-
1
-
-
33745211255
-
Antisense oligonucleotides: From design to therapeutic application
-
Chan, J. H., Lim, S., and Wong, W. S. (2006) Antisense oligonucleotides: from design to therapeutic application. Clin. Exp. Pharmacol. Physiol. 33, 533-40.
-
(2006)
Clin. Exp. Pharmacol. Physiol
, vol.33
, pp. 533-540
-
-
Chan, J.H.1
Lim, S.2
Wong, W.S.3
-
2
-
-
34447559636
-
Interfering with disease: A progress report on siRNA-based therapeutics
-
de Fougerolles, A., Vornlocher, H. P., Maraganore, J., and Lieberman, J. (2007) Interfering with disease: a progress report on siRNA-based therapeutics. Nat. Rev. Drug Discovery 6, 443-53.
-
(2007)
Nat. Rev. Drug Discovery
, vol.6
, pp. 443-453
-
-
de Fougerolles, A.1
Vornlocher, H.P.2
Maraganore, J.3
Lieberman, J.4
-
3
-
-
1542269161
-
Progress in antisense technology
-
Crooke, S. T. (2004) Progress in antisense technology. Annu. Rev. Med. 55, 61-95.
-
(2004)
Annu. Rev. Med
, vol.55
, pp. 61-95
-
-
Crooke, S.T.1
-
4
-
-
33847036990
-
Strategies for silencing human disease using RNA interference
-
Kim, D. H., and Rossi, J. J. (2007) Strategies for silencing human disease using RNA interference. Nat. Rev. Genet. 8, 173-84.
-
(2007)
Nat. Rev. Genet
, vol.8
, pp. 173-184
-
-
Kim, D.H.1
Rossi, J.J.2
-
5
-
-
35348861314
-
Cellular uptake and intracellular release are major obstacles to the therapeutic application of siRNA: Novel options by phosphorothioate-stimulated delivery
-
Mescalchin, A., Detzer, A., Wecke, M., Overhoff, M., Wunsche, W., and Sczakiel, G. (2007) Cellular uptake and intracellular release are major obstacles to the therapeutic application of siRNA: novel options by phosphorothioate-stimulated delivery. Exp. Opin. Biol. Ther. 7, 1531-8.
-
(2007)
Exp. Opin. Biol. Ther
, vol.7
, pp. 1531-1538
-
-
Mescalchin, A.1
Detzer, A.2
Wecke, M.3
Overhoff, M.4
Wunsche, W.5
Sczakiel, G.6
-
6
-
-
34249077607
-
Cell and tissue targeting of nucleic acids for cancer gene therapy
-
Russ, V., and Wagner, E. (2007) Cell and tissue targeting of nucleic acids for cancer gene therapy. Pharm. Res. 24, 1047-57.
-
(2007)
Pharm. Res
, vol.24
, pp. 1047-1057
-
-
Russ, V.1
Wagner, E.2
-
7
-
-
34648831747
-
Targeted quantum dot conjugates for siRNA delivery
-
Derfus, A. M., Chen, A. A., Min, D. H., Ruoslahti, E., and Bhatia, S. N. (2007) Targeted quantum dot conjugates for siRNA delivery. Bioconjugate Chem. 18, 1391-6.
-
(2007)
Bioconjugate Chem
, vol.18
, pp. 1391-1396
-
-
Derfus, A.M.1
Chen, A.A.2
Min, D.H.3
Ruoslahti, E.4
Bhatia, S.N.5
-
8
-
-
1942534976
-
Smart delivery of antisense oligonucleotides by anionic pH-sensitive uposomes
-
Fattal, E., Couvreur, P., and Dubernet, C. (2004) "Smart" delivery of antisense oligonucleotides by anionic pH-sensitive uposomes. Adv. Drug Delivery Rev. 56, 931-46.
-
(2004)
Adv. Drug Delivery Rev
, vol.56
, pp. 931-946
-
-
Fattal, E.1
Couvreur, P.2
Dubernet, C.3
-
9
-
-
33646685202
-
Delivery strategies for siRNA-mediated gene silencing
-
Gilmore, I. R., Fox, S. P., Hollins, A. J., and Akhtar, S. (2006) Delivery strategies for siRNA-mediated gene silencing. Curr. Drug Delivery 3, 147-5.
-
(2006)
Curr. Drug Delivery
, vol.3
, pp. 147-155
-
-
Gilmore, I.R.1
Fox, S.P.2
Hollins, A.J.3
Akhtar, S.4
-
10
-
-
33847099637
-
Lipid-based nanoparticles for nucleic acid delivery
-
Li, W., and Szoka, F. C., Jr. (2007) Lipid-based nanoparticles for nucleic acid delivery. Pharm. Res. 24, 438-49.
-
(2007)
Pharm. Res
, vol.24
, pp. 438-449
-
-
Li, W.1
Szoka Jr., F.C.2
-
11
-
-
42449089833
-
Strategies for in vivo siRNA delivery in cancer
-
Sanguino, A., Lopez-Berestein, G., and Sood, A. K. (2008) Strategies for in vivo siRNA delivery in cancer. Mini Rev. Med. Chem. 8, 248-55.
-
(2008)
Mini Rev. Med. Chem
, vol.8
, pp. 248-255
-
-
Sanguino, A.1
Lopez-Berestein, G.2
Sood, A.K.3
-
12
-
-
0842263616
-
Nanogels for oligonucleotide delivery to the brain
-
Vinogradov, S. V., Batrakova, E. V., and Kabanov, A. V. (2004) Nanogels for oligonucleotide delivery to the brain. Bioconjugate Chem. 15, 50-60.
-
(2004)
Bioconjugate Chem
, vol.15
, pp. 50-60
-
-
Vinogradov, S.V.1
Batrakova, E.V.2
Kabanov, A.V.3
-
13
-
-
33847020791
-
Peptide-based delivery of nucleic acids: Design, mechanism of uptake and applications to splice-correcting oligonucleotides
-
Abes, S., Moulton, H., Turner, J., Clair, P., Richard, J. P., Iversen, P., Gait, M. J., and Lebleu, B. (2007) Peptide-based delivery of nucleic acids: design, mechanism of uptake and applications to splice-correcting oligonucleotides. Biochem. Soc. Trans. 35, 53-5.
-
(2007)
Biochem. Soc. Trans
, vol.35
, pp. 53-55
-
-
Abes, S.1
Moulton, H.2
Turner, J.3
Clair, P.4
Richard, J.P.5
Iversen, P.6
Gait, M.J.7
Lebleu, B.8
-
14
-
-
17144395917
-
Peptide-oligonucleotide conjugates for the delivery of antisense and siRNA
-
Juliano, R. L. (2005) Peptide-oligonucleotide conjugates for the delivery of antisense and siRNA. Curr. Opin. Mol. Ther. 7, 132-6.
-
(2005)
Curr. Opin. Mol. Ther
, vol.7
, pp. 132-136
-
-
Juliano, R.L.1
-
15
-
-
43349103903
-
Intracellular delivery of an anionic antisense oligonucleotide via receptor-mediated endocytosis
-
Alam, M. R., Dixit, V., Kang, H., Li, Z. B., Chen, X., Trejo, J., Fisher, M., and Juliano, R. L. (2008) Intracellular delivery of an anionic antisense oligonucleotide via receptor-mediated endocytosis. Nucleic Acids Res. 36, 2764-76.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 2764-2776
-
-
Alam, M.R.1
Dixit, V.2
Kang, H.3
Li, Z.B.4
Chen, X.5
Trejo, J.6
Fisher, M.7
Juliano, R.L.8
-
16
-
-
36849081485
-
Insulin receptor substrate 1 knockdown in human MCF7 ER+ breast cancer cells by nuclease-resistant 1RS1 siRNA conjugated to a disulfide-bridged D-peptide analogue of insulin-like growth factor 1
-
Cesarone, G., Edupuganti, O. P., Chen, C. P., and Wickstrom, E. (2007) Insulin receptor substrate 1 knockdown in human MCF7 ER+ breast cancer cells by nuclease-resistant 1RS1 siRNA conjugated to a disulfide-bridged D-peptide analogue of insulin-like growth factor 1. Bioconjugate Chem. 18, 1831-40.
-
(2007)
Bioconjugate Chem
, vol.18
, pp. 1831-1840
-
-
Cesarone, G.1
Edupuganti, O.P.2
Chen, C.P.3
Wickstrom, E.4
-
17
-
-
0033302303
-
Transport of molecules, particles, and cells in solid tumors
-
Jain, R. K. (1999) Transport of molecules, particles, and cells in solid tumors. Annu. Rev. Biomed. Eng. 1, 241-63.
-
(1999)
Annu. Rev. Biomed. Eng
, vol.1
, pp. 241-263
-
-
Jain, R.K.1
-
18
-
-
0036386857
-
Transendothelial transport: The vesicle controversy
-
Rippe, B., Rosengren, B. I., Carlsson, O., and Venturoli, D. (2002) Transendothelial transport: the vesicle controversy. J. Vasc. Res. 39, 375-90.
-
(2002)
J. Vasc. Res
, vol.39
, pp. 375-390
-
-
Rippe, B.1
Rosengren, B.I.2
Carlsson, O.3
Venturoli, D.4
-
19
-
-
0001200347
-
In vivo behavior of liposomes; interaction with the mononuclear phagocyte system and implications for drug targeting
-
Juliano, R. L. Ed, Springer Verlag, Berlin
-
Scherphof G. L. (1991) In vivo behavior of liposomes; interaction with the mononuclear phagocyte system and implications for drug targeting, In Targeted Drug Delivery (Juliano, R. L. Ed.), Springer Verlag, Berlin.
-
(1991)
Targeted Drug Delivery
-
-
Scherphof, G.L.1
-
20
-
-
0033046220
-
Mechanisms of phagocytosis in macrophages
-
Aderem, A., and Underhill, D. M. (1999) Mechanisms of phagocytosis in macrophages. Annu. Rev. Immunol. 17, 593-623.
-
(1999)
Annu. Rev. Immunol
, vol.17
, pp. 593-623
-
-
Aderem, A.1
Underhill, D.M.2
-
21
-
-
34250819325
-
Poly(ethylene glycol)-modified nanocarriers for tumor-targeted and intracellular delivery
-
van Vlerken, L. E., Vyas, T. K., and Amiji, M. M. (2007) Poly(ethylene glycol)-modified nanocarriers for tumor-targeted and intracellular delivery. Pharm. Res. 24, 1405-14.
-
(2007)
Pharm. Res
, vol.24
, pp. 1405-1414
-
-
van Vlerken, L.E.1
Vyas, T.K.2
Amiji, M.M.3
-
22
-
-
0031300863
-
Pharmacokinetics of oligonucleotides
-
discussion 75-8
-
Agrawal, S., and Zhang, R. (1997) Pharmacokinetics of oligonucleotides. Ciba Found Symp. 209, 60-75, discussion 75-8.
-
(1997)
Ciba Found Symp
, vol.209
, pp. 60-75
-
-
Agrawal, S.1
Zhang, R.2
-
23
-
-
0027786912
-
Disposition of the 14C-labeled phosphorothioate oligonucleotide ISIS 2105 after intravenous administration to rats
-
Cossum, P. A., Sasmor, H., Dellinger, D., Truong, L., Cummins, L., Owens, S. R., Markham, P. M., Shea, J. P., and Crooke, S. (1993) Disposition of the 14C-labeled phosphorothioate oligonucleotide ISIS 2105 after intravenous administration to rats. J. Pharmacol. Exp. Ther. 267, 1181-90.
-
(1993)
J. Pharmacol. Exp. Ther
, vol.267
, pp. 1181-1190
-
-
Cossum, P.A.1
Sasmor, H.2
Dellinger, D.3
Truong, L.4
Cummins, L.5
Owens, S.R.6
Markham, P.M.7
Shea, J.P.8
Crooke, S.9
-
24
-
-
0030943935
-
Comparative pharmacokinetics, tissue distribution, and tumor accumulation of phosphorothioate, phosphorodithioate, and methylphosphonate oligonucleotides in nude mice
-
DeLong, R. K., Nolting, A., Fisher, M., Chen, Q., Wickstrom, E., Kligshteyn, M., Demirdji, S., Caruthers, M., and Juliano, R. L. (1997) Comparative pharmacokinetics, tissue distribution, and tumor accumulation of phosphorothioate, phosphorodithioate, and methylphosphonate oligonucleotides in nude mice. Antisense Nucleic Acid Drug Dev. 7, 71-7.
-
(1997)
Antisense Nucleic Acid Drug Dev
, vol.7
, pp. 71-77
-
-
DeLong, R.K.1
Nolting, A.2
Fisher, M.3
Chen, Q.4
Wickstrom, E.5
Kligshteyn, M.6
Demirdji, S.7
Caruthers, M.8
Juliano, R.L.9
-
25
-
-
34547167416
-
Pharmacokinetics, biodistribution, stability and toxicity of a cell-penetrating peptide-morpholino oligomer conjugate
-
Amantana, A., Moulton, H. M., Cate, M. L., Reddy, M. T., Whitehead, T., Hassinger, J. N., Youngblood, D. S., and Iversen, P. L. (2007) Pharmacokinetics, biodistribution, stability and toxicity of a cell-penetrating peptide-morpholino oligomer conjugate. Bioconjugate Chem. 18, 1325-31.
-
(2007)
Bioconjugate Chem
, vol.18
, pp. 1325-1331
-
-
Amantana, A.1
Moulton, H.M.2
Cate, M.L.3
Reddy, M.T.4
Whitehead, T.5
Hassinger, J.N.6
Youngblood, D.S.7
Iversen, P.L.8
-
27
-
-
0141497030
-
Therapeutic potential of antisense oligonucleotides as modulators of alternative splicing
-
Sazani, P., and Kole, R. (2003) Therapeutic potential of antisense oligonucleotides as modulators of alternative splicing. J. Clin. Invest. 112, 481-6.
-
(2003)
J. Clin. Invest
, vol.112
, pp. 481-486
-
-
Sazani, P.1
Kole, R.2
-
28
-
-
38549140211
-
Doxorubicin coupled to lactosaminated albumin: Effect of heterogeneity in drug load on conjugate disposition and hepatocellular carcinoma uptake in rats
-
Di Stefano, G., Fiume, L., Baglioni, M., Busi, C., Bolondi, L., Farina, C., Mori, F., Chieco, P., Pariali, M., Kratz, F., Molin, L., Salmaso, S., and Cahceti, P. (2008) Doxorubicin coupled to lactosaminated albumin: effect of heterogeneity in drug load on conjugate disposition and hepatocellular carcinoma uptake in rats. Eur. J. Pharm. Sci. 33, 191-8.
-
(2008)
Eur. J. Pharm. Sci
, vol.33
, pp. 191-198
-
-
Di Stefano, G.1
Fiume, L.2
Baglioni, M.3
Busi, C.4
Bolondi, L.5
Farina, C.6
Mori, F.7
Chieco, P.8
Pariali, M.9
Kratz, F.10
Molin, L.11
Salmaso, S.12
Cahceti, P.13
-
29
-
-
35548959504
-
Improved efficacy of αvβ3-targeted albumin conjugates by conjugation of a novel auristatin derivative
-
Temming, K., Meyer, D. L., Zabinski, R., Senter, P. D., Poelstra, K., Molema, G., and Kok, R. J. (2007) Improved efficacy of αvβ3-targeted albumin conjugates by conjugation of a novel auristatin derivative. Mol. Pharm. 4, 686-94.
-
(2007)
Mol. Pharm
, vol.4
, pp. 686-694
-
-
Temming, K.1
Meyer, D.L.2
Zabinski, R.3
Senter, P.D.4
Poelstra, K.5
Molema, G.6
Kok, R.J.7
-
30
-
-
24944523300
-
Clathrin-independent endocytosis: New insights into caveolae and non-caveolar lipid raft carriers
-
Kirkham, M., and Parton, R. G. (2005) Clathrin-independent endocytosis: new insights into caveolae and non-caveolar lipid raft carriers. Biochim. Biophys. Acta 1745, 273-86.
-
(2005)
Biochim. Biophys. Acta
, vol.1745
, pp. 273-286
-
-
Kirkham, M.1
Parton, R.G.2
-
31
-
-
33645515261
-
Integrin trafficking and the control of cell migration
-
Caswell, P. T., and Norman, J. C. (2006) Integrin trafficking and the control of cell migration. Traffic 7, 14-21.
-
(2006)
Traffic
, vol.7
, pp. 14-21
-
-
Caswell, P.T.1
Norman, J.C.2
-
32
-
-
34248226275
-
αvβ3 and α5β1 integrin recychng pathways dictate downstream Rho kinase signaling to regulate persistent cell migration
-
White, D. P., Caswell, P. T., and Norman, J. C. (2007) αvβ3 and α5β1 integrin recychng pathways dictate downstream Rho kinase signaling to regulate persistent cell migration. J. Cell Biol. 177, 515-25.
-
(2007)
J. Cell Biol
, vol.177
, pp. 515-525
-
-
White, D.P.1
Caswell, P.T.2
Norman, J.C.3
-
33
-
-
44249097826
-
-
Ryan, S. M., Mantovani, G., Wang, X., Haddleton, D. M., and Brayden, D. J. (2008) Advances in PEGylation of important biotech molecules: delivery aspects. Expert Opin. Drug Delivery 5, 371-83.
-
Ryan, S. M., Mantovani, G., Wang, X., Haddleton, D. M., and Brayden, D. J. (2008) Advances in PEGylation of important biotech molecules: delivery aspects. Expert Opin. Drug Delivery 5, 371-83.
-
-
-
-
34
-
-
33746438424
-
Toxicity of cationic lipids and cationic polymers in gene delivery
-
Lv, H., Zhang, S., Wang, B., Cui, S., and Yan, J. (2006) Toxicity of cationic lipids and cationic polymers in gene delivery. J. Controlled Release 114, 100-9.
-
(2006)
J. Controlled Release
, vol.114
, pp. 100-109
-
-
Lv, H.1
Zhang, S.2
Wang, B.3
Cui, S.4
Yan, J.5
-
35
-
-
84890627971
-
Biological Barriers to Nanocarrier-Mediated Delivery of Therapeutic and Imaging Agents
-
Mirkin, C, and Niemeyer, C. Eds, pp, Wiley-VCH, Weinheim, Germany
-
Juliano, R. L. (2007) Biological Barriers to Nanocarrier-Mediated Delivery of Therapeutic and Imaging Agents, In Nanobiotechnology II (Mirkin, C., and Niemeyer, C. Eds.) pp 263-278, Wiley-VCH, Weinheim, Germany.
-
(2007)
Nanobiotechnology II
, pp. 263-278
-
-
Juliano, R.L.1
-
36
-
-
34547653668
-
Enhanced permeability and retention of macromolecular drugs in solid tumors: A royal gate for targeted anticancer nanomedicines
-
Greish, K. (2007) Enhanced permeability and retention of macromolecular drugs in solid tumors: a royal gate for targeted anticancer nanomedicines. J. Drug Targeting 15, 457-64.
-
(2007)
J. Drug Targeting
, vol.15
, pp. 457-464
-
-
Greish, K.1
|