Application of coherent anti-Stokes Raman scattering microscopy to image the changes in a paclitaxel-poly(styrene-b-isobutylene-b-styrene) matrix pre- and post-drug elution

Journal of Biomedical Materials Research - Part A

Volumn 87, Issue 4, 2008, Pages 913-920

  Kang, Eunah ^a   Wang, Haifeng ^a   Kwon, Il Keun ^c   Song, Young Ho ^d   Kamath, Kalpana ^d   Miller, Kathleen M ^d   Barry, James ^d   Cheng, Ji Xin ^a   Park, Kinam ^a,b  

^a PURDUE UNIVERSITY   (United States)

^b PURDUE UNIVERSITY   (United States)

^c Kyung Hee University   (South Korea)

^d BOSTON SCIENTIFIC CORPORATION   (United States)

Author keywords

Coherent anti Stokes Raman scattering (CARS); Drug eluting stent; Microscopy; Paclitaxel; Poly(styrene b isobutylene b styrene) (SIBS)

Indexed keywords

ABS RESINS; BUTENES; CHROMATOGRAPHIC ANALYSIS; DISSOLUTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MICROSCOPIC EXAMINATION; PLASTIC FILMS; POLYMER FILMS; POLYMERS; RAMAN SPECTROSCOPY; SCATTERING; STYRENE; THREE DIMENSIONAL;

COHERENT ANTI-STOKES RAMAN SCATTERING (CARS); DRUG-ELUTING STENT; MICROSCOPY; PACLITAXEL; POLY(STYRENE-B-ISOBUTYLENE-B-STYRENE) (SIBS);

RAMAN SCATTERING;

FW 854; PACLITAXEL; POLY(STYRENE B ISOBUTYLENE B STYRENE); POLYSTYRENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BIOFILM; COHERENT ANTISTOKES RAMAN SCATTERING MICROSCOPY; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG RELEASE; ELUTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; MICROSCOPY; MORPHOLOGY; POLYMERIZATION; QUANTITATIVE ANALYSIS; SCANNING ELECTRON MICROSCOPY; THREE DIMENSIONAL IMAGING;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BIOCOMPATIBLE MATERIALS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; MATERIALS TESTING; PACLITAXEL; POLYMERS; SPECTRUM ANALYSIS, RAMAN; STENTS; STYRENES; SURFACE PROPERTIES;

EID: 56749104304     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.31813     Document Type: Article

References (26)

1. Edelman ER, Rogers C. Pathobiologic responses to stenting. Am J Cardiol 1998;81:4E-6E.
2. Torres K, Horwitz SB. Mechanisms of Taxol-induced cell death are concentration dependent. Cancer Res 1998;58:3620-3626.
3. Hwang CW, Wu D, Edelman ER. Stent-based delivery is associated with marked spatial variations in drug distribution. J Am Coll Cardiol 2001;37(2):1A-2A.
4. Finkelstein A, McClean D, Kar S, Takizawa K, Varghese K, Baek N, Park K, Fishbein MC, Makkar R, Litvack F, Eigler NL. Local drug delivery via a coronary stent with programmable release pharmacokinetics. Circulation 2003;107: 777-784.
5. Westedt U, Wittmar M, Hellwig M, Hanefeld P, Greiner A, Schaper AK, Kissel T. Paclitaxel releasing films consisting of poly(vinyl alcohol)-graft-poly(lactide-co-glycolide) and their potential as biodegradable stent coatings. J Control Release 2006;111:235-246.
6. Acharya G, Park K. Mechanism of controlled drug release from drug-eluting stents. Adv Drug Delivery Rev 2006;58: 387-401.
7. van der Weerd J, Kazarian SG. Combined approach of FTIR imaging and conventional dissolution tests applied to drug release. J Control Release 2004;98:295-305.
8. Bobiak JP, Koenig JL. Regions of interest in FTIR imaging applications: Diffusion of nicotine into ethylene-co-vinyl acetate films. J Control Release 2005;106:329-338.
9. Coutts-Lendon C, Koenig JL. Investigation of the aqueous dissolution of semicrystalline poly(ethylene oxide) using infrared chemical imaging: The effects of molecular weight and crystallinity. Appl Specteosc 2005;59:976-985.
10. Feofanov AV, Grichine AI, Shitova LA, Karmakova TA, Yakubovskaya RI, Egret-Charlier M, Vigny P. Confocal Raman microspectroscopy and imaging study of theraphthal in living cancer cells. Biophys J 2000;78:499-512.
11. Wartewig S, Neubert RHH. Pharmaceutical applications of mid-IR and Raman spectroscopy. Adv Drug Delivery Rev 2005;57:1144-1170.
12. Ashraf M, Iuorno VL, Coffinbeach D, Evans CA, Augsburger LL. A novel nuclear-magnetic-resonance (NMR) imaging method for measuring the water front penetration rate in hydrophilic polymer matrix capsule plugs and its role in drug-release. Pharm Res 1994;11:733-737.
13. Verhoeven M, Driessen AAG, Paul AJ, Brown A, Canry JC, Hendriks M. DSIMS characterization of a drug-containing polymer-coated cardiovascular stent. J Control Release 2004; 96:113-121.
14. Belu AM, Davies MC, Newton JM, Patel N. TOF-SIMS characterization and imaging of controlled-release drug delivery systems. Anal Chem 2000;72:5625-5638.
15. Kang E, Wang H, Kwon IK, Robinson J, Park K, Cheng J-X. In situ visualization of paclitaxel distribution and release by coherent anti-Stokes Raman scattering microscopy. Anal Chem 2006;78:8036-8043.
16. Cheng JX, Xie XS. Coherent anti-Stokes Raman scattering microscopy: Instrumentation, theory, and applications. J Phys Chem B 2004;108:827-840.
17. Cheng JX. Coherent anti-Stokes Raman scattering microscopy. Appl Spectoosc 2007;61:197A-208A.
18. Ranade SV, Miller KM, Richard RE, Chan AK, Allen MJ, Helmus MN. Physical characterization of controlled release of paclitaxel from the TAXUS™ Express2™ drug-eluting stent. J Biomed Mater Res A 2004;71:625-634.
19. Ranade SV, Richard RE, Helmus MN. Styrenic block copolymers for biomaterial and drug delivery applications. Acta Biomater 2005;1:134-144.
20. Kamath KR, Barry JJ, Miller KM. The Taxus drug-eluting stent: A new paradigm in controlled drug delivery. Adv Drug Delivery Rev 2006;58:412-436.
21. Cheng JX, Jia KY, Zheng G, Xie XS. Laser-scanning coherent anti-Stokes Raman scattering microscopy and applications to cell biology. Biophys J 2002;83:502-509.
22. Li L, Wang H, Cheng JX. Quantitative coherent anti-Stokes Raman scattering imaging of lipid distribution in co-existing domains. Biophys J 2005;89:3480-3490.
23. Coutts-Lendon CA, Wright NA, Mieso EV, Koenig JL. The use of FT-IR imaging as an analytical tool for the characterization of drug delivery systems. J Control Release 2003;93:223-248.
24. Siepmann J, Streubel A, Peppas NA. Understanding and predicting drug delivery from hydrophilic matrix tablets using the "sequential layer" model. Pharm Res 2002;19:306-314.
25. Siepmann J, Peppas NA. Modeling of drug release from delivery systems based on hydroxypropyl methylcellulose (HPMC). Adv Drug Delivery Rev 2001;48(2/3):139-157.
26. Siepmann J, Faisant N, Benoit JP. A new mathematical model quantifying drug release from bioerodible microparticles using Monte Carlo simulations. Pharm Res 2002;19:1885-1893.