Successful treatment with bosentan of non-digital skin ulcers in severe scleroderma

Annals of the Rheumatic Diseases

Volumn 67, Issue 12, 2008, Pages 1784-1785

  Ferreira, M E G ^a   Scheinberg, Morton A ^a  

^a HOSPITAL ISRAELITA ALBERT EINSTEIN   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

BOSENTAN;

ADULT; ANAMNESIS; CASE REPORT; CLINICAL FEATURE; DISEASE COURSE; DISEASE SEVERITY; DRUG DOSE INCREASE; FEMALE; HUMAN; LABORATORY TEST; LETTER; PRIORITY JOURNAL; SCLERODERMA; SKIN ULCER; SYSTEMIC SCLEROSIS; TREATMENT OUTCOME;

FEMALE; HUMANS; LEG ULCER; MIDDLE AGED; RECEPTORS, ENDOTHELIN; SCLERODERMA, SYSTEMIC; SULFONAMIDES;

EID: 56749159745     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/ard.2007.087189     Document Type: Letter

References (7)

1. Korn JH, Mayes M, Matucci Cerinic M, Rainisio M, Pope J, Hachulla E, et al. Digital ulcers in systemic sclerosis: prevention by treatment with bosentan, an oral endothelin receptor antagonist. Arthritis Rheum 2004;50:3985-93.
2. Launay D, Diot E, Pasquier E, Mouthon L, Boullanger N, Fain O, et al. [Bosentan for treatment of active digital ulcers in patients with systemic sclerosis]. Presse Med 2006;35:587-92. (In French.)
3. Yu EP, Ostor AJ, Hall FC. Successful treatment with bosentan for severe digital ischaemia in limited cutaneous systemic sclerosis. Ann Rheum Dis 2007;66:1122-3.
4. Hettema ME, Zhang D, Bootsma H, Kallenberg CG. Bosentan therapy for patients with severe Raynaud's phenomenon in systemic sclerosis. Ann Rheum Dis 2007;66:1398-19.
5. García de la Peña-Lefebvre P, Rodríguez Rubio S, Valero Expósito M, Carmona L, Gámir Gámir ML, Beltrán Gutiérrez J, et al. Long-term experience of bosentan for treating ulcers and healed ulcers in systemic sclerosis patients. Rheumatology (Oxford) 2008 Feb 7; [Epub ahead of print]
6. Rösener I, Rübben A. [Treatment of a leg ulcer with bosentan in a female patient with progressive systemic scleroderma]. Hautarzt 2007;58:392-3. (In German.)
7. Snyder MJ, Jacobs MR, Grau RG, Wilkes DS, Knox KS. Resolution of severe digital ulceration during a course of Bosentan therapy. Ann Intern Med 2005;142:802-3.