MUC16 expression during embryogenesis, in adult tissues, and ovarian cancer in the mouse

Differentiation

Volumn 76, Issue 10, 2008, Pages 1081-1092

  Wang, Ying ^a   Cheon, Dong Joo ^a   Lu, Zhen ^a   Cunningham, Sheena L ^b   Chen, Chun Ming ^a,d   Luo, Robert Z ^a   Xing, Deyin ^c   Orsulic, Sandra ^c   Bast Jr , Robert C ^a   Behringer, Richard R ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b Des Moines University College of Osteopathic Medicine   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

CA125; Muc16; Mucin; Ovarian cancer

Indexed keywords

CA 125 ANTIGEN; MUCIN; MUCIN 16; POLYCLONAL ANTIBODY; RECOMBINANT ANTIGEN; RNA; UNCLASSIFIED DRUG;

AMNION; ANIMAL CELL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; COCHLEA DUCT; EMBRYO; EMBRYO DEVELOPMENT; EPITHELIUM; FEMALE; FEMALE GENITAL SYSTEM; GENE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LUNG ALVEOLUS EPITHELIUM; MALE; MALE GENITAL SYSTEM; MESOTHELIUM; MOUSE; MOUTH MUCOSA; MUCIN 16 GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; OLFACTORY EPITHELIUM; OVARY CANCER; PELVIS; PERITONEAL CAVITY; PLEURA CAVITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH CHIEF CELL; TRACHEA MUCOSA; TUMOR DIFFERENTIATION;

MURINAE; ORYCTOLAGUS CUNICULUS;

EID: 56749175360     PISSN: 03014681     EISSN: 14320436     Source Type: Journal    
DOI: 10.1111/j.1432-0436.2008.00295.x     Document Type: Article

References (36)

1. Argüeso, P., Spurr-Michaud, S., Russo, C.L., Tisdale, A. Gipson, I.K. (2003) MUC16 mucin is expressed by the human ocular surface epithelia and carries the H185 carbohydrate epitope. Invest Ophthalmol Vis Sci 44 : 2487 2495.
2. Bast, R.C. Jr., Feeney, M., Lazarus, H., Nadler, L.M., Colvin, R.B. Knapp, R.C. (1981) Reactivity of a monoclonal antibody with human ovarian carcinoma. J Clin Invest 68 : 1331 1337.
3. Bast, R.C. Jr., Klug, T.L., St.John, E., Jenison, E., Niloff, J.M., Lazarus, H., Berkowitz, R.S., Leavitt, T., Griffiths, C.T., Parker, L., Zurawski, V.R. Jr. Knapp, R.C. (1983) A radioimmunoassay using a monoclonal antibody to monitor the course of epithelial ovarian cancer. N Engl J Med 309 : 883 887.
4. Bast, R.C. Jr., Xu, F.J., Yu, Y.H., Barnhill, S., Zhang, Z. Mills, G.B. (1998) CA125: the past and the future. Int J Biol Markers 13 : 179 187.
5. Davies, J.R., Kirkham, S., Svitacheva, N., Thornton, D.J. Carlstedt, I. (2007) MUC16 is produced in tracheal surface epithelium and submucosal glands and is present in secretions from normal human airway and cultured bronchial epithelial cells. Int J Biochem Cell Biol 39 : 1943 1954.
6. Davis, H.M., Zurawski, V.R. Jr., Bast, R.C. Jr. Klug, T.L. (1986) Characterization of the CA125 antigen associated with human epithelial ovarian carcinomas. Cancer Res 46 : 6143 6148.
7. De los Frailes, M.T., Stark, S., Jaeger, W., Hoerauf, A. Wildt, L. (1993) Purification and characterization of the CA125 tumor-associated antigen from human ascites. Tumour Biol 14 : 18 29.
8. Gaetje, R., Winnekendonk, D.W., Ahr, A. Kaufmann, M. (2002) Ovarian cancer antigen CA125 influences adhesion of human and mammalian cell lines in vitro. Clin Exp Obstet Gynecol 29 : 34 36.
9. Gubbels, J.A., Belisle, J., Onda, M., Rancourt, C., Migneault, M., Ho, M., Bera, T.K., Connor, J., Sathyanarayana, B.K., Lee, B., Pastan, I. Patankar, M.S. (2006) Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumors. Mol Cancer 5 : 50 65.
10. Hardardottir, H., Parmley, T.H. II., Quirk, J.G. Jr., Sanders, M.M., Miller, F.C. O'Brien, TJ. (1990) Distribution of CA125 in embryonic tissues and adult derivatives of the fetal periderm. Am J Obstet Gynecol 163 : 1925 1931.
11. Jäger, K., Wu, G., Sel, S., Garreis, F., Bräuer, L. Paulsen, F.P. (2007) MUC16 in the lacrimal apparatus. Histochem Cell Biol 127 : 433 438.
12. Kabawat, S.E., Bast, R.C. Jr., Bhan, A.K., Welch, W.R., Knapp, R.C. Colvin, R.B. (1983) Tissue distribution of a coelomic-epithelium-related antigen recognized by the monoclonal antibody OC125. Int J Gynecol Pathol 2 : 275 285.
13. Kobayashi, H., Ida, W., Terao, T. Kaeashima, Y. (1993) Molecular characteristics of the CA125 antigen produced by human endometrial epithelial cells: comparison between eutopic and heterotopic epithelial cells. Am J Obestet Gynecol 169 : 725 730.
14. Lloyd, K.O., Yin, B.W.T. Kudryashov, V. (1997) Isolation and characterization of ovarian cancer antigen CA125 using a new monoclonal antibody (VK-8): identification as a mucin-type molecule. Int J Cancer 71 : 842 850.
15. Lloyd, K.O. Yin, B.W.T. (2001) Synthesis and secretion of the ovarian cancer antigen CA125 by the human cancer cell line NIH:OVCAR-3. Tumor Biol 22 : 77 82.
16. Maeda, T., Inoue, M., Koshiba, S., Yabuki, T., Aoki, M., Nunokawa, E., Seki, E., Matsuda, T., Motoda, Y., Kobayashi, A., Hiroyasu, F., Shirouzu, M., Terada, T., Hayami, N., Ishizuka, Y., Shinya, N., Tatsuguchi, A., Yoshida, M., Hirota, H., Matsuo, Y., Tani, K., Arakawa, T., Carninci, P., Kawai, J., Hayashizaki, Y., Kigawa, T. Yokoyama, S. (2004) Solution structure of the SEA domain from the murine homologue of ovarian cancer antigen CA125 (MUC16). J Biol Chem 279 : 13174 13182.
17. McDonnel, A.C., Van Kirk, E.A., Austin, K.J., Hansen, T.R., Belden, E.L. Murdoch, W.J. (2003) Expression of CA-125 by progestational bovine endometrium: prospective regulation and function. Reproduction 126 : 615 620.
18. Mutsaers, S.E. (2002) Mesothelial cells: their structure, function and role in serosal repair. Respirology 7 : 171 191.
19. Nagata, A., Hirota, N., Sakai, T., Fujimoto, M. Komoda, T. (1991) Molecular nature and possible presence of a membranous glycan- phosphatidylinositol anchor of CA125 antigen. Tumour Biol 12 : 279 286.
20. Nanbu, Y., Fujii, S., Konishi, I., Nonogaki, H. Mori, T. (1989) CA125 in the epithelium closely related to the embryonic ectoderm: the periderm and the amnion. Am J Obstet Gynecol 161 : 462 467.
21. Nap, M. (1998) Immunohistochemistry of CA125. Unusual expression in normal tissues, distribution in the human fetus and questions around its application in diagnostic pathology. Int J Biol Markers 13 : 210 215.
22. Nouwen, E.J., Pollet, D.E., Eerdekens, M.W., Hendrix, P.G., Briers, T.W. De Broe, M.E. (1986) Immunohistochemical localization of placental alkaline phosphatase, carcinoembryonic antigen, and cancer antigen 125 in normal and neoplastic human lung. Cancer Res 46 : 866 876.
23. Nouwen, E.J., Hendrix, P.G., Dauwe, S., Eerdekens, M.W. De Broe, M.E. (1987) Tumor markers in the human ovary and its neoplasms. A comparative immunohistochemical study. Am J Pathol 126 : 230 242.
24. Nouwen, E.J., Dauwe, S. De Broe, M.E. (1990) Occurrence of the mucinous differentiation antigen CA125 in genital tract and conductive airway epithelia of diverse mammalian species (rabbit, dog, monkey). Differentiation 45 : 192 198.
25. O'Brien, T.J., Beard, J.B., Underwood, L.J., Dennis, R.A., Santin, A.D. York, L. (2001) The CA125 gene: an extracellular superstructure dominated by repeat sequences. Tumour Biol 22 : 348 366.
26. O'Brien, T.J., Beard, J.B., Underwood, L.J. Shigemasa, K. (2002) The CA 125 gene: a newly discovered extension of the glycosylated N-terminal domain doubles the size of this extracellular superstructure. Tumour Biol 23 : 154 169.
27. Orsulic, S., Li, Y., Soslow, R.A., Vitale-Cross, L.A., Gutkind, J.S. Varmus, H. (2002) Induction of ovarian cancer by defined multiple genetic changes in a mouse model system. Cancer Cell 1 : 53 62.
28. Perlmann, H. Perlmann, P. (1994) Cell biology: a laboratory handbook. Academic Press Inc., San Diego.
29. Rump, A., Morikawa, Y., Tanaka, M., Minami, S., Umesaki, N., Takeuchi, M. Miyajima, A. (2004) Binding of ovarian cancer antigen CA125/MUC16 to mesothelin mediates cell adhesion. J Biol Chem 279 : 9190 9198.
30. Scholler, N., Garvik, B., Hayden-Ledbetter, M., Kline, T. Urban N. 2007) Development of a CA125-mesothelin cell adhesion assay as a screening tool for biologics discovery. Cancer Lett 247 : 130 136.
31. Simmons, D.M., Arriza, J.L. Swanson, L.W. (1989) A complete protocol for in situ hybridization of messenger RNAs in brain and other tissues with radio-labeled single-stranded RNA probes. J Histotechnol 12 : 169 181.
32. Xing, D. Orsulic, S. (2006) A mouse model for the molecular characterization of brca1-associated ovarian carcinoma. Cancer Res 66 : 8949 8953.
33. Yin, B.W.T. Lloyd, K.O. (2001) Molecular cloning of the CA125 ovarian cancer antigen: identification as a new mucin, MUC16. J Biol Chem 276 : 27371 27375.
34. Yin, B.W.T., Dnistrian, A. Lloyd, K.O. (2002) Ovarian cancer antigen CA125 is encoded by the MUC16 mucin gene. Int J Cancer 98 : 737 740.
35. Yu, Y.H., Schlossman, D.M., Harrison, C.L., Rhinehardt-Clark, A., Soper, J.T., Klug, T.L., Zurawski, V.R. Jr. Bast, R.C. Jr. (1991) Coexpression of different antigenic markers on moieties that bear CA125 determinants. Cancer Res 51 : 468 475.
36. Zeimet, A.G., Offner, F.A., Muller-Holzner, E., Widschwendter, M., Abendstein, B., Fuith, L.C., Daxenbichler, G. Marth, C. (1998) Peritoneum and tissues of the female reproductive tract as physiological sources of CA-125. Tumour Biol 19 : 275 282.