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Volumn 6, Issue 12, 2008, Pages 2048-2054

Risk stratification for inhibitor development at first treatment for severe hemophilia A: A tool for clinical practice

Author keywords

Antibody; Hemophilia A; Intensive treatment; Risk score

Indexed keywords

BLOOD CLOTTING FACTOR 8 ANTIBODY; KOGENATE BAYER; RECOMBINANT BLOOD CLOTTING FACTOR 8; UNCLASSIFIED DRUG;

EID: 56749175272     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2008.03187.x     Document Type: Article
Times cited : (78)

References (41)
  • 2
    • 34249690732 scopus 로고    scopus 로고
    • Treatment-related risk factors of inhibitor development in previously untreated patients with hemophilia A: The CANAL cohort study
    • Gouw SC, van der Bom JG, van den Berg HM. Treatment-related risk factors of inhibitor development in previously untreated patients with hemophilia A: The CANAL cohort study. Blood 2007; 109: 4648-54.
    • (2007) Blood , vol.109 , pp. 4648-4654
    • Gouw, S.C.1    van der Bom, J.G.2    van den Berg, H.M.3
  • 3
    • 0038383605 scopus 로고    scopus 로고
    • The epidemiology of inhibitors in haemophilia A: A systematic review
    • Wight J, Paisley S. The epidemiology of inhibitors in haemophilia A: A systematic review. Haemophilia 2003; 9: 418-35.
    • (2003) Haemophilia , vol.9 , pp. 418-435
    • Wight, J.1    Paisley, S.2
  • 4
    • 22544473061 scopus 로고    scopus 로고
    • The Malmo International Brother Study (MIBS). Genetic defects and inhibitor development in siblings with severe hemophilia A
    • Astermark J, Oldenburg J, Escobar M, White GC, Berntorp E. The Malmo International Brother Study (MIBS). Genetic defects and inhibitor development in siblings with severe hemophilia A. Haematologica 2005; 90: 924-31.
    • (2005) Haematologica , vol.90 , pp. 924-931
    • Astermark, J.1    Oldenburg, J.2    Escobar, M.3    White, G.C.4    Berntorp, E.5
  • 6
    • 6644227418 scopus 로고    scopus 로고
    • The Malmo International Brother Study (MIBS): Further support for genetic predisposition to inhibitor development in hemophilia patients
    • Astermark J, Berntorp E, White GC, Kroner BL. The Malmo International Brother Study (MIBS): Further support for genetic predisposition to inhibitor development in hemophilia patients. Haemophilia 2001; 7: 267-72.
    • (2001) Haemophilia , vol.7 , pp. 267-272
    • Astermark, J.1    Berntorp, E.2    White, G.C.3    Kroner, B.L.4
  • 7
    • 33646140127 scopus 로고    scopus 로고
    • Why do inhibitors develop? Principles of and factors influencing the risk for inhibitor development in haemophilia
    • Astermark J. Why do inhibitors develop? Principles of and factors influencing the risk for inhibitor development in haemophilia. Haemophilia 2006; 12 (Suppl. 3): 52-60.
    • (2006) Haemophilia , vol.12 , Issue.SUPPL. 3 , pp. 52-60
    • Astermark, J.1
  • 10
    • 0031598278 scopus 로고    scopus 로고
    • Inhibitors occur more frequently in African-American and Latino haemophiliacs
    • Aledort LM, Dimichele DM. Inhibitors occur more frequently in African-American and Latino haemophiliacs. Haemophilia 1998; 4: 68.
    • (1998) Haemophilia , vol.4 , pp. 68
    • Aledort, L.M.1    Dimichele, D.M.2
  • 11
    • 0032787813 scopus 로고    scopus 로고
    • Incidence of inhibitors in haemophilia A patients - A review of recent studies of recombinant and plasma-derived factor VIII concentrates
    • Scharrer I, Bray GL, Neutzling O. Incidence of inhibitors in haemophilia A patients - a review of recent studies of recombinant and plasma-derived factor VIII concentrates. Haemophilia 1999; 5: 145-54.
    • (1999) Haemophilia , vol.5 , pp. 145-154
    • Scharrer, I.1    Bray, G.L.2    Neutzling, O.3
  • 12
    • 33845239946 scopus 로고    scopus 로고
    • Polymorphisms in the TNFA gene and the risk of inhibitor development in patients with hemophilia A
    • Astermark J, Oldenburg J, Carlson J, Pavlova A, Kavakli K, Berntorp E, Lefvert AK. Polymorphisms in the TNFA gene and the risk of inhibitor development in patients with hemophilia A. Blood 2006; 108: 3739-45.
    • (2006) Blood , vol.108 , pp. 3739-3745
    • Astermark, J.1    Oldenburg, J.2    Carlson, J.3    Pavlova, A.4    Kavakli, K.5    Berntorp, E.6    Lefvert, A.K.7
  • 13
    • 33645751563 scopus 로고    scopus 로고
    • Polymorphisms in the IL10 but not in the IL1beta and IL4 genes are associated with inhibitor development in patients with hemophilia A
    • Astermark J, Oldenburg J, Pavlova A, Berntorp E, Lefvert AK. Polymorphisms in the IL10 but not in the IL1beta and IL4 genes are associated with inhibitor development in patients with hemophilia A. Blood 2006; 107: 3167-72.
    • (2006) Blood , vol.107 , pp. 3167-3172
    • Astermark, J.1    Oldenburg, J.2    Pavlova, A.3    Berntorp, E.4    Lefvert, A.K.5
  • 14
    • 33846420672 scopus 로고    scopus 로고
    • Polymorphisms in the CTLA-4 gene and inhibitor development in patients with severe hemophilia A
    • Astermark J, Wang X, Oldenburg J, Berntorp E, Lefvert AK. Polymorphisms in the CTLA-4 gene and inhibitor development in patients with severe hemophilia A. J Thromb Haemost 2007; 5: 263-5.
    • (2007) J Thromb Haemost , vol.5 , pp. 263-265
    • Astermark, J.1    Wang, X.2    Oldenburg, J.3    Berntorp, E.4    Lefvert, A.K.5
  • 17
    • 0034994489 scopus 로고    scopus 로고
    • Incidence of factor VIII inhibitors in severe haemophilia: The importance of patient age
    • Lorenzo JI, Lopez A, Altisent C, Aznar JA. Incidence of factor VIII inhibitors in severe haemophilia: The importance of patient age. Br J Haematol 2001; 113: 600-3.
    • (2001) Br J Haematol , vol.113 , pp. 600-603
    • Lorenzo, J.I.1    Lopez, A.2    Altisent, C.3    Aznar, J.A.4
  • 18
    • 34250708408 scopus 로고    scopus 로고
    • Treatment characteristics and the risk of inhibitor development: A multi-center cohort study among previously untreated patients with severe hemophilia A
    • Gouw SC, van den Berg HM, Le CS, van der Bom JG. Treatment characteristics and the risk of inhibitor development: A multi-center cohort study among previously untreated patients with severe hemophilia A. J Thromb Haemost 2007; 5: 1383-90.
    • (2007) J Thromb Haemost , vol.5 , pp. 1383-1390
    • Gouw, S.C.1    van den Berg, H.M.2    Le, C.S.3    van der Bom, J.G.4
  • 20
  • 22
    • 0033574245 scopus 로고    scopus 로고
    • Assessing the generalizability of prognostic information
    • Justice AC, Covinsky KE, Berlin JA. Assessing the generalizability of prognostic information. Ann Intern Med 1999; 130: 515-24.
    • (1999) Ann Intern Med , vol.130 , pp. 515-524
    • Justice, A.C.1    Covinsky, K.E.2    Berlin, J.A.3
  • 23
    • 33644855006 scopus 로고    scopus 로고
    • Translating clinical research into clinical practice: Impact of using prediction rules to make decisions
    • Reilly BM, Evans AT. Translating clinical research into clinical practice: Impact of using prediction rules to make decisions. Ann Intern Med 2006; 144: 201-9.
    • (2006) Ann Intern Med , vol.144 , pp. 201-209
    • Reilly, B.M.1    Evans, A.T.2
  • 24
    • 0028266130 scopus 로고
    • A multicenter study of recombinant factor VIII (Recombinate): Safety, efficacy, and inhibitor risk in previously untreated patients with hemophilia A. The Recombinate Study Group
    • Bray GL, Gomperts ED, Courter S, Gruppo R, Gordon EM, Manco-Johnson M, Shapiro A, Scheibel E, White G III, Lee M. A multicenter study of recombinant factor VIII (Recombinate): Safety, efficacy, and inhibitor risk in previously untreated patients with hemophilia A. The Recombinate Study Group. Blood 1994; 83: 2428-35.
    • (1994) Blood , vol.83 , pp. 2428-2435
    • Bray, G.L.1    Gomperts, E.D.2    Courter, S.3    Gruppo, R.4    Gordon, E.M.5    Manco-Johnson, M.6    Shapiro, A.7    Scheibel, E.8    White, G.9    Lee, M.10
  • 25
    • 0034964673 scopus 로고    scopus 로고
    • Clinical evaluation of B-domain deleted recombinant factor VIII in previously untreated patients
    • Courter SG, Bedrosian CL. Clinical evaluation of B-domain deleted recombinant factor VIII in previously untreated patients. Semin Hematol 2001; 38: 52-9.
    • (2001) Semin Hematol , vol.38 , pp. 52-59
    • Courter, S.G.1    Bedrosian, C.L.2
  • 26
    • 17944404210 scopus 로고    scopus 로고
    • Safety and efficacy of KOGENATE(R) Bayer in previously untreated patients (PUPs) and minimally treated patients (MTPs)
    • Giangrande PL. Safety and efficacy of KOGENATE(R) Bayer in previously untreated patients (PUPs) and minimally treated patients (MTPs). Haemophilia 2002; 8 (Suppl. 2): 19-22.
    • (2002) Haemophilia , vol.8 , Issue.SUPPL. 2 , pp. 19-22
    • Giangrande, P.L.1
  • 27
    • 0001819208 scopus 로고    scopus 로고
    • Safety and immunogenicity of recombinant factor VIII (Recombinate) in previously untreated patients (PUPs): A 6.5 year update. The Recombinate PUP study Group
    • (abstract PD-663)
    • Gruppo R, Bray GL, Schroth P, Perry M, Gomperts ED. Safety and immunogenicity of recombinant factor VIII (Recombinate) in previously untreated patients (PUPs): A 6.5 year update. The Recombinate PUP study Group. Thromb Haemost 1997; 77: 162 (abstract PD-663).
    • (1997) Thromb Haemost , vol.77 , pp. 162
    • Gruppo, R.1    Bray, G.L.2    Schroth, P.3    Perry, M.4    Gomperts, E.D.5
  • 28
    • 15344351616 scopus 로고    scopus 로고
    • Full-length sucrose-formulated recombinant factor VIII for treatment of previously untreated or minimally treated young children with severe haemophilia A: Results of an international clinical investigation
    • Kreuz W, Gill JC, Rothschild C, Manco-Johnson MJ, Lusher JM, Kellermann E, Gorina E, Larson PJ. Full-length sucrose-formulated recombinant factor VIII for treatment of previously untreated or minimally treated young children with severe haemophilia A: Results of an international clinical investigation. Thromb Haemost 2005; 93: 457-67.
    • (2005) Thromb Haemost , vol.93 , pp. 457-467
    • Kreuz, W.1    Gill, J.C.2    Rothschild, C.3    Manco-Johnson, M.J.4    Lusher, J.M.5    Kellermann, E.6    Gorina, E.7    Larson, P.J.8
  • 29
    • 0027473752 scopus 로고
    • Recombinant factor VIII for the treatment of previously untreated patients with hemophilia A. Safety, efficacy, and development of inhibitors. Kogenate Previously Untreated Patient Study Group
    • Lusher JM, Arkin S, Abildgaard CF, Schwartz RS. Recombinant factor VIII for the treatment of previously untreated patients with hemophilia A. Safety, efficacy, and development of inhibitors. Kogenate Previously Untreated Patient Study Group. N Engl J Med 1993; 328: 453-9.
    • (1993) N Engl J Med , vol.328 , pp. 453-459
    • Lusher, J.M.1    Arkin, S.2    Abildgaard, C.F.3    Schwartz, R.S.4
  • 30
    • 0037276262 scopus 로고    scopus 로고
    • The safety and efficacy of B-domain deleted recombinant factor VIII concentrate in patients with severe haemophilia A
    • Lusher JM, Lee CA, Kessler CM, Bedrosian CL. The safety and efficacy of B-domain deleted recombinant factor VIII concentrate in patients with severe haemophilia A. Haemophilia 2003; 9: 38-49.
    • (2003) Haemophilia , vol.9 , pp. 38-49
    • Lusher, J.M.1    Lee, C.A.2    Kessler, C.M.3    Bedrosian, C.L.4
  • 31
    • 19444363534 scopus 로고    scopus 로고
    • The safety and efficacy of B-domain deleted recombinant factor VIII concentrates in patients with severe haemophilia A: An update
    • Lusher JM, Roth DA. The safety and efficacy of B-domain deleted recombinant factor VIII concentrates in patients with severe haemophilia A: An update. Haemophilia 2005; 11: 292-3.
    • (2005) Haemophilia , vol.11 , pp. 292-293
    • Lusher, J.M.1    Roth, D.A.2
  • 33
    • 33748530614 scopus 로고    scopus 로고
    • Imputation of missing values is superior to complete case analysis and the missing-indicator method in multivariable diagnostic research: A clinical example
    • van der Heijden GJ, Donders AR, Stijnen T, Moons KG. Imputation of missing values is superior to complete case analysis and the missing-indicator method in multivariable diagnostic research: A clinical example. J Clin Epidemiol 2006; 59: 1102-9.
    • (2006) J Clin Epidemiol , vol.59 , pp. 1102-1109
    • van der Heijden, G.J.1    Donders, A.R.2    Stijnen, T.3    Moons, K.G.4
  • 35
    • 0025151933 scopus 로고
    • Predictive value of statistical models
    • van Houwelingen JC, Le Cessie S. Predictive value of statistical models. Stat Med 1990; 9: 1303-25.
    • (1990) Stat Med , vol.9 , pp. 1303-1325
    • van Houwelingen, J.C.1    Le Cessie, S.2
  • 36
    • 0037066427 scopus 로고    scopus 로고
    • The danger model: A renewed sense of self
    • Matzinger P. The danger model: A renewed sense of self. Science 2002; 296: 301-5.
    • (2002) Science , vol.296 , pp. 301-305
    • Matzinger, P.1
  • 37
    • 33845485057 scopus 로고    scopus 로고
    • Mechanisms of action of immune tolerance induction against factor VIII in patients with congenital haemophilia A and factor VIII inhibitors
    • Reipert BM, van Helden PM, Schwarz HP, Hausl C. Mechanisms of action of immune tolerance induction against factor VIII in patients with congenital haemophilia A and factor VIII inhibitors. Br J Haematol 2007; 136: 12-25.
    • (2007) Br J Haematol , vol.136 , pp. 12-25
    • Reipert, B.M.1    van Helden, P.M.2    Schwarz, H.P.3    Hausl, C.4
  • 39
    • 0026635406 scopus 로고
    • Twenty-five years' experience of prophylactic treatment in severe haemophilia A and B
    • Nilsson IM, Berntorp E, Lofqvist T, Pettersson H. Twenty-five years' experience of prophylactic treatment in severe haemophilia A and B. J Intern Med 1992; 232: 25-32.
    • (1992) J Intern Med , vol.232 , pp. 25-32
    • Nilsson, I.M.1    Berntorp, E.2    Lofqvist, T.3    Pettersson, H.4
  • 41
    • 33750796998 scopus 로고    scopus 로고
    • Epidemiology of inhibitor formation with recombinant factor VIII replacement therapy
    • Peerlinck K, Hermans C. Epidemiology of inhibitor formation with recombinant factor VIII replacement therapy. Haemophilia 2006; 12: 579-90.
    • (2006) Haemophilia , vol.12 , pp. 579-590
    • Peerlinck, K.1    Hermans, C.2


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