Higher folate intake is related to lower risk of alzheimer's disease in the elderly

Journal of Nutrition, Health and Aging

Volumn 12, Issue 9, 2008, Pages 648-650

  Luchsinger, José A ^a,b,f   Tang, M X ^a,c   Miller, J ^d   Green, R ^d   Mayeux, R ^a,b,c,e  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b Columbia University College of Physicians and Surgeons ^*  (United States)

^c University of California ^*  (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e Taub Institute for Research on Alzheimer's Disease and the Aging Brain and the Gertrude H Sergievsky Center   (United States)

^f NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E4; CYANOCOBALAMIN; FOLIC ACID; PYRIDOXINE;

AFRICAN AMERICAN; AGED; ALZHEIMER DISEASE; CAUCASIAN; CONTROLLED STUDY; DIABETES MELLITUS; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; EDUCATIONAL STATUS; ELDERLY CARE; FEEDING BEHAVIOR; FEMALE; FOOD COMPOSITION; FOOD INTAKE; HEART DISEASE; HISPANIC; HUMAN; HYPERTENSION; LETTER; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; QUESTIONNAIRE; RISK REDUCTION; STROKE; TREATMENT OUTCOME; UNITED STATES; VITAMIN SUPPLEMENTATION;

EID: 56749149902     PISSN: 12797707     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Letter

References (5)

1. Seshadri S, BeiseT A, Selhub J, et al. Plasma homocysteme as a risk factor for dementia and Alzheimer's disease. N Engl J Med 2002;346:476-483.
2. Luchsinger JA, Tang MX, Miller J, Green R, Mayeux R. Relation of higher folate intake to lower risk of Alzheimer disease in the elderly. Arch Neurol 2007;64:86-92.
3. Morris MC, Evans DA, Bienias JL, et al. Dietary folate and vitarnin B12 intake and cognitive decline among comm u nity-d welling older persons. Arch Neurol 2005;62:641-645.
4. Morris MS, Jacques PF, Rosenberg IH, Selhub J. Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification. Am J Clin Nutr 2007;85:193-200.
5. McMahon JA, Green TJ, Skeaff CM, Knight RG, Mann JI, Williams SM. A controlled trial of homocysteine lowering and cognitive performance. N Engl J Med 2006;354:2764-2772.