Experimental infection of dogs with a Brazilian strain of Rickettsia rickettsii: Clinical and laboratory findings

Memorias do Instituto Oswaldo Cruz

Volumn 103, Issue 7, 2008, Pages 696-701

  Piranda, Eliane M ^a   Faccini, João Luis H ^a   Pinter, Adriano ^b   Saito, Tais B ^c   Pacheco, Richard C ^c   Hagiwara, Mitika K ^c   Labruna, Marcelo B ^c  

^a FEDERAL RURAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b SUPERINTENDÊNCIA DE CONTROLE DE ENDEMIAS   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Brazil; Dog; Rickettsia rickettsii; Spotted fever; Tick

Indexed keywords

BACTERIA (MICROORGANISMS); CANIS FAMILIARIS; IXODIDA; RICKETTSIA; RICKETTSIA RICKETTSII;

BACTERIAL DNA;

ANIMAL; ANIMAL DISEASE; ARTICLE; BLOOD; DISEASE MODEL; DISEASE TRANSMISSION; DOG; DOG DISEASE; FEMALE; MICROBIOLOGY; PATHOGENICITY; RICKETTSIA RICKETTSII; ROCKY MOUNTAIN SPOTTED FEVER; TICK;

ANIMALS; DISEASE MODELS, ANIMAL; DNA, BACTERIAL; DOG DISEASES; DOGS; FEMALE; RICKETTSIA RICKETTSII; ROCKY MOUNTAIN SPOTTED FEVER; TICKS;

EID: 56749156081     PISSN: 00740276     EISSN: 16788060     Source Type: Journal    
DOI: 10.1590/S0074-02762008000700012     Document Type: Article

References (30)

1. Aguiar DM, Cavalcante GT, Pinter A, Gennari SM, Camargo LMA, Labruna MB 2007. Prevalence of Ehrlichia canis (Rickettsiales: Anaplasmataceae) in dogs and Rhipicephalus sanguineus (Acari: Ixodidae) ticks from Brazil. J Med Entomol 44: 126-132.
2. Angerami RN, Resende MR, Feltrin AF, Katz G, Nascimento EM, Stucchi RS, Silva LJ 2006. Brazilian spotted fever: a case series from an endemic area in Southeastern Brazil: clinical aspects. Ann N Y Acad Sci 1078: 252-254.
3. Breitschwerdt EB, Walker DH, Levy MG, Burgdofer W, Cobertt WT, Hurlbert SA, Stebbins ME, Curtins BC, Allen DA 1988. Clinical, hematologic and humoral immune response in female dogs inoculated with Rickettsia rickettsii and Rickettsia montana. Am J Vet Res 49: 70-76.
4. Chapman AS, Murphy SM, Demma LJ, Holman RC, Curns AT, McQuiston JH, Krebs JW, Swerdlow DL 2006. Rocky Mountain spotted fever in the United States, 1997-2002. Ann N Y Acad Sci 1078: 154-155.
5. Comer KM 1991. Rocky Mountain spotted fever. Vet Clin North Am Small Anim Pract 21: 27-48.
6. Elchos BN, Goddard J 2003. Implications of presumptive fatal Rocky Mountain spotted fever in two dogs and their owner. J Am Vet Med Assoc 223: 1450-1452.
7. Eremeeva ME, Klemt RM, Santucci-Domotor LA, Silverman DJ, Dasch GA 2003. Genetic analysis of isolates of Rickettsia rickettsii that differ in virulence. Ann NY Acad Sci 990: 717-722.
8. Galvão MA, Silva LJ, Nascimento EM, Calic SB, Sousa R, Bacellar F 2005. Rickettsial diseases in Brazil and Portugal: occurrence, distribution and diagnosis. Rev Saude Publica 39: 850-856.
9. Gasser AM, Birkenheuer AJ, Breitschwerdt EB 2001. Canine Rocky Mountain spotted fever: a retrospective study of 30 cases. J Am Anim Hosp Assoc 37: 41-48.
10. Greene CE 1987. Rocky Mountain spotted fever. J Am Vet Med Assoc 191: 666-671.
11. Greene CE, Burgdorfer W, Cavagnolo R, Philip RN, Peacock MG 1985. Rocky Mountain spotted fever in dogs and its differentiation from canine ehrlichiosis. J Am Vet Med Assoc 186: 465-472.
12. Grindem CB, Breitschwerdt EB, Perkins PC, Cullins LD, Thomas TJ, Hegarty BC 1999. Platelet-associated immunoglobulin (antiplatelet antibody) in canine Rocky Mountain spotted fever and Ehrlichiosis. J Am Anim Hosp Assoc 35: 56-61.
13. Horta MC, Labruna MB, Pinter A, Linardi PM, Schumaker TTS 2007. Rickettsia infection in five areas of the state of São Paulo. Mem Inst Oswaldo Cruz 102: 793-801.
14. Horta MC, Labruna MB, Sangioni LA, Vianna MCB, Gennari SM, Galvão MA, Mafra CL, Vidotto O, Schumaker TT, Walker DH 2004. Prevalence of antibodies to spotted fever group rickettsiae in humans and domestic animals in a Brazilian spotted fever endemic area in the state of São Paulo, Brazil: serological evidence for infection by Rickettsia rickettsii and another spotted fever group Rickettsia. Am J Trop Med Hyg 71: 93-97.
15. Karpathy SE, Dasch GA, Eremeeva ME 2007. Molecular typing of isolates of Rickettsia rickettsii by use of DNA sequencing of variable intergenic regions. J Clin Microbiol 45: 2545-2553.
16. Keenan KP, Buhles WC, Huxsoll Jr DL, Williams RG, Hildebrandt PK 1977a. Studies on the pathogenesis of Rickettsia rickettsii in the dog: clinical and clinicopathologic changes of experimental infection. Am J Vet Res 38: 851-856.
17. Keenan KP, Buhles WC, Huxsoll Jr DL, Williams RG, Hildebrandt PK, Campbell JM, Stephenson EH 1977b. Pathogenesis of infection with Rickettsia rickettsii in the dog: a disease model for Rocky Mountain spotted fever. J Infect Dis 135: 911-917.
18. Labruna MB, Horta MC, Aguiar DM, Cavalcante GT, Pinter A, Gennari SM, Camargo LMA 2007. Prevalence of Rickettsia infection in dogs from the urban and rural areas of Monte Negro municipality, Western Amazon, Brazil. Vector Borne Zoonotic Dis 7: 249-255.
19. Labruna MB, Whitworth T, Horta MC, Bouyer DH, McBride JW, Pinter A, Popov V, Gennari SM, Walker DH 2004. Rickettsia species infecting Amblyomma cooperi ticks from an area in the state of São Paulo, Brazil, where Brazilian spotted fever is endemic. J Clin Microbiol 42: 90-98.
20. Lemos ERS, Machado RD, Coura JR, Guimarães MAA, Chagas N 1996. Epidemiological aspects of the Brazilian spotted fever: serological survey of dogs and horses in an endemic area in the state of São Paulo, Brazil. Rev Inst Med Trop Sao Paulo 38: 427-430.
21. Magnarelli LA, Anderson JF, Philip RN 1982. Antibodies to spotted fever group rickettsiae in dogs and prevalence of infected ticks of Southern Connecticut. Am J Vet Res 43: 656-659.
22. Norment BR, Burgdorfer W 1984. Susceptibility and reservoir potential of the dog to spotted fever-group rickettsiae. Am J Vet Res 45: 1706-1710.
23. Paddock CD, Brenner O, Vaid C, Boyd DB, Berg JM, Joseph RJ, Zaki SR, Childs JE 2002. Short report: concurrent Rocky Mountain spotted fever in a dog and its owner. Am J Trop Med Hyg 66: 197-199.
24. Paddock CD, Fernandez S, Echenique GA, Sumner JW, Reeves WK, Zaki SR, Remondegui CE 2008. Rocky Mountain spotted fever in Argentina. Am J Trop Med Hyg 78: 687-692.
25. Pinter A, Dias RA, Gennari SM, Labruna MB 2004. Study of the seasonal dynamics, life cycle and host specificity of Amblyomma aureolatum (Acari: Ixodidae). J Med Entomol 41: 324-332.
26. Pinter A, Horta MC, Pacheco RC, Moraes-Filho J, Labruna MB 2008. Serosurvey for Rickettsia spp in dogs and humans from a Brazilian spotted fever endemic area in the state of São Paulo. Cad Saude Publ 24: 247-252.
27. Pinter A, Labruna MB 2006a. Isolation of Rickettsia rickettsii and Rickettsia bellii in cell culture from the tick Amblyomma aureolatum in Brazil. Ann NY Acad Sci 1078: 523-529.
28. Pinter A, Labruna MB 2006b. Competência vetorial de Amblyomma aureolatum na transmissão da bacteria Rickettsia rickettsii. In Proceedings of the 2nd Simpósio Latino-Americano de Rickettsioses, Ribeirão Preto, Brazil, p. 368.
29. Sangioni LA, Horta MC, Vianna MCB, Gennari SM, Soares RS, Galvão MAM, Schumaker TTS, Ferreira F, Vidotto O, Labruna MB 2005. Rickettsial infection in animals and Brazilian spotted fever endemicity. Emerg Infect Dis 11: 265-270.
30. Sexton DJ, Burgdorfer W, Thomas L, Norment BR 1976. Rocky Mountain spotted fever in Mississippi: survey for spotted fever antibodies in dogs and for spotted fever group rickettsiae in dog ticks. Am J Epidemiol 103: 192-197.