Maintaining a physiological blood glucose level with 'glucolevel', a combination of four anti-diabetes plants used in the traditional Arab herbal medicine

Evidence-based Complementary and Alternative Medicine

Volumn 5, Issue 4, 2008, Pages 421-428

  Said, Omar ^a,b,c,f   Fulder, Stephen ^a   Khalil, Khaled ^a   Azaizeh, Hassan ^b,c   Kassis, Eli ^e   Saad, Bashar ^b,c,d  

^a Antaki Center for Herbal Medicine Ltd   (Israel)

^b Galilee Society   (Israel)

^c UNIVERSITY OF HAIFA   (Israel)

^d ARAB AMERICAN UNIVERSITY   (Palestine)

^e Sprunk Jansen A/S   (Denmark)

^f Galilee Society   (Israel)

Author keywords

Arab herbal medicine; CAM; Glucolevel; Hyperglycemia; Medicinal plants

Indexed keywords

ANTIDIABETIC AGENT; ATRIPLEX HALIMUS EXTRACT; GLUCOLEVEL; HEMOGLOBIN A1C; INSULIN; JUGLANS REGIA EXTRACT; LACTATE DEHYDROGENASE; METFORMIN; OLEA EUROPEA EXTRACT; ROSIGLITAZONE; STREPTOZOCIN; UNCLASSIFIED DRUG; URTICA DIOICA EXTRACT;

ABSENCE OF SIDE EFFECTS; ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARAB; ARTICLE; ATRIPLEX HALIMUS; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENTIATION; DRUG SAFETY; DRUG TOLERABILITY; GLUCOSE ABSORPTION; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; GLUCOSE TRANSPORT; HUMAN; INTESTINE ABSORPTION; JUGLANS REGIA; LD 50; MALE; MEDICINAL PLANT; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OLEA EUROPEA; PRIORITY JOURNAL; RAT; TRADITIONAL MEDICINE; TREATMENT DURATION; URTICA DIOICA; YEAST CELL;

EID: 56749179478     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1093/ecam/nem047     Document Type: Article

References (46)

1. Honeycutt AA, Boyle JP, Broglio KR, Thompson TJ, Hoerger TJ, Geiss LS, et al. A dynamic Markov model for forecasting diabetes prevalence in the United States through 2050. Health Care Manag Sci 2003;6:155-64.
2. Zimmet P. The burden of type 2 diabetes: are we doing enough? Diabetes Metab 2003;29:6S9-18.
3. Vuksan V, Sievenpiper JL, Wong J, Xu Z, Beljan-Zdravkovic U, Arnason JT, et al. American ginseng (Panax quinquefolius L.) attenuates postprandial glycemia in a time-dependent but not dose-dependent manner in healthy individuals. Am J Clin Nutr 2001;73:753-8.
4. Nauck MA, Walberg J, Vethacke A, EI-Ouaghlidi A, Senkal M, Holst JJ, et al. Blood glucose control in healthy subject and patients receiving intravenous glucose infusion or total parenteral nutrition using glucagon-like peptide 1. Regul Pept 2004;118:89-97.
5. Berliner JA, Heinecke JW. The role of oxidised lipoproteins in atherogenesis. Free Radic Biol Med 1996;20:707-27.
6. Giugliano D. Dietary antioxidants for cardiovascular prevention. Nutr Metab Cardiovasc Dis 2000;10:38-44.
7. Naito Y, Akagiri S, Uchiyama K, Kokura S, Yoshida N, Hasegawa G, et al. Reduction of diabetes-induced renal oxidative stress by a cantaloupe melon extract/gliadin biopolymers, oxykine, in mice. BioFactors 2005;23:85-95.
8. Said O, Khalil K, Fulder S, Azaizeh H. Ethnopharmacological survey of medical herbs in Israel, the Golan Heights and the West Bank region. J Ethnopharmacology 2002;83:251-65.
9. Azaizeh H, Fulder S, Khalil K, Said O. Ethnobotanical knowledge of local Arab practitioners in the Middle Eastern region: The status of traditional Arabic medicine. Fitoterapia 2003;74:98-108.
10. Bartram T. Encyclopaedia of Herbal Medicine. Dorset, UK: Grace Publishers, 1995.
11. Guarrera PM. Traditional antihelminthic, antiparasitic and repellent uses of plants in central Italy. J Ethnopharmacology 1999;15:183-92.
12. Avicenna (Ibn Sina): The Canon of Medicine. Dar Al-hekma, Beirut.Vol. 2. 526. Arabic.
13. Rhazes (Al Razi): Al Hawi Fi Tib- The comprehensive Book of Medicine. Dar Al-huda, Cairo, Vol. 10, 197. Arabic.
14. Saad B, Azaizeh H, Said O. Tradition and Perspectives of Arab Herbal Medicine: A Review. Evid. Based Complement. Altern. Med 2005;2:475-479.
15. Azaizeh H, Saad B, Khalil KH, Said O. The state of the Art of Traditional Arab Herbal medicine in the Eastern Region of the Mediterranean: A review Evid. Based Complement. Altern. Med 2006;3:229-235.
16. Saad B, Azaizeh H, Abu Hijleh GO. Said. Safety of Traditional Arab Herbal Medicine: A Review. Evidence of Complementary. Alternative Medicine 2006;3:433-39.
17. Anderson KJ, Teuber SS, Gobeille A, Cremin P, Waterhouse AL, Steinberg FM. Walnut polyphenolics inhibit in vitro human plasma and LDL oxidation. J Nutrition 2001;131:2837-42.
18. Fakuda T, Ito H, Yoshida T. Antioxidative polyphenols from walnut (Juglans regia. L.). Phytochemistry 2003;63:795-801.
19. Valderrabano J, Munoz F, Delgado I. Browsing ability and utilization by sheep and goats of Atriplex halimus L. shrubs. Small Ruminant Research 1996;19:131-36.
20. Alicata ML, Amato G, Bonanno V, Giambalvo D, Leto G. In vivo digestibility and nutritive value of Atriplex halimus alone and mixed with wheat straw. J Agricultural Science 2002;139:139-42.
21. Giambalvo D. Characterisation of progeny clones belonging to natural Sicilian Atriplex halimus L. Populations. Tasks for Vegetation Science 1994;32:303-10.
22. Kalderon B, Gutman A, Levy E, Shafrir E, Alder J. Characterization of stages in development of obesity-diabetes syndrome in sand rat (Psammomys obesus). Diabetes 1986;35:717-24.
23. Marles RJ, Farnsworth NR. Antidiabetic plants and their active constituents: An update. Prot J Botanic Medicine 1996;1:85-137.
24. Pinelli P. Quali-quantitative analysis and antioxidant activity of different polyphenolic extracts from Olea Europea L. leaves. J CommodSci (Italy) 2000;39:71-83.
25. Yeilada E, Sezik E, Honda G, Takaishi Y, Takeda Y, Tanaka T. Traditional medicine in Turkey IX: Folk medicine in north-west Anatolia. J Ethnopharmacology 1999;64:195-210.
26. Uncini-Manganelli RE, Tomei PE. Ethnopharmacobotanical studies of Tuscan Archipelago. J Ethnopharmacology 1999;65:181-202.
27. The Complete German Commission E Monographs.. Integrative Medicine 1999.
28. The Martindals. The Extra Pharmacopeia, 27 edn. Pharmaceutical Press, 1978.
29. Friedman J, Yaniv Z, Dafni A, Palewitch D. A preliminary classification of the healing potential of medical plants, based on a rational analysis of an ethnopharmacological field survey among Bedouins in the Negev desert, Israel. J Ethnopharm 1986;16:275-87.
30. Vijayendran Raghevendran, Jens Nielsen, Lisbeth Olsson. Teaching Microbial Physiology Using Glucose Repression Phenomenon in Baker's Yeast as an Example Biochemistry and Molecular Biology Education. 2005; 33: 404-10.
31. Larneer J, Pohl SL, eds. Methods in Diabetes Research, volume 1: Laboratory Methods, part A. New York: Wiley, 1984.
32. Laura DeLong Frost: Glucose Assays Revisited: Experimental determination of the glucose concentration in honey. The Chemical Educator, Vol 9, No. 4, published on Web 7/7/2004.
33. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951;193:265-75.
34. Edelman SV. Type II diabetes mellitus. Adv Intern Med 1998;43:449-500.
35. Guerrero-Romero F, Rodriguez-Moran M. Review Article. Complementary therapies for diabetes: The case for Chromium, Magnesium and antioxidants. Arch Med Res 2005;36:250-7.
36. Shani J, Ahronson Z, Sulman FG, Mertz W, Frenkel G, Kraicer PF. Insulin-potentiating effect of salt bush (Atriplex halimus L.) ashes. Israel J Med Sci 1972;8:757-8.
37. Metzker H, Keiser M, Holscher U. Efficacy of a combined sabalurtica preparation in the treatment of benign prostatic hyperplasia (BPH). Urologie 1996;36B:292-300.
38. Haque R, Bin-Hafeez B, Parvez S, Pandey S, Sayeed I, Ali M, et al. Extract of walnut (Juglans regia. L.) protects mice against cyclophosphamide-Induced biochemical toxicity. Hum Exp Toxicol 2003;22:473-80.
39. El-Gougary OA. Insecticidal and synergistic activity of Atriplex halimus L. extracts. J Egypt Soc Parasitol 1998;28:191-6.
40. Fehri B, Aiache JM, Memmi A, Korbi S, Yacoubi MT, Mrad S, et al. Hypotension, hypoglycaemia and hypouricemia recorded after repeated administration of aqueous leaf extract of Olea europea L. J Pharm Belg 1994;49:101-8.
41. Cherif S, Rahal N, Haouala M, Hizaoui B, Dargouth F, Gueddiche M, et al. A clinical trial of a titrated Olea extract in the treatment of essential arterial hypertension. J Pharm Belg 1996;51:69-71.
42. Gonzalez M, Zarzuelo A, Gamez MJ, Utrilla MP, Jimenez J, Osuna I. Hypoglycemic activity of olive leaf. Planta Medica 1992;58:513-5.
43. Ohsugi M, Fan W, Hase K, Xiong Q, Tezuka Y, Komatsu K, et al. Active oxygen scavenging activity of traditional nourishing-tonic herbal medicines and active constituents of Rhodiola Sacra. J Ethnopharmacology 1999;67:111-19.
44. Oliver-Bever B, Zahnd GR. Plants with oral hypoglycemic activity. Quart J Crude Drug Res 1979;17:139-96.
45. Allen M, Millett P, Dawes E, Rushton N. Lactate dehydrogenase activity as a rapid and sensitive test for the quantification of cell numbers in vitro. Clin Mater 1994;16:189-94.
46. Saudek CD, Derr RL, Kalyani RR. Assessing glycemia in diabetes using self-monitoring blood glucose and hemoglobin A1C. JAMA 2006;295:1688-97.