Ligand specificity of constitutive androstane receptor as probed by induced-fit docking and mutagenesis

Journal of Medicinal Chemistry

Volumn 51, Issue 22, 2008, Pages 7119-7131

  Repo, Susanna ^a   Jyrkkärinne, Johanna ^b   Pulkkinen, Juha T ^b   Laatikainen, Reino ^b   Honkakoski, Paavo ^b   Johnson, Mark S ^a  

^a ÅBO AKADEMI UNIVERSITY   (Finland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

CONSTITUTIVE ANDROSTANE RECEPTOR; LIGAND;

ANIMAL EXPERIMENT; ARTICLE; CHEMICAL STRUCTURE; EXPERIMENTAL MOUSE; LIGAND BINDING; MUTAGENESIS; MUTATION; NONHUMAN;

ANIMALS; CLOTRIMAZOLE; CRYSTALLOGRAPHY, X-RAY; ETHINYL ESTRADIOL; HUMANS; LIGANDS; METHOXYCHLOR; MICE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MUTAGENESIS; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SENSITIVITY AND SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION FACTORS;

EID: 56749173772     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm800337r     Document Type: Article

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