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Volumn 34, Issue 10, 2008, Pages 710-714

The ethics of paediatric anti-depressant use: Erring on the side of caution

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; FLUOXETINE; SEROTONIN UPTAKE INHIBITOR;

EID: 56749104280     PISSN: 03066800     EISSN: 14734257     Source Type: Journal    
DOI: 10.1136/jme.2007.023119     Document Type: Review
Times cited : (5)

References (56)
  • 1
    • 24644494320 scopus 로고    scopus 로고
    • Treatment of depression in children and adolescents
    • Ryan RD. Treatment of depression in children and adolescents. Lancet 2005;366:933-40.
    • (2005) Lancet , vol.366 , pp. 933-940
    • Ryan, R.D.1
  • 2
    • 0033749614 scopus 로고    scopus 로고
    • The challenge of diagnosing depression in childhood and adolescence
    • Carlson GA. The challenge of diagnosing depression in childhood and adolescence. J Affect Disorders 2000;61(Suppl):3-8.
    • (2000) J Affect Disorders , vol.61 , Issue.SUPPL. , pp. 3-8
    • Carlson, G.A.1
  • 3
    • 0034062880 scopus 로고    scopus 로고
    • A review of pharmacotherapy of major depression in children and adolescents
    • Ambrosini PJ. A review of pharmacotherapy of major depression in children and adolescents. Psychiat Serv 2000;51:627-33.
    • (2000) Psychiat Serv , vol.51 , pp. 627-633
    • Ambrosini, P.J.1
  • 4
    • 79959924856 scopus 로고    scopus 로고
    • Depression in children and young people: Identification and management in primary, community and secondary care
    • NHS National Institute for Health and Clinical Excellence NICE, September, accessed 18 Jul 2008
    • NHS National Institute for Health and Clinical Excellence (NICE). Depression in children and young people: identification and management in primary, community and secondary care. NICE Clinical Guideline 28. September 2005. http://www.nice.org.uk/CG028 (accessed 18 Jul 2008).
    • (2005) NICE Clinical Guideline , vol.28
  • 5
    • 56749108371 scopus 로고    scopus 로고
    • European Medicines Agency adopts a positive opinion for the use of Prozac in the treatment of children and adolescents suffering from depression
    • 6 June 2006, accessed 18 Jul 2008
    • European Medicines Agency. European Medicines Agency adopts a positive opinion for the use of Prozac in the treatment of children and adolescents suffering from depression. Press Release 6 June 2006. http://www.emea.europa.eu/pdfs/human/press/pr/20255406en.pdf (accessed 18 Jul 2008).
    • Press Release
  • 6
    • 10644286437 scopus 로고    scopus 로고
    • Rethinking childhood depression
    • Timimi S. Rethinking childhood depression. BMJ 2004;329:1394-6.
    • (2004) BMJ , vol.329 , pp. 1394-1396
    • Timimi, S.1
  • 7
    • 56749099195 scopus 로고    scopus 로고
    • Hansard. Written answers, House of Commons, 19 July 2007, Column 536W.
    • Hansard. Written answers, House of Commons, 19 July 2007, Column 536W.
  • 8
    • 9644275416 scopus 로고    scopus 로고
    • Increased prescribing trends of paediatric psychotropic medications
    • Wong ICK, Murray ML, Camilleri-Novak D, et al. Increased prescribing trends of paediatric psychotropic medications. Arch Dis Child 2004;89:1131-2.
    • (2004) Arch Dis Child , vol.89 , pp. 1131-1132
    • Wong, I.C.K.1    Murray, M.L.2    Camilleri-Novak, D.3
  • 9
    • 1842638639 scopus 로고    scopus 로고
    • Efficacy and safety of antidepressants for children and adolescents
    • Jureidini JN, Doecke CJ, Mansfield PR, et al. Efficacy and safety of antidepressants for children and adolescents. BMJ 2004;328:879-83.
    • (2004) BMJ , vol.328 , pp. 879-883
    • Jureidini, J.N.1    Doecke, C.J.2    Mansfield, P.R.3
  • 10
    • 4043156247 scopus 로고    scopus 로고
    • Fluoxetine, cognitive-behavioral therapy, and their combination for adolescents with depression
    • March J, Silva S, Petrycki S, et al. Fluoxetine, cognitive-behavioral therapy, and their combination for adolescents with depression. JAMA 2004;292:807-20.
    • (2004) JAMA , vol.292 , pp. 807-820
    • March, J.1    Silva, S.2    Petrycki, S.3
  • 11
    • 34447643758 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibitors (SSRIs) and routine specialist care with and without cognitive-behavioural therapy in adolescents with major depression: Randomised controlled trial
    • Goodyer I, Dubicka B, Wilkinson P, et al. Selective serotonin reuptake inhibitors (SSRIs) and routine specialist care with and without cognitive-behavioural therapy in adolescents with major depression: randomised controlled trial. BMJ 2007;335:142-6.
    • (2007) BMJ , vol.335 , pp. 142-146
    • Goodyer, I.1    Dubicka, B.2    Wilkinson, P.3
  • 12
    • 56749141630 scopus 로고    scopus 로고
    • Re:Re:Re: Fluoxetine for depressed adolescents: harms likely to exceed benefits
    • 25 May 2007, accessed 23 August 2007, LV CHECK AGAIN, not working
    • Kozart M. Re:Re:Re: Fluoxetine for depressed adolescents: harms likely to exceed benefits. BMJ Rapid Responses 25 May 2007. http://www.bmj.com/cgi/eletters/330/7493/730-b (accessed 23 August 2007). LV CHECK AGAIN, not working
    • BMJ Rapid Responses
    • Kozart, M.1
  • 13
    • 34547893879 scopus 로고    scopus 로고
    • Study was not a trial of antidepressants
    • Jureidini JN. Study was not a trial of antidepressants. BMJ 2007;335:221.
    • (2007) BMJ , vol.335 , pp. 221
    • Jureidini, J.N.1
  • 14
    • 4143090320 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibitor-induced sexual dysfunction in adolescents: A review
    • Scharko AM. Selective serotonin reuptake inhibitor-induced sexual dysfunction in adolescents: a review. J Am Acad Adolesc Psychiat 2004;43:1071-9.
    • (2004) J Am Acad Adolesc Psychiat , vol.43 , pp. 1071-1079
    • Scharko, A.M.1
  • 15
    • 3242760520 scopus 로고    scopus 로고
    • Volatile chemistry: Children and antidepressants
    • Couzin J. Volatile chemistry: children and antidepressants. Science 2004;305:468-70.
    • (2004) Science , vol.305 , pp. 468-470
    • Couzin, J.1
  • 16
    • 0141638673 scopus 로고    scopus 로고
    • Antidepressants and suicide: Risk-benefit conundrums
    • Healy D, Whitaker C. Antidepressants and suicide: risk-benefit conundrums. J Psychiat Neurosci 2003;28:331-7.
    • (2003) J Psychiat Neurosci , vol.28 , pp. 331-337
    • Healy, D.1    Whitaker, C.2
  • 17
    • 33644600647 scopus 로고    scopus 로고
    • The SSRI trials in children: Disturbing implications for academic medicine
    • Leo J. The SSRI trials in children: disturbing implications for academic medicine. Ethical Hum Psychol Psychiat 2006;8:29-41.
    • (2006) Ethical Hum Psychol Psychiat , vol.8 , pp. 29-41
    • Leo, J.1
  • 18
    • 1942468862 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibitors in childhood depression: Systematic review of published versus unpublished data
    • Whittington CJ, Kendell T, Fonagy P, et al. Selective serotonin reuptake inhibitors in childhood depression: systematic review of published versus unpublished data. Lancet 2004;363:1341-5.
    • (2004) Lancet , vol.363 , pp. 1341-1345
    • Whittington, C.J.1    Kendell, T.2    Fonagy, P.3
  • 19
    • 56749113142 scopus 로고    scopus 로고
    • US antidepressants to carry suicide warnings
    • 18 October, doi:10.1038/news041018-2
    • Check E. US antidepressants to carry suicide warnings. news@nature.com 18 October 2004. doi:10.1038/news041018-2.
    • (2004) news@nature.com
    • Check, E.1
  • 20
    • 56749135050 scopus 로고    scopus 로고
    • Prozac 20mg hard capsules
    • and Company Limited, 21 August, From MRHA 8 August
    • Eli Lilly and Company Limited. Prozac 20mg hard capsules. Product information sheet PL 00006/0195, 21 August 2006. From MRHA 8 August, 2007.
    • (2006) Product information sheet PL 00006/0195
    • Lilly, E.1
  • 21
    • 33645017141 scopus 로고    scopus 로고
    • Brain development during puberty: State of the science
    • Blakemore S-J, Choudhury S. Brain development during puberty: state of the science. Developmental Sci 2006;9:11-14.
    • (2006) Developmental Sci , vol.9 , pp. 11-14
    • Blakemore, S.-J.1    Choudhury, S.2
  • 22
    • 4544296214 scopus 로고    scopus 로고
    • Altering the course of neurodevelopment: A framework for understanding the enduring effects of psychotropic drugs
    • Andersen SL, Navalta CP. Altering the course of neurodevelopment: a framework for understanding the enduring effects of psychotropic drugs. Int J Dev Neurosci 2004;22:423-40.
    • (2004) Int J Dev Neurosci , vol.22 , pp. 423-440
    • Andersen, S.L.1    Navalta, C.P.2
  • 23
    • 7444232259 scopus 로고    scopus 로고
    • Early-life blockade of the 5HT transporter alters emotional behavior in adult mice
    • Ansorge MS, Zhou M, Lira A, et al. Early-life blockade of the 5HT transporter alters emotional behavior in adult mice. Science 2004;306:879-81.
    • (2004) Science , vol.306 , pp. 879-881
    • Ansorge, M.S.1    Zhou, M.2    Lira, A.3
  • 24
    • 33846786700 scopus 로고    scopus 로고
    • Adolescent fluoxetine exposure produces enduring, sex-specific alterations of visual discrimination and attention in rats
    • LaRoche RB, Morgan RE. Adolescent fluoxetine exposure produces enduring, sex-specific alterations of visual discrimination and attention in rats. Neurotoxicol Teratol 2007;29:96-107.
    • (2007) Neurotoxicol Teratol , vol.29 , pp. 96-107
    • LaRoche, R.B.1    Morgan, R.E.2
  • 25
    • 32844459497 scopus 로고    scopus 로고
    • Neonatal antidepressant exposure has lasting effects on behavior and serotonin circuitry
    • Maciag D, Simpson KL, Coppinger D, et al. Neonatal antidepressant exposure has lasting effects on behavior and serotonin circuitry. Neuropsycopharmacology 2006;31:47-57.
    • (2006) Neuropsycopharmacology , vol.31 , pp. 47-57
    • Maciag, D.1    Simpson, K.L.2    Coppinger, D.3
  • 26
    • 0034680978 scopus 로고    scopus 로고
    • Chronic fluoxetine administration to juvenile rats prevents age-associated dendritic spine formation in hippocampus
    • Norrholm SD, Ouimet CC. Chronic fluoxetine administration to juvenile rats prevents age-associated dendritic spine formation in hippocampus. Brain Res 2000;883:205-15.
    • (2000) Brain Res , vol.883 , pp. 205-215
    • Norrholm, S.D.1    Ouimet, C.C.2
  • 27
    • 12344313055 scopus 로고    scopus 로고
    • Inhibition of the serotonin (5-hydroxytryptamine) transporter reduces bone accrual during growth
    • Warden SJ, Robling AG, Sanders MS, et al. Inhibition of the serotonin (5-hydroxytryptamine) transporter reduces bone accrual during growth. Endocrinology 2005;146:658-93.
    • (2005) Endocrinology , vol.146 , pp. 658-693
    • Warden, S.J.1    Robling, A.G.2    Sanders, M.S.3
  • 28
    • 8144226482 scopus 로고    scopus 로고
    • Safety of subchronic treatment with fluoxetine for major depressive disorder in children and adolescents
    • Nilsson M, Joliat MJ, Miner CM, et al. Safety of subchronic treatment with fluoxetine for major depressive disorder in children and adolescents. J Child Adolesc Psychopharmaol 2000;14:412-17.
    • (2000) J Child Adolesc Psychopharmaol , vol.14 , pp. 412-417
    • Nilsson, M.1    Joliat, M.J.2    Miner, C.M.3
  • 29
    • 0036315424 scopus 로고    scopus 로고
    • Decreased growth during therapy with selective serotonin reuptake inhibitors
    • Weintrob N, Cohen D, Klipper-Aurbach Y, et al. Decreased growth during therapy with selective serotonin reuptake inhibitors. Arch Pediatr Adolesc Med 2002:156:696-701.
    • (2002) Arch Pediatr Adolesc Med , vol.156 , pp. 696-701
    • Weintrob, N.1    Cohen, D.2    Klipper-Aurbach, Y.3
  • 30
    • 56749141623 scopus 로고    scopus 로고
    • Depression in children and young people: Understanding NICE guidance - information for children and young people with depression, their families and carers, and the public
    • National Institute for Health and Clinical Excellence NICE, September, accessed 18 Jul 2008
    • National Institute for Health and Clinical Excellence (NICE). Depression in children and young people: Understanding NICE guidance - information for children and young people with depression, their families and carers, and the public. Information about NICE Clinical Guideline 28. September 2005. http://www.nice.org.uk/guidance/index.jsp?action=byID&o= 10970 (accessed 18 Jul 2008).
    • (2005) Information about NICE Clinical Guideline , vol.28
  • 31
    • 56749139057 scopus 로고    scopus 로고
    • Cheshire and Wirral Partnership NHS Trust. Fluoxetine: antidepressant medication for children and young people - Information for parents and carers. February 2006. Code: D-AD-06-014. Available from Cheshire and Wirral Partnership NHS Trust, Upton Lea, Countess of Chester Health Park, Liverpool Road, Chester CH2 1BQ.
    • Cheshire and Wirral Partnership NHS Trust. Fluoxetine: antidepressant medication for children and young people - Information for parents and carers. February 2006. Code: D-AD-06-014. Available from Cheshire and Wirral Partnership NHS Trust, Upton Lea, Countess of Chester Health Park, Liverpool Road, Chester CH2 1BQ.
  • 33
    • 0029876823 scopus 로고    scopus 로고
    • Antidepressants for children. Is scientific support necessary?
    • Fisher RL, Fisher S. Antidepressants for children. Is scientific support necessary? J Nerv Ment Dis 1996;184:99-102.
    • (1996) J Nerv Ment Dis , vol.184 , pp. 99-102
    • Fisher, R.L.1    Fisher, S.2
  • 34
    • 33644600647 scopus 로고    scopus 로고
    • The SSRI trials in children: Disturbing implications for academic medicine
    • Leo J. The SSRI trials in children: disturbing implications for academic medicine. Ethical Hum Psychol Psychiat 2006;8:29-41.
    • (2006) Ethical Hum Psychol Psychiat , vol.8 , pp. 29-41
    • Leo, J.1
  • 36
    • 34548152773 scopus 로고    scopus 로고
    • Is depression overdiagnosed? Yes
    • Parker G. Is depression overdiagnosed? Yes. BMJ 2007;355:328.
    • (2007) BMJ , vol.355 , pp. 328
    • Parker, G.1
  • 37
    • 0034153795 scopus 로고    scopus 로고
    • Pursued by happiness and beaten senseless: Prozac and the American Dream
    • Elliott C. Pursued by happiness and beaten senseless: Prozac and the American Dream. Hastings Cent Rep 2000;30:7-12.
    • (2000) Hastings Cent Rep , vol.30 , pp. 7-12
    • Elliott, C.1
  • 38
    • 56749147079 scopus 로고    scopus 로고
    • How do we tackle the rise in the number of children on antidepressants?
    • 12 Aug 2007, accessed 18 Jul 2008, Anon
    • Anon. How do we tackle the rise in the number of children on antidepressants? Independent 12 Aug 2007. http://news.independent.co.uk/ health/article2851984.ece (accessed 18 Jul 2008).
    • Independent
  • 39
    • 26944442446 scopus 로고    scopus 로고
    • US teenager's parents sue school over depression screening test
    • Lenzer J. US teenager's parents sue school over depression screening test. BMJ 2005;331:714.
    • (2005) BMJ , vol.331 , pp. 714
    • Lenzer, J.1
  • 40
    • 3543024785 scopus 로고    scopus 로고
    • Depression in children
    • Gotlib IH, Hammen CL, eds, London: Guilford Press
    • Garber J, Horowitz JL. Depression in children. In: Gotlib IH, Hammen CL, eds. Handbook of depression. London: Guilford Press, 2002:539.
    • (2002) Handbook of depression , pp. 539
    • Garber, J.1    Horowitz, J.L.2
  • 41
    • 1642284035 scopus 로고    scopus 로고
    • Cognitive-behavioural treatment of depression
    • Gotlib IH, Hammen CL, eds, London: Guilford Press
    • Hollon SD, Haman KL, Brown LL. Cognitive-behavioural treatment of depression. In: Gotlib IH, Hammen CL, eds. Handbook of depression. London: Guilford Press, 2002.
    • (2002) Handbook of depression
    • Hollon, S.D.1    Haman, K.L.2    Brown, L.L.3
  • 42
    • 20044370301 scopus 로고    scopus 로고
    • Antidepressants and children's depression
    • Diller L. Antidepressants and children's depression. Am J Psychiat 2005;162:1227.
    • (2005) Am J Psychiat , vol.162 , pp. 1227
    • Diller, L.1
  • 43
    • 0037640977 scopus 로고    scopus 로고
    • Child and adolescent depression: Short-term treatment effectiveness and long-term opportunities
    • Ryan ND. Child and adolescent depression: short-term treatment effectiveness and long-term opportunities. Int J Meth Psych Res 2006;12:44-53.
    • (2006) Int J Meth Psych Res , vol.12 , pp. 44-53
    • Ryan, N.D.1
  • 44
    • 3543024785 scopus 로고    scopus 로고
    • Depression in children
    • Gotlib IH, Hammen CL, eds, London: Guilford Press
    • Garber J, Horowitz JL. Depression in children. In: Gotlib IH, Hammen CL, eds. Handbook of depression. London: Guilford Press, 2002.
    • (2002) Handbook of depression
    • Garber, J.1    Horowitz, J.L.2
  • 45
    • 10644286437 scopus 로고    scopus 로고
    • Rethinking childhood depression
    • Timimi S. Rethinking childhood depression. BMJ 2004;329:1394-6.
    • (2004) BMJ , vol.329 , pp. 1394-1396
    • Timimi, S.1
  • 46
    • 56749120801 scopus 로고    scopus 로고
    • Science and Environmental Health Network SEHN, accessed 18 Jul 2007
    • Science and Environmental Health Network (SEHN). Wingspread conference on the precautionary principle. http://www.sehn.org/wing.html (accessed 18 Jul 2007).
    • Wingspread conference on the precautionary principle
  • 47
    • 0033615026 scopus 로고    scopus 로고
    • Precautionary principle stifles discovery
    • Holm S, Harris J. Precautionary principle stifles discovery. Nature 1999;400:398.
    • (1999) Nature , vol.400 , pp. 398
    • Holm, S.1    Harris, J.2
  • 48
    • 10044260970 scopus 로고    scopus 로고
    • The precautionary principle and medical decision making
    • Resnick DB. The precautionary principle and medical decision making. J Med Philos 2004;29:281-99.
    • (2004) J Med Philos , vol.29 , pp. 281-299
    • Resnick, D.B.1
  • 49
    • 33845392626 scopus 로고    scopus 로고
    • TADS Team. The treatment for adolescents with depression study (TADS): Methods and message at 12 weeks
    • March J, Silva S, Benedetto B, TADS Team. The treatment for adolescents with depression study (TADS): methods and message at 12 weeks. J Am Acad Child Adolesc Psychiatry 2006;45:1393-1403.
    • (2006) J Am Acad Child Adolesc Psychiatry , vol.45 , pp. 1393-1403
    • March, J.1    Silva, S.2    Benedetto, B.3
  • 50
    • 9644275416 scopus 로고    scopus 로고
    • Increased prescribing trends of paediatric psychotropic medications
    • Wong ICK, Murray ML, Camilleri-Novak D, et al. Increased prescribing trends of paediatric psychotropic medications. Arch Dis Child 2004;89:1131-2.
    • (2004) Arch Dis Child , vol.89 , pp. 1131-1132
    • Wong, I.C.K.1    Murray, M.L.2    Camilleri-Novak, D.3
  • 51
    • 56749118732 scopus 로고    scopus 로고
    • Banned depression tablets are still being prescribed to thousands of children
    • 13 Mar 2006, accessed 18 Jul 2008
    • Anon. Banned depression tablets are still being prescribed to thousands of children. Telegraph 13 Mar 2006. http://www.telegraph.co.uk/ health/main.jhtml?xml=/health/2006/03/13/nkidrugs12.xml (accessed 18 Jul 2008).
    • Telegraph
    • Anon1
  • 52
    • 56749147079 scopus 로고    scopus 로고
    • How do we tackle the rise in the number of children on antidepressants?
    • 12 Aug 2007, accessed 18 Jul 2008, Anon
    • Anon. How do we tackle the rise in the number of children on antidepressants? Independent 12 Aug 2007. http://news.independent.co.uk/ health/article2851984.ece (accessed 18 Jul 2008).
    • Independent
  • 53
    • 56749089519 scopus 로고    scopus 로고
    • Bannerman L. Parents 'bullying' GPs to get Prozac for children. The Times 17 Nov 2006. http://www.timesonline.co.uk/tol/news/uk/health/ article640047.ece (accessed 18 Jul 2008).
    • Bannerman L. Parents 'bullying' GPs to get Prozac for children. The Times 17 Nov 2006. http://www.timesonline.co.uk/tol/news/uk/health/ article640047.ece (accessed 18 Jul 2008).
  • 54
    • 85007690972 scopus 로고    scopus 로고
    • Treatment options may be limited by resources
    • Pelton CI. Treatment options may be limited by resources. BMJ 2005;330:418.
    • (2005) BMJ , vol.330 , pp. 418
    • Pelton, C.I.1
  • 55
    • 26444587079 scopus 로고    scopus 로고
    • DSM-IV or ICD-10-DCR diagnoses in child and adolescent psychiatry: Does it matter?
    • Sorenson MJ, Mors O, Thomson PH. DSM-IV or ICD-10-DCR diagnoses in child and adolescent psychiatry: does it matter? Eur Child Adolesc Psych 2006;14:335-40.
    • (2006) Eur Child Adolesc Psych , vol.14 , pp. 335-340
    • Sorenson, M.J.1    Mors, O.2    Thomson, P.H.3
  • 56
    • 34447622113 scopus 로고    scopus 로고
    • Depression in adolescents
    • Hazell P. Depression in adolescents. BMJ 2007;335:107.
    • (2007) BMJ , vol.335 , pp. 107
    • Hazell, P.1


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