Severe acute renal failure following high-dose methotrexate therapy in adults with haematological malignancies: A significant number result from unrecognized co-administration of several drugs

Nephrology Dialysis Transplantation

Volumn 23, Issue 12, 2008, Pages 3762-3766

  De Miguel, Dunia ^a   García Suárez, Julio ^a   Martín, Yolanda ^a   Gil Fernández, Juan José ^a   Burgaleta, Carmen ^a  

^a HOSPITAL UNIVERSITARIO PRÍNCIPE DE ASTURIAS   (Spain)

Author keywords

Gemfibrozil; High dose methotrexate; Piperacillin tazobactam; Risk factors; Severe renal failure

Indexed keywords

CARBOXYPEPTIDASE G2; FUROSEMIDE; GEMFIBROZIL; METHOTREXATE; PIPERACILLIN PLUS TAZOBACTAM;

ACUTE KIDNEY FAILURE; ACUTE LYMPHOBLASTIC LEUKEMIA; ADULT; AMINOTRANSFERASE BLOOD LEVEL; BONE MARROW SUPPRESSION; BRAIN LYMPHOMA; CANCER COMBINATION CHEMOTHERAPY; CASE REPORT; CREATININE BLOOD LEVEL; FEVER; HUMAN; MALE; MUCOSA INFLAMMATION; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; RISK FACTOR; SIDE EFFECT;

ADULT; ANTIMETABOLITES, ANTINEOPLASTIC; BRAIN NEOPLASMS; DRUG INTERACTIONS; GEMFIBROZIL; HEMATOLOGIC NEOPLASMS; HUMANS; KIDNEY FAILURE, ACUTE; LYMPHOMA; MALE; METHOTREXATE; MIDDLE AGED; PRECURSOR B-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; RETROSPECTIVE STUDIES; RISK FACTORS;

EID: 56749175314     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfn503     Document Type: Review

References (17)

1. Widemann BC, Balis FM, Kempf-Bielack B et al. High-dose methotrexate-induced nephrotoxicity in patients with osteosarcoma. Cancer 2004; 100: 2222-2232
2. Widemann BC, Adamson PC. Understanding and managing methotrexate nephrotoxicity. The Oncologist 2006; 11: 694-703
3. Buchen S, Ngampolo D, Melton RG et al. Carboxypeptidase G2 rescue in patients with methotrexate intoxication and renal failure. Br J Cancer 2005; 92: 480-487
4. Naranjo CA, Busto U, Sellers EM et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981; 30: 239-245
5. Van Den Bongard HJ, Mathjt RA, Boogerd W et al. Successful rescue with leucovorin and thymidine in a patient with high-dose methotrexate induced acute renal failure. Cancer Chemother Pharmacol 2001; 47: 537-540
6. Ribera J, Oriol A, Morgades M et al. Treatment of high-risk (HR) Philadelphia chromosome-negative (Ph-) adult acute lymphoblastic leukemia (ALL) according to classical risk factors and minimal residual disease (MRD). Interim results of the PETHEMA ALL-AR-03 trial. ASH Meeting, Orlando, 2006; Abstract no. 1872
7. Widemann BC, Hetherington ML, Murphy RF et al. Carboxypeptidase-G2 rescue in a patient with high dose methotrexate-induced nephrotoxicity. Cancer 1995; 76: 521-526
8. Kawabata K, Makino H, Nagake Y et al. A case of methotrexate-induced acute renal failure successfully treated with plasma perfusion and sequential hemodialysis. Nephron 1995; 71: 233-234
9. Yamamoto K, Sawada Y, Matsushita Y et al. Delayed elimination of methotrexate associated with piperacillin administration. Ann Pharmacother 1997; 31: 1261-1262
10. DeAngelis LM, Seiferheld W, Schold SC et al. (Therapy Oncology Group Study 93-10). Combination chemotherapy and radiotherapy for primary central nervous system lymphoma: Radiation Therapy Oncology Group Study 93-10. J Clin Oncol 2002; 20: 4643-4648
11. Dalle JH, Auvrignon A, Vassal G et al. Methotrexate-ciprofloxacin interaction: report of two cases of severe intoxication. Arch Pediatr 2001; 8: 1078-1081
12. Dalle JH, Auvrignon A, Vassal G et al. Interaction between methotrexate and ciprofloxacin. J Pediatr Hematol Oncol 2002; 24: 321-322
13. Titier K, Lagrange F, Phourcq F et al. Pharmacokinetic interaction between high-dose methotrexate and oxacillin. Ther Drug Monit 2002; 24: 570-572
14. Cecyn KZ, Lee J, Oguro T et al. Use of plasma exchange in methotrexate removal in a patient with osteosarcoma and acute renal insufficiency. Am J Hematol 2003; 72: 209-211
15. Fong CM, Lee AC. High-dose methotrexate-associated acute renal failure may be an avoidable complication. Pediatr Hematol Oncol 2006; 23: 51-57
16. Zarychanski R, Wlodarczyk K, Ariano R et al. Pharmacokinetic interaction between methotrexate and piperacillin/tazobactam resulting in prolonged toxic concentrations of methotrexate. J Antimicrob Chemother 2006; 58: 228-230
17. Green MR, Chamberlain MC. Renal dysfunction during and after high-dose methotretate. Cancer Chemother Pharmacol 2008; 27