Derivation of human embryonic stem cell lines from single cells of 4-cell stage embryos: Be aware of the risks

Human Reproduction

Volumn 23, Issue 12, 2008, Pages 2874-

  Feki, A ^a   Hovatta, O ^a,b   Jaconi, M ^c  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BLASTOCYST; BLASTOMERE; CHROMOSOME 18; CHROMOSOME 7; EMBRYONIC STEM CELL; LETTER; MORULA; OOCYTE; TOTIPOTENT STEM CELL;

EID: 56749096933     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/den369     Document Type: Letter

References (7)

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2. Draper JS, Smith K, Gokhale P, Moore HD, Maltby E, Johnson J, Meisner L, Zwaka TP, Thomson JA, Andrews PW. Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells. Nat Biotechnol 2004;22:53-54
3. Feki A, Bosman A, Dubuisson JB, Irion O, Dahoun S, Pelte MF, Hovatta O, Jaconi M. Derivation of a human embryonic stem cell line (ESC) from a single blastomere of an arrested stage four embryo. Swiss Medial Weekly 2008;138:540-550.
4. Hardarson T, Caisander G, Sjogren A, Hanson C, Hamberger L, Lundin K. A morphological and chromosomal study of blastocysts developing from morphologically suboptimal human pre-embryos compared with control blastocysts. Hum Reprod 2003;18:399-407.
5. Hovatta O, Mikkola M, Gertow K, Strömberg AM, Inzunza J, Hreinsson J, Andäng L, Ahrlund-Richter L. A culture system using human foreskin fibroblasts as feeder cells allows production of human embryonic stem cells. Hum Reprod 2003;18:1404-1409.
6. Streclchenko N, Verslinsky O, Kukharenko V, Verlisnky J. Morula-derived human embryonic stem cell lines. Reprod Biomed Online 2004;9:623-629.
7. Van de Velde H, Geens M, Mateiyel I, Spits C, Sermon K, De Rycke M, Van der Elst J, Devroey P, Tournaey H, Liebaers I. A human embryonic stem cell line derived from a single blastomere of a 4-cell stage embryo. ESHRE 2008, 6-9 July, Barcelona. Hum Reprod Abstract O-274.