메뉴 건너뛰기




Volumn 178, Issue 11, 2008, Pages 1115-1122

Goblet cell rebound and airway dysfunction with corticosteroid withdrawal in a mouse model of asthma

Author keywords

Airway resistance; Asthma; Glucocorticoids; Goblet cells; Pathophysiology

Indexed keywords

BUDESONIDE; FLUTICASONE; HOUSE DUST ALLERGEN; INTERLEUKIN 13; MUCIN;

EID: 56749105447     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.200801-084OC     Document Type: Article
Times cited : (23)

References (31)
  • 1
    • 0036181314 scopus 로고    scopus 로고
    • The pathophysiology of asthma
    • Maddox L, Schwartz DA. The pathophysiology of asthma. Annu Rev Med 2002;53:477-498.
    • (2002) Annu Rev Med , vol.53 , pp. 477-498
    • Maddox, L.1    Schwartz, D.A.2
  • 3
    • 0030010572 scopus 로고    scopus 로고
    • Relationship between the inflammatory infiltrate in bronchial biopsy specimens and clinical severity of asthma in patients treated with inhaled steroids
    • Sont JK, Han J, van Krieken JM, Evertse CE, Hooijer R, Willems LN, Sterk PJ. Relationship between the inflammatory infiltrate in bronchial biopsy specimens and clinical severity of asthma in patients treated with inhaled steroids. Thorax 1996;51:496-502.
    • (1996) Thorax , vol.51 , pp. 496-502
    • Sont, J.K.1    Han, J.2    van Krieken, J.M.3    Evertse, C.E.4    Hooijer, R.5    Willems, L.N.6    Sterk, P.J.7
  • 4
    • 1842370350 scopus 로고    scopus 로고
    • Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group
    • Pauwels RA, Löfdahl CG, Postma DS, Tattersfield AE, O'Byrne P, Barnes PJ, Ullman A. Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group. N Engl J Med 1997;337:1405-1411.
    • (1997) N Engl J Med , vol.337 , pp. 1405-1411
    • Pauwels, R.A.1    Löfdahl, C.G.2    Postma, D.S.3    Tattersfield, A.E.4    O'Byrne, P.5    Barnes, P.J.6    Ullman, A.7
  • 5
    • 11144336065 scopus 로고    scopus 로고
    • How do we measure the effectiveness of inhaled corticosteroids in clinical studies?
    • Hansel TT. How do we measure the effectiveness of inhaled corticosteroids in clinical studies? Respir Med 2004;98:S9-S15.
    • (2004) Respir Med , vol.98
    • Hansel, T.T.1
  • 6
    • 0034601431 scopus 로고    scopus 로고
    • Low-dose inhaled corticosteroids and the prevention of death from asthma
    • Suissa S, Ernst P, Benayoun S, Baltzan M, Cai B. Low-dose inhaled corticosteroids and the prevention of death from asthma. N Engl J Med 2000;343:332-336.
    • (2000) N Engl J Med , vol.343 , pp. 332-336
    • Suissa, S.1    Ernst, P.2    Benayoun, S.3    Baltzan, M.4    Cai, B.5
  • 7
    • 0028235803 scopus 로고
    • Effects of long-term treatment with an inhaled corticosteroid on growth and pulmonary function in asthmatic children
    • Agertoft L, Pedersen S. Effects of long-term treatment with an inhaled corticosteroid on growth and pulmonary function in asthmatic children. Respir Med 1994;88:373-381.
    • (1994) Respir Med , vol.88 , pp. 373-381
    • Agertoft, L.1    Pedersen, S.2
  • 8
    • 33747674255 scopus 로고    scopus 로고
    • Characteristics of asthma resistant to moderate dose inhaled corticosteroid treatment on bronchial hyperresponsiveness
    • Fujimoto K, Yamaguchi S, Urushibata K, Hanaoka M, Koizumi T, Honda T, Kubo K. Characteristics of asthma resistant to moderate dose inhaled corticosteroid treatment on bronchial hyperresponsiveness. Intern Med 2006;45:843-849.
    • (2006) Intern Med , vol.45 , pp. 843-849
    • Fujimoto, K.1    Yamaguchi, S.2    Urushibata, K.3    Hanaoka, M.4    Koizumi, T.5    Honda, T.6    Kubo, K.7
  • 9
    • 0028804109 scopus 로고
    • Effect of early vs late intervention with inhaled corticosteroids in asthma
    • Selroos O, Pietinalho A, Lofroos AB, Riska H. Effect of early vs late intervention with inhaled corticosteroids in asthma. Chest 1995;108:1228-1234.
    • (1995) Chest , vol.108 , pp. 1228-1234
    • Selroos, O.1    Pietinalho, A.2    Lofroos, A.B.3    Riska, H.4
  • 10
    • 2342523999 scopus 로고    scopus 로고
    • Airway mucus hypersecretion in asthma: An undervalued pathology?
    • Rogers DF. Airway mucus hypersecretion in asthma: an undervalued pathology? Curr Opin Pharmacol 2004;4:241-250.
    • (2004) Curr Opin Pharmacol , vol.4 , pp. 241-250
    • Rogers, D.F.1
  • 11
    • 0036933504 scopus 로고    scopus 로고
    • Goblet cell and mucin gene abnormalities in asthma
    • Fahy JV. Goblet cell and mucin gene abnormalities in asthma. Chest 2002;122:320S-326S.
    • (2002) Chest , vol.122
    • Fahy, J.V.1
  • 12
    • 0036037291 scopus 로고    scopus 로고
    • Airway goblet cell hyperplasia in asthma: Hypersecretory and anti-inflammatory?
    • Rogers DF. Airway goblet cell hyperplasia in asthma: hypersecretory and anti-inflammatory? Clin Exp Allergy 2002;32:1124-1127.
    • (2002) Clin Exp Allergy , vol.32 , pp. 1124-1127
    • Rogers, D.F.1
  • 13
    • 0036940619 scopus 로고    scopus 로고
    • Corticosteroid-induced apoptosis of airway epithelium: A potential mechanism for chronic airway epithelial damage in asthma
    • White SR, Dorscheid DR. Corticosteroid-induced apoptosis of airway epithelium: a potential mechanism for chronic airway epithelial damage in asthma. Chest 2002;122:278S-284S.
    • (2002) Chest , vol.122
    • White, S.R.1    Dorscheid, D.R.2
  • 15
    • 0033208703 scopus 로고    scopus 로고
    • Allergen-induced increase in airway responsiveness, airway eosinophilia, and bone-marrow eosinophil progenitors in mice
    • Inman MD, Ellis R, Wattie J, Denburg JA, O'Byrne PM. Allergen-induced increase in airway responsiveness, airway eosinophilia, and bone-marrow eosinophil progenitors in mice. Am J Respir Cell Mol Biol 1999;21:473-479.
    • (1999) Am J Respir Cell Mol Biol , vol.21 , pp. 473-479
    • Inman, M.D.1    Ellis, R.2    Wattie, J.3    Denburg, J.A.4    O'Byrne, P.M.5
  • 17
    • 34047161752 scopus 로고    scopus 로고
    • Components of airway hyperresponsiveness and their associations with inflammation and remodeling in mice
    • Southam DS, Ellis R, Wattie J, Inman MD. Components of airway hyperresponsiveness and their associations with inflammation and remodeling in mice. J Allergy Clin Immunol 2007;119:848-854.
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 848-854
    • Southam, D.S.1    Ellis, R.2    Wattie, J.3    Inman, M.D.4
  • 18
    • 9244231169 scopus 로고    scopus 로고
    • T-cell-mediated inflammation does not contribute to the maintenance of airway dysfunction in mice
    • Leigh R, Southam DS, Ellis R, Wattie JN, Sehmi R, Wan Y, Inman MD. T-cell-mediated inflammation does not contribute to the maintenance of airway dysfunction in mice. J Appl Physiol 2004;97:2258-2265.
    • (2004) J Appl Physiol , vol.97 , pp. 2258-2265
    • Leigh, R.1    Southam, D.S.2    Ellis, R.3    Wattie, J.N.4    Sehmi, R.5    Wan, Y.6    Inman, M.D.7
  • 20
    • 0141478647 scopus 로고    scopus 로고
    • Morphometric analysis of mouse airways after chronic allergen challenge
    • Ellis R, Leigh R, Southam D, O'Byrne PM, Inman MD. Morphometric analysis of mouse airways after chronic allergen challenge. Lab Invest 2003;83:1285-1291.
    • (2003) Lab Invest , vol.83 , pp. 1285-1291
    • Ellis, R.1    Leigh, R.2    Southam, D.3    O'Byrne, P.M.4    Inman, M.D.5
  • 23
    • 0035190667 scopus 로고    scopus 로고
    • Airway mucus obstruction: Mucin glycoproteins, MUC gene regulation and goblet cell hyperplasia
    • Rose MC, Nickola TJ, Voynow JA. Airway mucus obstruction: mucin glycoproteins, MUC gene regulation and goblet cell hyperplasia. Am J Respir Cell Mol Biol 2001;25:533-537.
    • (2001) Am J Respir Cell Mol Biol , vol.25 , pp. 533-537
    • Rose, M.C.1    Nickola, T.J.2    Voynow, J.A.3
  • 24
    • 0035891783 scopus 로고    scopus 로고
    • Remodeling of the airway epithelium in asthma
    • Fahy JV. Remodeling of the airway epithelium in asthma. Am J Respir Crit Care Med 2001;164:S46-S51.
    • (2001) Am J Respir Crit Care Med , vol.164
    • Fahy, J.V.1
  • 26
    • 5144224760 scopus 로고    scopus 로고
    • Is interleukin-13 critical in maintaining airway hyperresponsiveness in allergen-challenged mice?
    • Leigh R, Ellis R, Wattie J, Donaldson DD, Inman MD. Is interleukin-13 critical in maintaining airway hyperresponsiveness in allergen-challenged mice? Am J Respir Crit Care Med 2004;170:851-856.
    • (2004) Am J Respir Crit Care Med , vol.170 , pp. 851-856
    • Leigh, R.1    Ellis, R.2    Wattie, J.3    Donaldson, D.D.4    Inman, M.D.5
  • 30
    • 25144451471 scopus 로고    scopus 로고
    • Canadian Network for Asthma Care; Canadian Thoracic Society. Canadian pediatric asthma consensus guidelines, 2003 (updated to December 2004): Introduction
    • Becker A, Bérubé D, Chad Z, Dolovich M, Ducharme F, D'Urzo T, Ernst P, Ferguson A, Gillespie C, Kapur S, et al; Canadian Network for Asthma Care; Canadian Thoracic Society. Canadian pediatric asthma consensus guidelines, 2003 (updated to December 2004): introduction. CMAJ 2005;173(6, Suppl)S12-S14.
    • (2005) CMAJ , vol.173 , Issue.6 and SUPPL.
    • Becker, A.1    Bérubé, D.2    Chad, Z.3    Dolovich, M.4    Ducharme, F.5    D'Urzo, T.6    Ernst, P.7    Ferguson, A.8    Gillespie, C.9    Kapur, S.10
  • 31
    • 33646471392 scopus 로고    scopus 로고
    • Inhaled corticosteroids for young children with wheezing
    • Gold DR, Fuhlbrigge AL. Inhaled corticosteroids for young children with wheezing. N Engl J Med 2006;354:2058-2060.
    • (2006) N Engl J Med , vol.354 , pp. 2058-2060
    • Gold, D.R.1    Fuhlbrigge, A.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.