, 90 (2006).
24. ICRP. Limits for Intakes of Radionuclides by Workers. International Commission on Radiological Protection Publication 30, Part 1 (Pergamon Press, Oxford) (1979).
25. Vasilenko, E. K., Khokhryakov, V. F., Miller, S. C., Fix, J. J., Eckerman, K, Choe, D. O., Gorelov, M, Khokhryakov, V. V. and Knyasev, V. et al. Mayak worder dosimetry study: An overview. Health Phys. 93, 190-206 (2007).
26. Khokhryakov, V. F., Suslova, K. G., Vostrotin, V. V., Romanov, S. A., Eckerman, K. F., Krahenbuhl, M. P. and Miller, S. C. Adaptation of the ICRP Publication 66 respiratory tract model to data on plutonium biokinetics for Mayak Workers. Health Phys. 88, 125-132 (2005).