One- and two-metal ion catalysis: Global single-turnover kinetic analysis of the PvuII endonuclease mechanism

Biochemistry

Volumn 47, Issue 47, 2008, Pages 12540-12550

  Xie, Fuqian ^a   Qureshi, Shabir H ^a   Papadakos, Grigorios A ^a   Dupureur, Cynthia M ^a  

^a UNIVERSITY OF MISSOURI ST LOUIS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CALCIUM; CATALYSIS; CONCENTRATION (PROCESS); CURVE FITTING; DNA; ELECTROLYSIS; ESTERS; GENES; HYDROLYSIS; MAGNESIUM PRINTING PLATES; METAL IONS; METALS; NUCLEIC ACIDS; ORGANIC ACIDS; ORGANIC COMPOUNDS; RATE CONSTANTS; TRACE ANALYSIS;

ACID HYDROLYSES; ACTIVE SITES; ASSOCIATION RATE CONSTANTS; CLEAVAGE RATES; COFACTOR; COMPREHENSIVE STUDIES; DATA FITS; DNA CLEAVAGES; ENDONUCLEASE; ESTER HYDROLYSES; GLOBAL FITTINGS; IN VITRO; KINETIC ANALYSES; REACTION PROGRESSES;

IONS;

CALCIUM ION; DNA; ENDONUCLEASE; ENDONUCLEASE PVU2; MAGNESIUM ION; METAL ION; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; COMPLEX FORMATION; DNA BINDING; DNA CLEAVAGE; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME KINETICS; HYDROLYSIS KINETICS; IN VITRO STUDY; METAL BINDING; MOLECULAR DYNAMICS; MOLECULAR MODEL; PRIORITY JOURNAL; STEADY STATE;

BASE SEQUENCE; BIOCATALYSIS; CATALYTIC DOMAIN; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; DNA; KINETICS; METALS; MODELS, CHEMICAL;

EID: 56749148310     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi801027k     Document Type: Article

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