Efficacy of methoxime and its homologues in reactivation of immobilized acetylcholinestrerase inhibited by sarin, cyclosarin and soman

Current Topics in Toxicology

Volumn 4, Issue , 2007, Pages 25-29

  Hoskovcová, Monika ^a   Halámek, Emil ^a   Kobliha, Zbyněk ^a   Tušarová, Ivana ^b  

^a UNIVERSITY OF DEFENCE   (Czech Republic)

^b Oritest Ltd   (Czech Republic)

Author keywords

Acetylcholinesterase; Biochemical reaction; Cyclosarin; Inhibition; Reactivation; Reactivators of AChe; Sarin; Soman

Indexed keywords

1,1' METHYLENEBIS(4 HYDROXYIMINOMETHYLPYRIDINIUM) DICHLORIDE; 5,5' DITHIOBIS(2 NITROBENZOIC ACID); ACETYLCHOLINESTERASE; ACETYLTHIOCHOLINE; CYCLOSARIN; METHOXIME; PYRIDINIUM DERIVATIVE; SARIN; SOMAN; UNCLASSIFIED DRUG;

ARTICLE; COLORIMETRY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME IMMOBILIZATION; ENZYME REACTIVATION; ENZYME STABILITY; ENZYMIC BIOSENSOR; REACTION TIME;

GOSSYPIUM HIRSUTUM;

EID: 56749093141     PISSN: 09728228     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Somani, S. M., Solana, R. P., and Dube, S. N. 1992, Chemical warfare Agents, Academic Press, UK.
2. Poziomek, E. J., Hackley B. E. jr., and Steinberg G. M. 1958, J. Org. Chem., 23, 714-718.
3. Petrová, I., and Bielavsý, J. 1999, Voj. Zdrav. L., 93, 20-37.
4. Reiner, E. 2001, Arh. Hig. R. Toksikol., 52, 323-331.
5. Tušarová, I., Halámek, E. 2001, Patent ČR 288 576.
6. Tušarová, I., Halámek, E., and Kobliha, Z. 1999, Enzyme Microb. Technol., 25,400-403.
7. Ellman, G. L. 1959, Arch. Biochem. Biophys., 82, 70-77.
8. Ellman, G. L., Courtney, K. D., Andres, V. jr., and Featherstone, R. M. 1961, Biochem. Pharmacol., 7, 88-95.